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Clin Nucl Med ; 19(3): 197-203, 1994 Mar.
Article in English | MEDLINE | ID: mdl-8033467

ABSTRACT

The authors present comparative triple-phase bone scan findings in three cases of histologically proven aggressive fibromatosis both before (initial evaluation) and after radiation therapy. The purpose of the study was to compare triple-phase bone scan findings in aggressive fibromatosis both before and after radiation therapy and to determine whether any additional physiological information could be obtained. Before radiation therapy, the triple-phase bone scintigraphy demonstrated increased flow and radiotracer pooling in the areas of tumors on dynamic flow and immediate blood pool images, respectively. However, the delayed static images demonstrated variable radiotracer uptake. When compared to preradiation therapy triple-phase bone scan, decreased vascularity was well demonstrated in all three patients after radiation therapy. In addition, it also provided information regarding the changes in the size and extent of tumor, noninvaded underlying bone, and remainder of the skeleton. This additional information can be particularly useful in patients with equivocal or questionable histologic diagnosis especially from small, unrepresentative biopsies.


Subject(s)
Bone Neoplasms/diagnostic imaging , Bone Neoplasms/secondary , Bone and Bones/diagnostic imaging , Fibromatosis, Abdominal/diagnostic imaging , Fibromatosis, Abdominal/radiotherapy , Adult , Biopsy , Bone and Bones/pathology , Female , Fibromatosis, Abdominal/pathology , Humans , Magnetic Resonance Imaging , Male , Middle Aged , Radionuclide Imaging , Radiotherapy Dosage , Technetium Tc 99m Medronate/analogs & derivatives , Time Factors
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