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Georgian Med News ; (237): 64-70, 2014 Dec.
Article in Russian | MEDLINE | ID: mdl-25617104

ABSTRACT

The possibility of using a hydrogel based on divinyl ether co- and terpolymer of diethylene glycol as the backbone polymer for incorporating water-soluble medicinal substances was examined. The character of the influence of emulsifiers, plasticizers, high-boiling liquids and bioactive substances is defined within the changes of physical-chemical properties of obtained hydrogels. The obtained polyelectrolyte hydrogels by their homogeneity, dehydration and rheological characteristics may be of concern in function of matrices to create external prolonged-action dosage forms.


Subject(s)
Chemistry, Pharmaceutical , Hydrogel, Polyethylene Glycol Dimethacrylate/chemistry , Ointments/chemistry , Ethylene Glycols/chemistry , Ethylene Glycols/therapeutic use , Humans , Hydrogel, Polyethylene Glycol Dimethacrylate/therapeutic use , Ointments/therapeutic use , Vinyl Compounds/chemistry , Vinyl Compounds/therapeutic use , Water/chemistry
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