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1.
Klin Lab Diagn ; (7): 3-5, 2002 Jul.
Article in Russian | MEDLINE | ID: mdl-12187589

ABSTRACT

The aim of this study was to evaluate myocardial cell damage after radiofrequency ablation (RFA), one of the most effective methods for the treatment of arrhythmias. Thirty patients aged 30.4 +/- 8.6 years were examined. Biochemical parameters were evaluated repeatedly 6-18 h after RFA. Positive troponin T (Tn-T) test and increased CK-Mb activity (p < 0.22) were observed in 8 patients (group 1), while in group II Tn-T test was negative. Biochemical findings in group I correlated with the results of ECG body surface mapping (STT) (negative area), duration and number of RFA lesions. Myocardial damage was detected using 3 cardiac markers: myo/CK-Mb and Tn-T. These testing should be carried out in due time repeatedly, in order to catch the STT maps and biochemical parameters were in high correlation after RFA. Presumably, T-wave abnormalities in Tn-T-negative group after RFA were due to the cardiac memory phenomenon. Myo/CK-Mb after RFA in Tn-T-positive group coincided with that in acute myocardial infarction. Hence, myocardial damage after RFA can be confirmed by the Tn-T test, which is helpful in the differential diagnosis of minor myocardial damage and cardiac memory phenomenon.


Subject(s)
Catheter Ablation/adverse effects , Creatine Kinase/blood , Isoenzymes/blood , Myocardium/metabolism , Myoglobin/analysis , Tachycardia, Paroxysmal/surgery , Troponin T/blood , Wolff-Parkinson-White Syndrome/surgery , Adult , Creatine Kinase, MB Form , Electrocardiography , Heart/physiopathology , Humans , Tachycardia, Paroxysmal/diagnosis , Tachycardia, Paroxysmal/physiopathology , Wolff-Parkinson-White Syndrome/diagnosis , Wolff-Parkinson-White Syndrome/physiopathology
2.
Fiziol Zh Im I M Sechenova ; 79(9): 18-25, 1993 Sep.
Article in Russian | MEDLINE | ID: mdl-8268988

ABSTRACT

Subsynaptic fractions from light and heavy synaptosomes of the cat temporal associative cortex were tested for choline-acetyltransferase activity in respect to ability of preverbal notion formation. Most of the fractions revealed no connection with the intellectual capacity. Involvement of the cholinergic synapses of the temporal associative cortex in functions of generalisation and abstraction, is discussed.


Subject(s)
Cognition/physiology , Receptors, Cholinergic/physiology , Synapses/physiology , Temporal Lobe/physiology , Acetylcholine/metabolism , Animals , Brain Chemistry , Cats , Choline O-Acetyltransferase/metabolism , Female , Male , Neuropsychological Tests , Synaptosomes/chemistry , Synaptosomes/enzymology , Temporal Lobe/chemistry
3.
Article in Russian | MEDLINE | ID: mdl-8249462

ABSTRACT

In neuropsychophysiological and biochemical experiments was studied the role of the temporal cortex of the cat (AI, AII) in mnemonic, perceptive, gnostic functions, praxis, and the higher cognitive processes. The participation of the temporal fields in the mechanisms forming the gnostic imagery activity was shown.


Subject(s)
Cognition/physiology , Sensation/physiology , Temporal Lobe/physiology , Acetylcholine/metabolism , Animals , Cats , Feeding Behavior/physiology , Female , Male , Membrane Proteins/metabolism , Photic Stimulation , Psychophysiology , Synapses/metabolism , Temporal Lobe/surgery
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