Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 10 de 10
Filter
1.
Violence Vict ; 37(2): 201-221, 2022 04 01.
Article in English | MEDLINE | ID: mdl-35354654

ABSTRACT

Nils Christie's (1986) ideal victim is said to receive "complete and legitimate status as a victim." Many victims of intimate partner sexual assault (IPSA), are not given this status, resulting in their cases being unfounded. The current study evaluates 16 years of reported IPSA cases (n = 1,558) in a large municipal police department in the midwestern United States. Through multivariate logistic regression this study evaluates which factors lead a reported IPSA case to be unfounded. Further, it examines how the IPSA victim fits into the concept of the ideal victim. The results indicate that several variables representing the ideal victim criteria are influence in unfounding IPSA cases; however, many are the opposite of what might be expected based on Christie's work. Results further indicate that race (victim race, detective race, racial composition of district) has a substantial impact on IPSA cases being unfounded.


Subject(s)
Crime Victims , Sex Offenses , Humans , Police , Sexual Behavior , Sexual Partners
2.
J Pediatr Pharmacol Ther ; 26(5): 508-511, 2021.
Article in English | MEDLINE | ID: mdl-34239405

ABSTRACT

Paget-Schroetter syndrome (PSS) is a rare syndrome that typically develops in young, healthy males subjected to repetitive overhead motions resulting in compression and thrombosis of the subclavian vein. This "effort thrombosis" typically occurs acutely in patients with specific anatomic variations within the thoracic outlet and is treated by a combination of surgical and pharmacologic interventions. There is a paucity of literature regarding this syndrome, particularly surrounding pharmacotherapy, and in the treatment of pediatric patients. This case report documents the pharmacologic treatment of a 17-year-old, male, baseball player with confirmed PSS. Apixaban was selected as the anticoagulant therapy of choice following the determination of its safety and anticipated efficacy for this pediatric patient. Upon admission, anticoagulation was initiated with intravenous heparin and transitioned to warfarin for 1 dose. On day 2, the patient was discharged with apixaban 10 mg twice daily for 7 days, followed by 5 mg twice daily. One week later, he underwent catheter-directed thrombectomy, followed by thoracic outlet decompression with resection of the first rib. Apixaban therapy was continued for 10 weeks after the procedure to diminish the risk of any further thrombotic events. This pediatric patient with PSS was successfully treated with apixaban in conjunction with surgical management. Treatment with apixaban resulted in continued resolution of thrombus after follow-up, with no complications reported thereafter. Further research is needed to definitively determine the safety and efficacy of apixaban for the use of pediatric anticoagulation, particularly in upper extremity deep vein thrombosis.

3.
J Vasc Surg ; 55(1): 1-8; discussion 8, 2012 Jan.
Article in English | MEDLINE | ID: mdl-21981799

ABSTRACT

BACKGROUND: Spinal cord ischemia (SCI) remains a significant concern in patients undergoing endovascular repair involving the thoracic aorta (thoracic endovascular aortic repair [TEVAR]). Perioperative lumbar spinal drainage has been widely practiced for open repair, but there is no consensus treatment protocol using lumbar drainage for SCI associated with TEVAR. This study analyzes the efficacy of an institutional protocol using selective lumbar drainage reserved for patients experiencing SCI following TEVAR. METHODS: A prospectively maintained registry was reviewed to identify all patients who underwent TEVAR from January 2000 through June 2010. Preoperative characteristics, intraoperative details, and outcomes, including neurologic deficit and mortality at 30 days and 1 year were determined based on reporting standards. Patients developing symptoms of SCI in the postoperative setting were compared with those without neurologic symptoms. SCI patients who received selective lumbar drainage were grouped based on resolution of neurologic function, with risk factors and outcomes of these subgroups analyzed with χ(2), t test, logistic regression, and analysis of variance (ANOVA). RESULTS: Two hundred seventy-eight TEVARs were performed on 251 patients. Twelve patients accounting for 12 TEVARs were excluded from analysis: 5 patients experienced SCI preoperatively, 4 patients were drained preoperatively, 2 expired intraoperatively, and 1 procedure was aborted. Of the remaining 266 procedures in 239 patients, 16 (6.0%) developed SCI within the 30-day postoperative period. Risk factors for SCI reaching statistical significance included length of aortic coverage (P = .036), existence of infrarenal aortic pathology (P = .026), and history of stroke (P = .043). Stent graft coverage of the left subclavian artery origin was required in 28.9% (n = 77) and was not associated with SCI (P = .52). Ten of 16 post-TEVAR SCI patients received selective postoperative lumbar drains and were categorized based on resolution of symptoms into complete resolution (n = 3; 30%), partial resolution (n = 4; 40%), and no resolution (n = 3; 30%). No patient characteristics or risk factors reached significance in comparison of lumbar drained patients and nondrained patients. All seven drained patients without complete resolution of SCI died within the first year after surgery, while all three of the complete responders survived (P = .017). In patients with SCI, increased all-cause mortality was observed at 1 year (56.3% vs 20.4%; P = .003). CONCLUSIONS: A protocol utilizing selective postoperative lumbar spinal drainage can be used safely for patients developing SCI after TEVAR with acceptably low permanent neurologic deficit, although overall survival of patients experiencing SCI after TEVAR is diminished relative to non-SCI patients.


