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1.
Article in Russian | MEDLINE | ID: mdl-1334306

ABSTRACT

The authors studied the effect of the drug emoxypin on the brain functional asymmetry (A) in 36 patients with craniocerebral trauma attended by occurrence of focal traumatic injuries (FTI) to the brain (experimental group). The control group consisted of 61 patients who received the traditional intensive therapy for FTI (isolated brain contusion of moderate and severe degree, intracerebral hematomas measuring 30-50 cm3 in volume in the contusion focus). Favorable changes of the brain FA indices in the individual asymmetry profiles were noted, respectively, in 76.7% and 40.9% of patients given and not given emoxypin. Complete normalization of brain FA indices by the 25th-30th day after the beginning of treatment was recorded in 60.9% of patients in the control group and in 37% of those in the experimental group. The dynamics of individual asymmetry profiles in patients with FTI provides evidence that emoxypin improves the attention, mental efficiency, memory capacity, and selectivity of mnemonic processes.


Subject(s)
Antioxidants/therapeutic use , Brain Injuries/drug therapy , Dominance, Cerebral/drug effects , Picolines/therapeutic use , Brain Concussion/drug therapy , Brain Concussion/physiopathology , Brain Injuries/physiopathology , Cerebral Hemorrhage/drug therapy , Cerebral Hemorrhage/physiopathology , Critical Care , Dominance, Cerebral/physiology , Drug Evaluation , Hematoma/drug therapy , Hematoma/physiopathology , Humans
2.
Article in Russian | MEDLINE | ID: mdl-2781937

ABSTRACT

Individual functional brain asymmetry profiles were different in epileptic patients and healthy individuals. The patients displayed reduced from 39.6% to 17.8% incidence of left profile and increased incidence of combined profile (from 60.4% to 81.5%). The relationship of functional asymmetry profiles to sex, lateralization of epileptic focus and clinical course of the disease was described, the regularities of the profiles' changes in the course of the disease analyzed.


Subject(s)
Brain/physiopathology , Epilepsy/physiopathology , Adolescent , Adult , Electroencephalography , Female , Functional Laterality , Humans , Male , Middle Aged
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