ABSTRACT
Statistics for the last 6 years show a trend to growing number of new cases with tuberculosis of the lungs with drug-resistant pathogen. In recurrent tuberculosis multiple drug resistance (MDR) was three times higher than in new cases. Treatment efficacy depended on MDR and patients' compliance. The results of the basic treatment course were unstable: many patients had exacerbation within 3-4 years after therapy, many patients died, especially those with M. tuberculosis resistant to many drugs.
Subject(s)
Antibiotics, Antitubercular/therapeutic use , Antitubercular Agents/therapeutic use , Isoniazid/therapeutic use , Rifampin/therapeutic use , Tuberculosis, Multidrug-Resistant/epidemiology , Tuberculosis, Pulmonary/drug therapy , Humans , Incidence , Moscow/epidemiology , Mycobacterium tuberculosis/drug effects , Mycobacterium tuberculosis/isolation & purification , Mycobacterium tuberculosis/pathogenicity , Retrospective Studies , Sputum/microbiology , Tuberculosis, Multidrug-Resistant/diagnosis , Tuberculosis, Pulmonary/diagnosis , Tuberculosis, Pulmonary/epidemiologyABSTRACT
There are 77.1% of new cases in antituberculous dispensary registry group IA. The proportion of patients diagnosed at hospitals of different disciplines has been higher that of patients identified at preventive fluorography. In 18.3% of cases, group IA has been replenished by patients with exacerbation and recrudescence; 4.6% has come from imprisonments, 17.8% of antituberculous dispensary registry group IA patients are socially disadaptive. The most severe destructive forms of tuberculosis with bacterial isolates detected at bacterioscopy are common mainly in patients whose disease has been diagnosed due to pulmonary complains in polyclinics and hospitals. Various concomitant diseases are present in 82.3%, 10.3% of patients are followed up in group IA for more than 3 years.
Subject(s)
Ambulatory Care Facilities , Outpatients/classification , Registries , Tuberculosis, Pulmonary/epidemiology , Adolescent , Adult , Female , Humans , Incidence , Male , Middle Aged , Mycobacterium tuberculosis/isolation & purification , Patient Selection , Retrospective Studies , Russia/epidemiology , Social Class , Tuberculosis, Pulmonary/diagnosis , Tuberculosis, Pulmonary/prevention & controlABSTRACT
The patients whom tuberculosis was detected at general somatic hospitals form 28% in the make-up of dispensary registry group IA. In these hospitals BC are found in those with suspected tuberculosis and even in its destructive forms (4-5.7%). Activization of explanatory work with physicians and nurses at a hospital has caused an increase in positive sputum tests for BC and favoured a 7-fold increase in their detection by bacterioscopy after Ziehl-Neelsen.
Subject(s)
Ambulatory Care Facilities , Hospitals, General/methods , Tuberculosis, Pulmonary/diagnosis , Adult , Aged , Aged, 80 and over , Ambulatory Care Facilities/organization & administration , Female , Humans , Male , Middle Aged , Registries , Retrospective Studies , Russia , Tuberculosis, Pulmonary/prevention & controlABSTRACT
Disability was analyzed in 270 patients with pulmonary tuberculosis detected in 1995-1997. Today the level of disability and its associated expenses on payment of allowances due to the working incapacity of patients with pulmonary tuberculosis are more and more determined by different poor social factors, such as the specific features of the labour market, unemployment, lower living conditions of most patients with this disease.