Subject(s)
Aorta, Thoracic/surgery , Blood Vessel Prosthesis Implantation/adverse effects , Drainage/methods , Endovascular Procedures/adverse effects , Spinal Cord Ischemia/surgery , Aged , Alabama , Analysis of Variance , Blood Vessel Prosthesis Implantation/mortality , Chi-Square Distribution , Drainage/adverse effects , Drainage/mortality , Endovascular Procedures/mortality , Female , Humans , Logistic Models , Lumbosacral Region , Male , Middle Aged , Prospective Studies , Registries , Risk Assessment , Risk Factors , Spinal Cord Ischemia/etiology , Spinal Cord Ischemia/mortality , Time Factors , Treatment Outcome
4.
PLoS Negl Trop Dis ; 5(8): e1246, 2011 Aug.
Article in English | MEDLINE | ID: mdl-21829736

ABSTRACT

Human African Trypanosomiasis (HAT) is a major public health problem in the Democratic Republic of the Congo (DRC). Active and passive surveillance for HAT is conducted but may underestimate the true prevalence of the disease. We used ELISA to screen 7,769 leftover dried blood spots from a nationally representative population-based survey, the 2007 Demographic and Health Survey. 26 samples were positive by ELISA. Three of these were also positive by trypanolysis and/or PCR. From these data, we estimate that there were 18,592 people with HAT (95% confidence interval, 4,883-32,302) in the DRC in 2007, slightly more than twice as many as were reported.


Subject(s)
Trypanosomiasis, African/epidemiology , Adolescent , Adult , Antigens, Protozoan/blood , Democratic Republic of the Congo/epidemiology , Enzyme-Linked Immunosorbent Assay , Female , Health Surveys , Humans , Male , Middle Aged , Population Surveillance , Prevalence , Trypanosomiasis, African/blood
5.
World J Emerg Surg ; 6: 11, 2011 Apr 08.
Article in English | MEDLINE | ID: mdl-21477304

ABSTRACT

BACKGROUND: Extracranial traumatic cerebrovascular injury (TCVI) is present in 1-3% of all blunt force trauma patients. Although options for the management of patients with these lesions include anticoagulation, antiplatelet agents, and endovascular treatment, the optimal management strategy for patients with these lesions is not yet established. OBJECTIVE: Multidisciplinary survey of clinicians about current management of TCVI. METHODS: A six-item multiple-choice survey was sent by electronic mail to a total of 11,784 neurosurgeons, trauma surgeons, stroke neurologists, and interventional radiologists. The survey included questions about their choice of imaging, medical management, and the use of endovascular techniques. Survey responses were analyzed according to stated specialty. RESULTS: Seven hundred eighty-five (6.7%) responses were received. Overall, a total of 325 (42.8%) respondents favored anticoagulation (heparin and/or warfarin), 247 (32.5%) favored antiplatelet drugs, 130 (17.1%) preferred both anticoagulation and antiplatelet drugs, and 57 (7.5%) preferred stenting and/or embolization. Anticoagulation was the most commonly preferred treatment among vascular surgeons (56.9%), neurologists (50.2%) and neurosurgeons (40.7%), whereas antiplatelet agents were the most common preferred treatment among trauma surgeons (41.5%). Overall, 158 (20.7%) of respondents recommended treatment of asymptomatic dissections and traumatic aneurysms, 211 (27.7%) did not recommend it, and 39.4% recommended endovascular treatment only if there is worsening of the lesion on follow-up imaging. CONCLUSIONS: These data demonstrate the wide variability of physicians' management of traumatic cerebrovascular injury, both on an individual basis, and between specialties. These findings underscore the need for multicenter, randomized trials in this field.

