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1.
Biofizika ; 53(1): 123-8, 2008.
Article in Russian | MEDLINE | ID: mdl-18488511

ABSTRACT

The integral area of gas discharge luminescence of the hand finger skin and the activity of succinate dehydrogenase in lymphocytes in blood smears from patients with food allergia and attendant hypertension has been measured. Succinate dehydrogenase in these patients was hyperactivated or inhibited as compared with healthy persons. At more substantial deviations of activity, a more clearly pronounced hypertension was observed. The area of luminescence of the skin in some patients was near the upper boundary of norm or was beyond its limits. A high degree of correlation (r = 0.85) between the two parameters has been revealed. At moderate and high succinate dehydrogenase activity, the parameters of gas-discharge visualization decreased; the inhibition of succinate dehydrogenase activity enhances, the gas-discharge visualization increases. This probably indicates the contribution to the irradiation from hand fingers of the superoxide formed in the respiratory chain of mitochondria in the region of coenzyme Q upon its incomplete reduction caused by the inhibition of succinate dehydrogenase.


Subject(s)
Lymphocytes/enzymology , Skin/physiopathology , Succinate Dehydrogenase/metabolism , Adult , Aged , Enzyme Activation , Female , Food Hypersensitivity/enzymology , Food Hypersensitivity/physiopathology , Humans , Hypertension/enzymology , Hypertension/physiopathology , Luminescent Measurements , Male , Middle Aged
2.
Probl Tuberk ; (6): 20-1, 1997.
Article in Russian | MEDLINE | ID: mdl-9503924

ABSTRACT

The tuberculosis mortality rate is the most informative epidemiological indicator. Tuberculosis mortality in the Sverdlovsk Region in 1989-1996 directly, closely, and significantly correlated with tuberculosis morbidity and general mortality. The structure of manpower losses caused by premature tuberculosis mortality due to antituberculosis work defects included one third of losses associated with the defects of antituberculosis work, about one fourth of those with the general therapeutical network, one tenth of those with sanitary epidemiological surveillance centers and another approximately one third with failure of detection and treatment of patients with tuberculosis.


Subject(s)
Tuberculosis/mortality , Humans , Retrospective Studies , Russia/epidemiology , Survival Rate/trends
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