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1.
J Pharm Bioallied Sci ; 16(Suppl 2): S1498-S1504, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38882717

ABSTRACT

The aim of this study is to determine the stress in short implants loaded with varying crown heights using a 3D finite element analysis. A total of three mandibular sectional bone blocks depicting the mandibular left first molar region were modeled. Each block carried Bicon implants of the same size and was designated B1, B2, and B3. The implant- crown ratio is 1:1.5, 1:2.5, and 1:3 respectively. The loading protocol included axial and oblique loads. The von Misses' equivalent stresses at the implant-bone interface were evaluated. Intergroup comparison was determined using one-way ANOVA analysis, and P values were calculated. Under an axial load of 600N, the models B1, B2, and B3 do not show any statistically significant P-values at the crestal module of the implant, abutment, and bone, whereas in crowns, the P-values were highly significant. Under an oblique load of 225 N at 0°, 45°, and 90°, model B3 showed the highest values in the crestal module, abutment, and crown. Based on the intergroup comparison and P value the study concluded that the variance in the crown height does not affect the bone and therefore microfracture of the bone and failure of osseointergration is not likely.

2.
J Pharm Bioallied Sci ; 16(Suppl 2): S1154-S1160, 2024 Apr.
Article in English | MEDLINE | ID: mdl-38882752

ABSTRACT

This study aims to determine the efficient concentration of Sapindus mukorossi that can be used as a denture cleanser. 60 heat cure denture base resin specimens of dimensions 10*10*2 mm were fabricated. Among these, 30 were fabricated by compression moulding technique and the remaining 30 by an injection moulding technique. The samples inoculated with Candida albicans and Streptococcus mutans were subjected to denture cleansing protocols using a medicinal herbal extract from the Sapindus mukorossi, at various concentrations [15%, 20%, and 25%]. The colony-forming unit [CFU] values were evaluated using a microprocessor colony counter. The statistical analysis was performed. The intragroup comparison showed a statistically significant difference between all groups except the compression moulded samples inoculated with Streptococcus mutans. The intergroup comparison revealed no statistically significant differences between the compared groups. The reduction in CFU values is evident in the effective anti-microbial activity of Sapindus mukorossi. A concentration of 25% Sapindus mukorossi solution showed the greatest efficiency. The maximum anti-microbial activity was observed against Candida albicans in a 25% concentration of Sapindus mukorossi. Among all, injection moulded samples showed better results.

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