6.
Ann Vasc Surg ; 25(1): 94-100, 2011 Jan.
Article in English | MEDLINE | ID: mdl-21172584

ABSTRACT

BACKGROUND: Endovascular repair for abdominal aortic aneurysm (EVAR) requires regular surveillance to ensure long-term durability. To understand the clinical consequence of discrepancies in endoleak detection between computed tomographic angiography (CTA) and duplex ultrasound (DUS) imaging, this study evaluated patients who underwent EVAR. The aim of the present study was to determine whether these discrepancies affected the long-term outcome after EVAR, and whether DUS predicted the need for re-intervention on the basis of other markers despite missing endoleaks. METHODS: A review of the prospectively maintained database was completed to capture all EVAR procedures performed between October 1999 and June 2009. Patients were routinely evaluated with computed tomography (CT) and DUS imaging within 30 days after the procedure and intermittently at 6-12 month intervals after treatment. DUS imaging was evaluated with attention toward maximum aneurysm diameter, presence of an endoleak, and compared with findings on simultaneous contrast CT imaging. RESULTS: The database and patient records identified 1,062 EVARs in 992 patients who underwent 3,120 imaging encounters through the surveillance protocol. Of these 3,120 encounters, 610 had both CT scan and ultrasound at the same visit. Contrast material was not used in 49 CT scans, leaving 561 encounters for comparing contrast CT imaging with DUS results. CT and DUS detection of endoleaks correlated in 442 encounters (78.8%). Discrepancies occurred in 119 encounters (21.2%) as follows: CT scan only endoleak in 17.8% (N = 100; type I = 6, type II = 91, and type III = 3) and DUS only endoleak in 3.4% (N = 19; type II = 19) encounters. Of these 119 encounters, 99 (17.6%) did not require secondary interventions. Eventually, 15 patients required intervention after 20 discrepancy encounters (3.6%): 11 patients continued with the surveillance protocol through CT or DUS imaging, whereas four were observed by CT imaging only. Considering these 11 patients, DUS eventually detected an endoleak on subsequent visits in five patients, DUS identified an increase in aneurysm diameter in four patients, and DUS never identified the type II endoleaks in two patients. When the endoleak raised concern or the aneurysm enlarged, we undertook 19 secondary interventions in these 15 patients: vessel embolization (N = 8), iliac extenders (N = 5), graft relining (N = 3), graft explants (N = 2), and proximal cuff (N = 1). Although three ruptures occurred in our entire treatment experience, no ruptures occurred in patients who maintained the prescribed surveillance protocol. CONCLUSION: Surveillance after EVAR is necessary because secondary interventions are sometimes required. Although DUS has lower sensitivity in detecting endoleaks, comparison with CT findings can identify the appropriate patients for DUS surveillance only. Even considering the discrepancies between CT imaging and DUS, repeated DUS surveillance might identify an unstable aneurysm that requires further intervention. Although DUS has not been established as an exclusive surveillance tool, it can be used to effectively monitor patients after EVAR with reduced need for CT imaging.


Subject(s)
Aortic Aneurysm, Abdominal/surgery , Aortography/methods , Blood Vessel Prosthesis Implantation/instrumentation , Blood Vessel Prosthesis , Endoleak/diagnostic imaging , Endovascular Procedures/instrumentation , Prosthesis Failure , Tomography, X-Ray Computed , Ultrasonography, Doppler, Color , Ultrasonography, Interventional , Aged , Aged, 80 and over , Alabama , Blood Vessel Prosthesis Implantation/adverse effects , Chi-Square Distribution , Endoleak/etiology , Endoleak/surgery , Endovascular Procedures/adverse effects , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Registries , Reoperation , Retrospective Studies , Sensitivity and Specificity , Treatment Outcome
7.
J Vasc Surg ; 51(5): 1215-21, 2010 May.
Article in English | MEDLINE | ID: mdl-20223628

