ABSTRACT
A cross-sectional study of a representative sample of boys aged 7-17 years (n=569) was carried out in Arkhangelsk. The rate of asymptomatic hyperuricemia was 27.59 %. Serum level of uric acid correlated with levels of triglycerides, total cholesterol, low density lipoprotein cholesterol, fasting glycemia, systolic and diastolic blood pressure (r = 0.49; 0.27; 0.27; 0.26; 0.34 u 0.35, respectively; p<0,05). Prevalence of borderline and pronounced hyperlipidemia, elevated blood pressure, and impaired fasting glycemia among children with elevated uric acid level was higher than among children with normal level of uric acid. Chronic asymptomatic hyperuricemia in childhood can be regarded as marker of atherogenic risk because of its association with atherogenic phenotype of lipids and lipoproteins levels, increased fasting glycemia and elevated blood pressure.
Subject(s)
Atherosclerosis/etiology , Hyperuricemia/epidemiology , Adolescent , Age Factors , Atherosclerosis/epidemiology , Biomarkers , Blood Glucose/analysis , Blood Pressure , Chi-Square Distribution , Child , Chronic Disease , Humans , Hyperlipidemias/complications , Hyperlipidemias/diagnosis , Hyperuricemia/complications , Male , Risk Factors , Russia/epidemiology , Sex Factors , Uric Acid/bloodABSTRACT
Authors examined 539 schoolgirls in the age 7-16 years old. Dosorders of lipid metabolism occurred in 48.4% of cases; hyperuricemia more than 0.32 mmol/l--in 25% of cases; excessive body weight and obesity--in 15% of cases. So more than half of female population some metabolic disorders. High frequency of metabolic disorders prove the necessity of dietetic correction in dependence on type of prevailed metabolic changes. Diet counted all the amount of metabolic disorders must be most effective.
Subject(s)
Metabolic Diseases/diet therapy , Metabolic Diseases/diagnosis , Adolescent , Blood Pressure , Body Weight , Child , Diet Therapy/methods , Female , Humans , Hyperlipidemias/diagnosis , Hyperlipidemias/diet therapy , Hyperuricemia/diagnosis , Hyperuricemia/diet therapy , Obesity/diagnosis , Obesity/diet therapy , Purines/metabolism , Reference ValuesABSTRACT
Virological and cytochemical parameters of blood leukocytes during acute stenosing laryngotracheitis in 53 children were measured, viz. succinate dehydrogenase, mitochondrial alpha-glycerophosphate dehydrogenase, acid and alkaline phosphatase, myeloperoxidase. The patients were subjected to a combined treatment which included metabolites and their cofactors. The treatment gave good results, shortening the duration and reducing the number of relapses of the disease.
