ABSTRACT
A retrospective study was undertaken to determine the relative incidence of all eyelid lesions (720 cases) submitted to the Wills ophthalmic pathology laboratory between July 1, 1980, and June 30, 1982. Data on age, sex, location, and diagnostic accuracy were also tabulated. One hundred twenty-five (17.4%) malignant lesions were found. The most common lesion of the eyelid was basal cell carcinoma, which represented 14.3% of the total and 82.4% of the malignant lesions. Differences between malignant and benign lesions were searched for. The data suggests that lesions occurring in the upper lid are much less likely to be malignant than those occurring elsewhere. Among the 125 malignant lesions, clinicians were 92.8% accurate in predicting malignancy.
Subject(s)
Eyelid Neoplasms/pathology , Eyelid Diseases/epidemiology , Eyelid Diseases/pathology , Eyelid Neoplasms/epidemiology , Female , Humans , Male , Pennsylvania , Prognosis , Retrospective StudiesABSTRACT
The late onset of glaucoma occurs in approximately 7% of eyes with traumatic angle cleavage. We studied 13 patients who developed glaucoma in the angle-cleavage eye at an average of 34 years following trauma. Ten of the 13 patients had 270 degrees or more of angle cleavage. At the time of the initial diagnosis of angle cleavage glaucoma, there were no optic disc or visual field abnormalities in the fellow eyes. After a mean follow-up of 7.7 years, all 13 patients were reevaluated. In addition to standard examination techniques, all underwent disc photos, goniophotos, and Octopus perimetry. Seven of 13 patients (55%) had either frank glaucomatous or suspicious Octopus visual field abnormalities in the fellow eyes. Patients with angle-cleavage glaucoma appear to have at least a 50% chance of developing open-angle glaucoma in the non-traumatized fellow eyes.
Subject(s)
Ciliary Body/injuries , Glaucoma, Open-Angle/diagnosis , Wounds, Nonpenetrating/complications , Adolescent , Adult , Aged , Child , Ciliary Body/pathology , Female , Follow-Up Studies , Glaucoma, Open-Angle/pathology , Humans , Intraocular Pressure , Male , Middle Aged , Visual Fields , Wounds, Nonpenetrating/pathologyABSTRACT
We report a boy with severe congenital osteopetrosis who underwent splenectomy at age 4, with simultaneous transplantation of portions of the spleen into the anterior rectus compartments. Despite demonstrated survival and partial functioning of the splenic implants, the patient died 9 years later from an overwhelming postsplenectomy infection (OPSI). This report suggests that the presence of the amount of retained splenic tissue transplanted in this case after splenectomy ultimately provides relatively ineffective protection against OPSI in congenital osteopetrosis.
Subject(s)
Osteopetrosis/congenital , Pneumococcal Infections/etiology , Sepsis/etiology , Spleen/transplantation , Splenectomy , Adolescent , Humans , Male , Osteopetrosis/surgery , Postoperative Complications , Spleen/pathology , Transplantation, AutologousABSTRACT
The eyes of 7 rabbits with clinical megaloglobus, selected from a large colony, were studied with slit-lamp microscopy, gonioscopy, indirect ophthalmoscopy and tonometry. Selected light and scanning electron microscopy was also performed. There were 11 glaucomatous eyes among the 7 rabbits: gonioscopy demonstrated open iridocorneal angles with absence of pectinate fibres. Incomplete cleavage of the iridocorneal angles in glaucomatous eyes was noted histologically. Because of the similarity of the iridocorneal angles of glaucomatous rabbit eyes with those of human eyes with congenital glaucoma, these rabbits may serve as an experimental model in the understanding and management of certain types of human glaucoma.