ABSTRACT

BACKGROUND: Although contrast venography is the standard imaging method for inferior vena cava (IVC) filter insertion, intravascular ultrasound (IVUS) imaging is a safe and effective option that allows for bedside filter placement and is especially advantageous for immobilized critically ill patients by limiting resource use, risk of transportation, and cost. This study reviewed the effectiveness of a prospectively implemented algorithm for IVUS-guided IVC filter placement in this high-risk population. METHODS: Current evidence-based guidelines were used to create a clinical decision algorithm for IVUS-guided IVC filter placement in critically ill patients. After a defined lead-in phase to allow dissemination of techniques, the algorithm was prospectively implemented on January 1, 2008. Data were collected for 1 year using accepted reporting standards and a quality assurance review performed based on intent-to-treat at 6, 12, and 18 months. RESULTS: As defined in the prospectively implemented algorithm, 109 patients met criteria for IVUS-directed bedside IVC filter placement. Technical feasibility was 98.1%. Only 2 patients had inadequate IVUS visualization for bedside filter placement and required subsequent placement in the endovascular suite. Technical success, defined as proper deployment in an infrarenal position, was achieved in 104 of the remaining 107 patients (97.2%). The filter was permanent in 21 (19.6%) and retrievable in 86 (80.3%). The single-puncture technique was used in 101 (94.4%), with additional dual access required in 6 (5.6%). Periprocedural complications were rare but included malpositioning requiring retrieval and repositioning in three patients, filter tilt >/=15 degrees in two, and arteriovenous fistula in one. The 30-day mortality rate for the bedside group was 5.5%, with no filter-related deaths. CONCLUSIONS: Successful placement of IVC filters using IVUS-guided imaging at the bedside in critically ill patients can be established through an evidence-based prospectively implemented algorithm, thereby limiting the need for transport in this high-risk population.


Subject(s)
Algorithms , Point-of-Care Systems , Ultrasonography, Interventional/methods , Vena Cava Filters , Venous Thromboembolism/mortality , Venous Thromboembolism/prevention & control , Adolescent , Adult , Aged , Critical Care/methods , Critical Care/standards , Critical Illness/therapy , Evidence-Based Medicine , Female , Humans , Male , Middle Aged , Phlebography/methods , Prospective Studies , Pulmonary Embolism/mortality , Pulmonary Embolism/prevention & control , Risk Assessment , Treatment Outcome , Young Adult
8.
Vasc Endovascular Surg ; 42(2): 113-9; discussion 120-1, 2008.
Article in English | MEDLINE | ID: mdl-18270271

ABSTRACT

The outcomes of endovascular repair for small abdominal aortic aneurysm (4.0-4.9 cm) is reported. All patients undergoing endovascular abdominal aortic aneurysm repair between 2000 and 2006 with maximal diameter 4.0 to 4.9 cm form the small aneurysm study cohort. Data were analyzed retrospectively and life-table methods were used. Of 743 endovascular repairs, 132 (17.8%) were performed for small abdominal aortic aneurysm. Perioperative complication rate was 9.1%. Freedom from aneurysm expansion was 96% at 1 year, 86% at 3 years, and 77% at 5 years. Overall survival was 98%, 93%, and 84% at 1, 3, and 5 years, respectively. Perioperative 30-day mortality was 0.8% with an aneurysm-related mortality of 1.5% at 5 years. There were no deaths from delayed aneurysm rupture. Endovascular repair of small abdominal aortic aneurysm is associated with low perioperative morbidity and mortality compared with published results for open repair, and treatment threshold can be reduced to 4 cm in selected patients.


