ABSTRACT
Metastatic disease is one of the most common causes of calcified nodules in the lung or liver. The incidence of calcified metastasis mainly to the lung and liver is high at the initial presentation in patients with medullary thyroid carcinoma. Synchronous calcified metastasis in the lung and liver is reported for the first time. The diagnosis of medullary thyroid carcinoma may be evident from the synchronous presence of miliary calcified nodules in two different sites if they are associated with high concentrations of serum markers.
Subject(s)
Carcinoma, Medullary/pathology , Liver Neoplasms/secondary , Lung Neoplasms/secondary , Thyroid Neoplasms/pathology , Adult , Calcinosis/pathology , Carcinoma, Medullary/diagnostic imaging , Humans , Liver Neoplasms/diagnostic imaging , Lung Neoplasms/diagnostic imaging , Male , Neoplasm Metastasis , Radiography , Thyroid Neoplasms/diagnostic imagingABSTRACT
We report a six-year-old boy who presented with swelling of the forehead, and had calvarial tuberculosis, a rare form of tuberculous osteitis.
Subject(s)
Frontal Bone , Mycobacterium tuberculosis/isolation & purification , Tuberculosis, Osteoarticular/diagnosis , Tuberculosis, Osteoarticular/drug therapy , Antitubercular Agents/therapeutic use , Biopsy, Needle , Child , Drug Therapy, Combination , Follow-Up Studies , Humans , Male , Osteomyelitis/diagnosis , Tomography, X-Ray Computed , Treatment OutcomeABSTRACT
Congenital granular cell tumors of the gingiva (synonyms: congenital myoblastoma, congenital epulis) originate from the alveolar ridge in newborns. They are rare granular-cell tumors with benign histology. The main differential diagnosis is epignathus (oral teratoma). Early surgical excision is recommended due to a risk of airway obstruction and difficulty feeding.
Subject(s)
Gingival Neoplasms/congenital , Gingival Neoplasms/surgery , Granular Cell Tumor/congenital , Granular Cell Tumor/surgery , Gingival Neoplasms/pathology , Granular Cell Tumor/pathology , Humans , Infant, Newborn , MaleABSTRACT
BACKGROUND: Angiomyolipomas are tumors composed of adipose tissue, blood vessels and smooth muscle. Although renal angiomyolipomas are well known, cutaneous tumors have been described only recently. HMB-45 reactivity, reported for renal angiomyolipomas, has been suggested as a useful tool in differential diagnosis. OBJECTIVE: Two cases of cutaneous angiomyolipoma are described and investigated for HMB-45 reactivity. METHODS: Conventional histochemical and immunohistochemical methods were used. RESULTS: Immunohistochemical analysis showed no reactivity for HMB-45 antibody. CONCLUSION: We conclude that, unlike renal angiomyolipomas, HMB-45 reactivity is not helpful in differentiating cutaneous angiomyolipomas.
