ABSTRACT
To find common factors for colonic-neoplasias and skin-tags, 157 inpatients, who consecutively had a coloscopy because of intestinal complaints, were intensively examined dermatologically. Regression-analyses showed that the number of colonic polyps were age- (p = 3 x 10(-8)) and sex-dependent (1.9 x 10(-2)) and skin-tags had no influence on the number of colonic polyps. The size of colonic polyps also showed a clear age dependency (p = 3 x 10(-8)). The number of skin-tags were dependent on weight (p = 9 x 10(-3)) and age (p = 1.3 x 10(-2)), its size on the interaction of sex and triglyceride-levels (p = 3 x 10(-8)). Discriminant-analyses identified the following factors as important: age and triglyceride-concentration to recognize a patient with colonic polyps; age, positive Haemoccult-test and number of skin-tags to recognize a patient with tubulovillous adenomas or colonic carcinomas. The essential common factor of colonic polyps and skin-tags was the age. For the recognition of a patient with colonic polyps the age was the most essential factor, skin-tags, on the contrary, were unimportant. The association between colonic polyps and skin-tags therefore was merely an effect of age.
Subject(s)
Colonic Neoplasms/etiology , Colonic Polyps/etiology , Fibroma/etiology , Neoplasms, Multiple Primary/etiology , Paraneoplastic Syndromes/etiology , Skin Neoplasms/etiology , Age Factors , Cholesterol/blood , Female , Humans , Male , Middle Aged , Occult Blood , Risk Factors , Triglycerides/bloodABSTRACT
In a representative sample population of 421 two-year-old Frankfurt children studied for vitamin-D nutritional status, only one case of subclinical rickets was discovered. 93.3% of the children have been a regular vitamin-D supplements during the first 12 month of life, but only 32.7% of them continued to receive the supplement beyond the age of one year. Risk groups were not identified, neither with regard to ethnic groups, nor smaller vitamin-D doses, or any other aspect.
Subject(s)
Vitamin D/blood , Child, Preschool , Female , Germany, West , Humans , Infant , Male , Rickets/prevention & control , Vitamin D/administration & dosageABSTRACT
Hair zinc concentration was measured in centimeter sections of hair strands obtained from 17 mothers after delivery of newborn infants with spina bifida cystica. Thirty unselected healthy mothers and their normal newborn infants served as the controls. In the mothers of the diagnosis group, mean hair zinc concentration (216.2 microgram/g; SD = 43.2) was significntly higher than in the controls (181.6 microgram/g; SD = 31.4); it increased during pregnancy, whereas it decreased in the controls during the same time, and it was positively correlated to the hair zinc concentration of the newborn infants, while no such correlation could be detected in the controls. In the diagnosis group, mean birth weight (2808 g; SD = 382) and length (48.5 cm; SD = 2.3) of the term infants were significantly lower than in the control group (3310 g; SD = 382, and 51.2 cm; SD = 1.9, respectively). It is speculated that the differences in the zinc and growth parameters between the diagnosis and control group indicate an abnormality of zinc availability or metabolism in the mothers of infants with spina bifida.
