Subject(s)
Sclera , Trabeculectomy , Glaucoma/surgery , Humans , Intraocular Pressure , Mitomycin , Postoperative Complications , Treatment OutcomeABSTRACT
Primary angle closure in a high myopic patient is rare. Here is presented a report of one such patient who presented with acute primary angle closure in one eye. Conservative management followed by laser iridotomy was effective in the treatment of this patient.
Subject(s)
Glaucoma, Angle-Closure/complications , Glaucoma, Angle-Closure/diagnosis , Myopia/complications , Adult , Female , Glaucoma, Angle-Closure/therapy , HumansSubject(s)
Glaucoma/pathology , Optic Nerve Diseases/pathology , Optic Nerve/pathology , Pupil Disorders/etiology , Female , Humans , MaleSubject(s)
Blindness/prevention & control , Eye Diseases/prevention & control , Global Health , Mass Screening , Refractive Errors , Adolescent , Child , Child Welfare , Female , Humans , Male , World Health OrganizationABSTRACT
Diabetes is a worldwide medical problem and is a significant cause of morbidity and mortality. It has considerable impact on both the patient and the society because it typically affects individuals in their most productive years. It is also one of the leading causes of blindness and visual impairment. A person with diabetes has 25 times the risk of blindness compared to a non-diabetic. This article reviews the variety of ways in which the eye and its adnexa can be involved in diabetes mellitus.
Subject(s)
Diabetes Complications/pathology , Diabetic Retinopathy/pathology , Eye Diseases/pathology , Diabetes Complications/physiopathology , Diabetic Retinopathy/physiopathology , Eye Diseases/physiopathology , HumansABSTRACT
Ophthalmomyiasis is a rare condition. Here two such patients, one of 70-year-old male farmer with history of neglected trauma presented with painful swelling with sinus of right orbit and the second one of 65-year-old female destitute who presented with fungating mass near the medial canthus of left eye with pain and bleeding are reported. All the maggots were removed after applying ether.
Subject(s)
Eye Infections, Parasitic/diagnosis , Myiasis/diagnosis , Aged , Animals , Eye Infections, Parasitic/physiopathology , Female , Humans , Larva/parasitology , Male , Myiasis/physiopathologyABSTRACT
Glaucoma is the second largest blinding disorder, after cataract, affecting about 67 million people worldwide. In India about 1.5 million people are blind due to glaucoma. Primary open angle glaucoma is the major sub-type of glaucoma affecting all ages and is genetically complex. Myocilin and optineurin are two different genes that have been implicated for primary open angle glaucoma. This review is focused on the studies being conducted in India on primary open angle glaucoma to identify the molecular defects and new directions undertaken using bioinformatic approaches towards a better understanding of the disease.
Subject(s)
Computational Biology , Glaucoma, Open-Angle/genetics , Vision Disorders/etiology , Blindness/etiology , Blindness/genetics , Cell Cycle Proteins , Chromosomes, Human, Pair 10/genetics , Cytoskeletal Proteins/genetics , Eye Proteins/genetics , Glaucoma, Open-Angle/classification , Glaucoma, Open-Angle/complications , Glycoproteins/genetics , Humans , India , Membrane Transport Proteins , Transcription Factor TFIIIA/genetics , Vision Disorders/geneticsABSTRACT
BACKGROUND: The purpose of the present paper was to report the spectrum of primary malignant tumours of eye and adnexa at BP Koirala Institute of Health Sciences, Nepal, from 1995 to 2000. METHODS: A retrospective study of medical records with histopathological confirmation of malignant tumours of the eye and adnexa was done for the years 1995-2000. A total of 116 consecutive medical records from the Department of Pathology at BP Koirala Institute of Health Sciences were retrieved. All those patients with primary ophthalmic malignancies were included and non-malignant cases were excluded. RESULTS: There were 80 patients of which 39 (48.8%) were male and 41 (51.2%) were female. Four patients had bilateral involvement. The most common malignancy was retinoblastoma (45.2%), followed by basal cell carcinoma (22.6%). CONCLUSION: Retinoblastoma is the most common eye cancer. The incidence of melanomas is correspondingly lower than that reported in the West. The present pilot study, the first of its kind, will lay the foundation for the monitoring of the future pattern of ophthalmic malignancies in Nepal and provide a basis for comparison elsewhere.
Subject(s)
Eye Neoplasms/epidemiology , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Carcinoma, Basal Cell/epidemiology , Carcinoma, Squamous Cell/epidemiology , Child , Child, Preschool , Eye Neoplasms/pathology , Female , Humans , Infant , Male , Middle Aged , Neoplasm Invasiveness , Nepal/epidemiology , Optic Nerve/pathology , Orbit/pathology , Pilot Projects , Retinoblastoma/epidemiology , Retinoblastoma/pathology , Retrospective StudiesABSTRACT
The case of a 40-year-old female patient with choroidal melanoma with secondary glaucoma presenting as a painful blind right eye is reported. Liver metastasis was detected by ultrasonography. The choroidal tumor measured 2 x 2.1 x 1.5 cm; histopathology showed that it was of the spindle cell (spindle A) variety. Such tumors are rare in non-white races and secondary glaucoma is an uncommon presentation.
Subject(s)
Choroid Neoplasms/complications , Glaucoma/etiology , Melanoma/complications , Adult , Choroid Neoplasms/diagnosis , Female , Humans , Liver Neoplasms/diagnostic imaging , Liver Neoplasms/secondary , Melanoma/diagnosis , Nepal , UltrasonographyABSTRACT
Rhinosporidiosis is endemic in India, Sri Lanka, and parts of East Africa and South America; sporadic cases are reported in other countries. We report on five patients from eastern Nepal with oculosporidiosis. The conjunctiva was involved in two patients and the lacrimal sac was involved in three patients; treatment was by simple total excision of the conjunctivalgrowth (patients with conjunctival involvement) and by dacryocystectomy (patients with lacrimal sac involvement). This is the second case report from Nepal.