Subject(s)
Aortic Aneurysm, Abdominal/surgery , Blood Vessel Prosthesis Implantation , Patient Selection , Aged , Aged, 80 and over , Aortic Aneurysm, Abdominal/mortality , Aortic Aneurysm, Abdominal/pathology , Blood Vessel Prosthesis , Blood Vessel Prosthesis Implantation/adverse effects , Blood Vessel Prosthesis Implantation/instrumentation , Female , Humans , Life Tables , Male , Middle Aged , Prosthesis Design , Retrospective Studies , Risk Assessment , Secondary Prevention , Stents , Survival Analysis , Time Factors , Treatment Outcome
9.
Ann Vasc Surg ; 19(6): 782-6, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16228806

ABSTRACT

Aortic stent graft repair has recently been applied as an alternative therapy for infrarenal ruptured abdominal aortic aneurysms (rAAAs). We retrospectively assessed outcome in a continuous series at a single institution (an academic tertiary referral center) of patients with infrarenal rAAAs treated by either open or endovascular repair. Between October 1999 and July 2004, 24 patients were treated at the University of Alabama Hospital for infrarenal rAAA. They were treated by either open procedure (n = 15) or endovascular stent graft repair (n = 9). Outcome parameters included mortality, morbidity, procedure time, blood loss, and length of stay. Endovascular aneurysm repair (EVAR) was performed whenever the anatomy was deemed suitable and experienced personnel were available. Age (mean 70.8 years for EVAR vs. 72.2 years for open), gender (men 71% vs. women 75%), AAA size (mean 6.7 vs. 6.4 cm), early mortality (22% vs. 26%), and major morbidity (56% vs. 53%) were similar in both groups. Blood loss difference between the two groups was statistically significant (p = 0.0001). Our series supports the feasibility and short-term viability of EVAR for infrarenal rAAA when anatomy is suitable and patient and facility conditions are favorable.


Subject(s)
Aortic Aneurysm, Abdominal/surgery , Aortic Rupture/surgery , Aged , Blood Loss, Surgical , Female , Humans , Length of Stay , Male , Retrospective Studies , Stents , Treatment Outcome , Vascular Surgical Procedures
10.
Ann Vasc Surg ; 19(2): 192-8, 2005 Mar.
Article in English | MEDLINE | ID: mdl-15770370

ABSTRACT

When polytetrafluoroethylene (PTFE) must be used for below-knee bypass to achieve limb salvage, effective anticoagulation with warfarin may improve graft survival. We analyzed our practice of routinely using oral anticoagulation to improve graft patency rates for PTFE grafts to below-knee popliteal and crural vessels in limb salvage procedures. We reviewed our established vascular database from February 1999 through April 2003 to identify those patients who required below-knee and tibial artery bypass with PTFE for critical limb ischemia. All patients were initiated on warfarin anticoagulation postoperatively, with an international normalized ratio (INR) of 2.0-3.0 considered therapeutic. All patients were discharged in the therapeutic range. Life-table analysis and Kaplan-Meier estimates were used to compare primary patency rates with regard to INR and position of distal anastomosis. Cox proportional hazards analysis was performed to compare the patency rates for grafts with therapeutic versus subtherapeutic anticoagulation while correcting for variability in distal runoff. Between February 1999 and April 2003, 74 patients (mean age, 69.2 years; 58% men) had 77 below-knee PTFE bypasses. Indications for operation included rest pain (43), ischemic ulcer (27), and gangrene (7). Patients presenting with occluded grafts more often had a subtherapeutic INR. Patients with a subtherapeutic INR (< or = 1.9) had a median primary graft patency of 6.8 months and those with a therapeutic INR (> or = 2.0) had a median primary graft patency of 29.9 months (p = 0.0007). Analysis by Cox proportional hazards model demonstrated a significantly better graft patency rate in patients with a therapeutic INR regardless of outflow vessel. The patency rates of PTFE grafts to infrageniculate vessels may be improved by effective anticoagulation with warfarin. This improved patency rate may also result in improved limb salvage and further support the use of PTFE grafts for critical limb ischemia when autogenous vein is not available. Predictably, the best results are seen with an INR therapeutic range of 2.0 to 3.0.


Subject(s)
Anticoagulants/therapeutic use , Blood Vessel Prosthesis , Leg/blood supply , Polytetrafluoroethylene , Vascular Patency , Warfarin/therapeutic use , Aged , Blood Vessel Prosthesis Implantation , Female , Graft Survival , Humans , Male , Popliteal Artery/surgery , Postoperative Care , Proportional Hazards Models
SELECTION OF CITATIONS
SEARCH DETAIL
...