Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 2 de 2
Filter
Add more filters










Database
Language
Publication year range
1.
Pacing Clin Electrophysiol ; 36(7): 811-22, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23448231

ABSTRACT

BACKGROUND: We developed and evaluated a novel system for guiding radiofrequency catheter ablation therapy of ventricular tachycardia. This guidance system employs an inverse solution guidance algorithm (ISGA) using a single equivalent moving dipole (SEMD) localization method. The method and system were evaluated in both a saline tank phantom model and in vivo animal (swine) experiments. METHODS: A catheter with two platinum electrodes spaced 3 mm apart was used as the dipole source in the phantom study. A 40-Hz sinusoidal signal was applied to the electrode pair. In the animal study, four to eight electrodes were sutured onto the right ventricle. These electrodes were connected to a stimulus generator delivering 1-ms duration pacing pulses. Signals were recorded from 64 electrodes, located either on the inner surface of the saline tank or on the body surface of the pig, and then processed by the ISGA to localize the physical or bioelectrical SEMD. RESULTS: In the phantom studies, the guidance algorithm was used to advance a catheter tip to the location of the source dipole. The distance from the final position of the catheter tip to the position of the target dipole was 2.22 ± 0.78 mm in real space and 1.38 ± 0.78 mm in image space (computational space). The ISGA successfully tracked the locations of electrodes sutured on the ventricular myocardium and the movement of an endocardial catheter placed in the animal's right ventricle. CONCLUSION: In conclusion, we successfully demonstrated the feasibility of using an SEMD inverse algorithm to guide a cardiac ablation catheter.


Subject(s)
Algorithms , Body Surface Potential Mapping/methods , Catheter Ablation/methods , Heart Conduction System/physiology , Heart Conduction System/surgery , Models, Cardiovascular , Surgery, Computer-Assisted/methods , Animals , Body Surface Potential Mapping/instrumentation , Computer Simulation , Phantoms, Imaging , Reproducibility of Results , Sensitivity and Specificity , Surgery, Computer-Assisted/instrumentation , Swine
SELECTION OF CITATIONS
SEARCH DETAIL
...