ABSTRACT
BACKGROUND: This study aimed to examine the long-term functional results of patients with isolated discrete subaortic stenosis who underwent subaortic membrane resection and myectomy, using transthoracic M-mode echocardiography and 2D speckle-tracking echocardiography. METHODS: Twenty patients operated for isolated discrete subaortic stenosis and 31 controls were included in the study. Patients underwent subaortic membrane resection and myectomy. During the long-term follow up, patients were evaluated with transthoracic M-mode echocardiography and 2D speckle-tracking echocardiography for functional assessment. RESULTS: The mean age at operation and mean duration of follow up was 8.1±5.6 years and 7.2±3.3 years, respectively. Interventricular septal thickness at diastole (0.9±0.1 vs. 0.8±0.1 cm, P = 0.001), ejection time (285.7±26.2 vs. 261.2±24.3 msec, P = 0.001), and aortic strain (15.6±3.7 vs. 10.5±4.0, P < 0.001) were significantly higher in patients. On the other hand, ejection fraction (64.9±6.1 vs. 75.1±5.4 %, P < 0.001), fractional shortening (35.0±5.1 vs. 43.7±5.1, P < 0.001), and corrected velocity circumferential fiber shortening (0.12±0.02 vs. 0.17±0.03, P < 0.001) were significantly lower, when compared with the controls. Longitudinal strain value significantly differed among the groups, with patients having significantly lower strain (18.8±1.8 vs. 20.1±2.1, P = 0.021). CONCLUSION: In patients operated for isolated discrete subaortic stenosis, aortic gradient seems to continue in the long-term, with the persistence of low longitudinal strain.
Subject(s)
Discrete Subaortic Stenosis/physiopathology , Echocardiography/methods , Stroke Volume/physiology , Vascular Stiffness/physiology , Vascular Surgical Procedures/methods , Adolescent , Child , Discrete Subaortic Stenosis/diagnosis , Discrete Subaortic Stenosis/surgery , Female , Follow-Up Studies , Humans , Male , Recurrence , Reoperation , Retrospective Studies , Time Factors , Treatment OutcomeABSTRACT
BACKGROUND: The aim of this retrospective study is to determine the correlation between preoperative CRP levels and the early renal dysfunction after cardiac surgery. METHODS: From January 2012 to December 2013, values for preoperative CRP were available for 546 unselected patients undergoing cardiac operations. CRP was used to divide this cohort in two groups: a normal CRP levels group (Group I) of 432 patients with CRP of less than 0.5 mg/dL, and a high CRP levels group (group II) of 114 patients with a CRP of 0.5 mg/dL or more. RESULTS: Median CRP preoperative values were significantly different in the group II (2.49±1.03 mg/dL) than in the group I (0.32±0.14 mg/dL; P < 0.0001). Median CRP postoperative values were significantly different in the group I (17.62±2.99) than in the group II (23.13±3.01; P < 0.0001). Preoperative levels of serum blood urea nitrogen (BUN), creatinine and CrCl were not significantly different between group I and group II. Postoperative levels of BUN, Cr and CrCl between the two groups were not significantly different. CONCLUSIONS: The early Cr and CrCl levels after surgery are not significantly different in group I and group II. The early renal function after CABG is not correlated with the preoperative CRP levels.
