ABSTRACT
The present study examined the use of antibiotics with respect to the rate of Chlamydia trachomatis positivity. Our subjects were 282 sexually active Turkish females between the ages of 15 and 42. Endocervical samples were investigated in 60 women with pelvic inflammatory diseases (PIDs), 90 infertile patients (IPs), 92 registered commercial sex workers (CSWs), and 40 intrauterine device (IUD) users. All samples were analyzed using direct immunofluorescence test techniques for the presence of C. trachomatis antigen, which was found in 12.7% of our subjects, with positive results as high as 26% in patients between 21 and 30 years of age. C. trachomatis positivity was found to be 16.6% in PID patients, and 23.3% in IPs, and 5.4% in CSWs; however, it was not found among IUD users. The rate of positivity was highest in IPs; and lowest in registered CSWs (P < 0.05), who are periodically examined for the presence of sexually transmitted diseases, as required by Turkish authorities. Interestingly, the usage of therapeutic or prophylactic antibiotics such as tetracycline and ceftriaxon was found to be quite high among IUD users (90% use of tetracycline) and CSWs (100% use of both antibiotcs). Our results show that C. trachomatis positivity in the southeast region of Turkey is not significantly higher than that found in previous studies on sex workers of other countries. Additionally, our results indicate the use of prophylactic antibiotics decreases the rate of chlamydial infections.
