Envolvimento pulmonar na síndrome de Sweet paraneoplásica / Pulmonary involvement in paraneoplastic Sweet's syndrome

Síndrome de Sweet (dermatose neutrofílica febril aguda) é caracterizada por lesões cutâneas inflamatórias acompanhadas por febre, leucocitose e mal-estar, devendo ser reconhecida por hematologistas, já que freqüentemente é paraneoplásica. O envolvimento sistêmico pode estar presente e o comprometimento pulmonar, apesar de raro, tem sido reportado na forma de infiltração pulmonar bilateral, bronquiolite obliterante e derrame pleural. Há infiltração neutrofílica densa na histologia. Apresentamos o caso de uma paciente com leucemia mielóide crônica que desenvolveu a síndrome de Sweet com infiltrações pulmonares não infecciosas, as quais não foram responsivas à antibioticoterapia, porém mostraram melhora clínica com a corticoterapia.

Sweet's syndrome (acute febrile neutrophilic dermatosis) is characterized by inflammatory skin lesions accompanied by fever, leukocytosis and malaise, it should be recognized by hematologists, because it can be a paraneoplastic manifestation. Systemic involvement may be present and lung lesions, despite of the rarity, have been reported in the form of bilateral pulmonary infiltrations, bronchiolitis obliterans and pleural effusion. Histopathology shows dense neutrophilic infiltrates. We present a patient with chronic myeloid leukemia who developed Sweet's syndrome with bilateral pulmonary infiltrations, which were non-responsive to antibiotics but showed clinical improvement on steroid therapy.

Pseudo-Meigs' syndrome associated to renal pelvis tumor.

INTRODUCTION: Pseudo-Meigs' syndrome is associated with tumors different from the benign ovary tumor, but it has never been described in association to transitional cell carcinoma. CASE REPORT: A female 73 year-old patient presenting pleural effusion nonmetastatic associated with renal pelvis transitional cell carcinoma that resolved and did not recur after radical nephroureterectomy. COMMENTS: Renal pelvis transitional cell carcinoma can result in the Pseudo-Meigs' syndrome. Although being a rare clinical entity, the identification of such syndrome can result in an accurate diagnosis, leading to an efficient surgical treatment, without comorbidity for the patient.

Pseudo-Meigs' syndrome associated to renal pelvis tumor

INTRODUCTION: Pseudo-Meigs' syndrome is associated with tumors different from the benign ovary tumor, but it has never been described in association to transitional cell carcinoma. CASE REPORT: A female 73 year-old patient presenting pleural effusion nonmetastatic associated with renal pelvis transitional cell carcinomathat resolved and did not recur after radical nephroureterectomy. COMMENTS: Renal pelvis transitional cell carcinoma can result in the Pseudo-Meigs' syndrome. Although being a rare clinical entity, the identification of such syndrome can result in an accurate diagnosis, leading to an efficient surgical treatment, without comorbidity for the patient.