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1.
Environ Health Prev Med ; 26(1): 52, 2021 Apr 30.
Article in English | MEDLINE | ID: mdl-33941074

ABSTRACT

INTRODUCTION: The survival of HIV/AIDS patients on antiretroviral therapy (ART) is determined by a number of factors, including economic, demographic, behavioral, and institutional factors. Understanding the survival time and its trend is crucial to developing policies that will result in changes. The aim of this study was to compare the survival estimates of different subgroups and look into the predictors of HIV/AIDS patient survival. METHODS: A retrospective cohort study of HIV/AIDS patients receiving ART at the University of Gondar teaching hospital was carried out. To compare the survival of various groups, a Kaplan-Meier survival analysis was performed. The Cox proportional hazards model was used to identify factors influencing HIV/AIDS patient survival rates. RESULTS: In the current study, 5.91% of the 354 HIV/AIDS patients under ART follow-up were uncensored or died. Age (HR = 1.051) and lack of formal education (HR = 5.032) were associated with lower survival rate, whereas family size of one to two (HR = 0.167), three to four (HR = 0.120), no alcoholic consumption (HR = 0.294), no smoking and chat use (HR = 0.101), baseline weight (HR = 0.920), current weight (HR = 0.928), baseline CD4 cell count (HR = 0.990), baseline hemoglobin (HR = 0.800), and no TB diseases were associated with longer survival rate. CONCLUSIONS: Fewer deaths were reported in a study area due to high patient adherence, compared to previous similar studies. Age, educational status, family size, alcohol consumption, tobacco and chat usage, baseline and current weight, baseline CD4 cell count, baseline hemoglobin, and tuberculosis (TB) diseases were all significant predictors of survival of HIV/AIDS patients.


Subject(s)
Anti-HIV Agents/therapeutic use , HIV Infections/mortality , Adolescent , Adult , Aged , Aged, 80 and over , Cohort Studies , Ethiopia/epidemiology , Female , HIV Infections/drug therapy , Hospitals , Humans , Male , Middle Aged , Proportional Hazards Models , Retrospective Studies , Survival Rate , Young Adult
2.
Environ Health Insights ; 14: 1178630220978234, 2020.
Article in English | MEDLINE | ID: mdl-33335399

ABSTRACT

This community-based cross-sectional study was conducted to investigate the indoor concentration of carbon monoxide (CO) and associated factors in residential buildings of Gondar town, northwest Ethiopia. Data were collected from 384 occupied buildings and occupants using CO meter, interviewers administered questionnaire, and observation checklists. Multivariable binary logistic regression analysis was used for controlling the possible effect of confounders and to identify factors associated with indoor concentration of CO on the basis of adjusted odds ratio (AOR) with 95% confidence interval (CI) and P < .05. The current study revealed that 224(58.3%) occupied buildings had the concentration of CO above the permissible value for 15 minute exposure for living rooms (100 mg/m3). Indoor concentration of CO was significantly associated with access to health information [AOR = 0.081, 95%CI = (0.008, 0.803)], number of rooms [AOR = 0.016, 95% CI = (0.001, 0.279)], area of occupied room [AOR = 0.019, 95% CI = (0.001, 0.237)], buildings located away from main roads/garages [AOR = 0.045, 95% CI = (0.005, 0.415)], clean energy sources [AOR = 0.010, 95% CI = (0.001, 0.123)], presence of separate kitchen [AOR = 0.030, 95% CI = (0.004, 0.221)], no incensing in the room [AOR = 0.055, 95% CI = (0.006,0.499)] and measurements in the afternoon [AOR = 0.114, 95% CI = (0.013, 0.965)]. Residents, therefore, need to use clean energy sources, construct a kitchen with a properly constructed chimneys away from the main building, and avoid incensing inside the indoor environment.

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