Subject(s)
Carcinoembryonic Antigen/analysis , Colonic Neoplasms/diagnosis , Rectal Neoplasms/diagnosis , Adolescent , Adult , Aged , Humans , Middle AgedABSTRACT
During the period 1959 to 1968, a total of 158 patients with carcinoma of the rectum were treated at the surgical department of the Oncological Institute in Bratislava. All these patients were retro spectively classified according to the TNM system into four clinical stages as follows: Stage I -- 26 (16.46%). Stage II -- 12 (7.59%), Stage III -- 61 (36.61%) and Stage IV -- 59 (53.39%) of the patient. Surgical treatment was supplemented with irradiation in 85 (53.73%) of the patients with chemotherapy in 15 (9.49%). All the findings were verified histologically. Favorable results as regards the 5-year survival rate in accordance with literature data were achieved in the early stages of the affection, while in advanced stages this survival rate was rather low, the majority of the patients died in the first and second year following initiation of treatment. The authors express the view that in future, oncologists will have to devote more attention to an early diagnosis and treatment of precanceroses, and this not solely in patients with a carcinoma of the rectum, but also in its other localizations.
Subject(s)
Rectal Neoplasms/therapy , Adult , Aged , Female , Follow-Up Studies , Humans , Male , Middle Aged , Neoplasm Metastasis , Rectal Neoplasms/mortality , Rectal Neoplasms/surgeryABSTRACT
The authors have analysed 43 patients with thyroid carcinoma who had been treated at the surgery department of the Oncological Institute between 1960 and 1970. The patients are distributed in four groups according to the histologic tumor structure. Considering the specific properties of each particular group, the occurrence of metastases, treatment, survival and prognosis are being discussed. An outline is given on the characteristics of the various forms of thyroid carcinoma from the histological but mainly clinical aspects. The development of regional and distant metastases, surgical treatment, postoperative irradiation or application of radioiodine and hormonal tumor dependence are presented in the paper. The best results were obtained in the papillary and the follicular form, the prognosis in the latter being dependent on the degree of vascular invasion. The solid carcinoma of thyroid shows considerable differences in survival of patients depending on regional metastases and histologic grade. The anaplastic carcinoma has the worst prognosis where survival is expressed in months, exceptions are rare.
