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1.
Pediatr Int ; 56(1): 31-4, 2014 Feb.
Article in English | MEDLINE | ID: mdl-24003938

ABSTRACT

BACKGROUND: The Children's Communication Checklist (CCC) was developed to provide an assessment of domains of language impairment in children, particularly the pragmatic domain. This study examined the effectiveness of the CCC-Thai version in discriminating children with autism spectrum disorders (ASD) from typically developing children. METHODS: The parents of two groups of 50 children aged 4-6 years, one with clinically ascertained ASD, and one with typical development, completed the CCC-Thai version. RESULTS: The mean pragmatic composite score was significantly lower in the ASD group (124.6) than in the typical development group (142). The optimal receiver operating characteristic curve cut-off score was found to be identical to the original English version (132). Corresponding sensitivity and specificity were 94% and 86%, respectively. The positive predictive value and the negative predictive value were 87% and 93%, respectively. The corresponding area under the curve was 0.95 (95% confidence interval: 0.91-0.99). CONCLUSION: The CCC-Thai version is a promising instrument to assess pragmatic language impairment in Thai children.


Subject(s)
Checklist/standards , Communication , Language Development Disorders/diagnosis , Risk Assessment/methods , Child , Child, Preschool , Female , Humans , Incidence , Language Development Disorders/epidemiology , Language Tests , Male , Prognosis , Psychometrics/methods , Reproducibility of Results , Retrospective Studies , Thailand/epidemiology
2.
Autism ; 16(4): 350-6, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22399447

ABSTRACT

This study aimed to examine the effectiveness of a translated version of the short version of the Developmental, Dimensional and Diagnostic Interview (3Di) in discriminating children with autism spectrum disorders (ASDs) from typically developing children. Two groups, comprising 63 children with clinically ascertained ASDs and 67 typically developing children, were interviewed with the short 3Di translated version. Mean 3Di scale scores in each domain of autistic symptoms (social reciprocity, communication, and repetitive/stereotyped behaviors) were significantly higher in the ASD group than in the typically developing group. The optimal receiver operating characteristics curve cut-off scores were found to be 10, 8, and 3 for social reciprocity domain, communication domain, and repetitive/stereotyped behaviors domain, respectively, which are identical to the original English standardization. Corresponding sensitivities and specificities were 76.2% and 80.9% for the social reciprocity domain; 85.7% and 73.5% for the communication domain; and 66.7% and 80.9% for the repetitive behaviors domain. The areas under the curve were 0.89 (95% CI = 0.84-0.94), 0.88 (95% CI = 0.82-0.94), and 0.79 (95% CI = 0.71-0.87), respectively. The short 3Di-Thai version is found to be a useful diagnostic instrument for differentiating between clinically diagnosed children with ASDs and typically developing children, although further replication is needed.


Subject(s)
Child Development Disorders, Pervasive/diagnosis , Interviews as Topic/methods , Case-Control Studies , Child , Child, Preschool , Cohort Studies , Female , Humans , Male , Predictive Value of Tests , ROC Curve , Sensitivity and Specificity , Social Behavior , Thailand
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