ABSTRACT
The purpose of this study is to determine the efficacy and safety of 595-nm pulsed dye laser (PDL) for port wine stains (PWS) treatment in Vietnamese patients. The study also analyzed the association between the response to treatment and the characteristics of patients and treatment regimens. Parallelly, the study contributed to further optimal treatment sessions for different subjects based on the data collected. One hundred twenty-five patients who underwent 595-nm PDL to treat PWS were included in the study, in which data from 124 patients was retrospectively analyzed. Data on demographic characteristics of patients, treatment regimens, and clinical improvement were collected. SPSS version 25 was used to analyze the relationship between associated factors and the response rate. The overall response rate of Vietnamese patients who had Fitzpatrick skin classification type III and IV was 73.4%. Age, gender, treatment sessions, and lesion positions were generally not associated with the response rate. The lesion grade was the sole element that affected the clinical improvement. The lesion grade 1 had the best response (100%) even after a short duration of treatment (six to ten treatments). Lesion grade 4 demanded over 16 treatments to reach > 60% of improvement. The lesion grades 1 and 2 could be blanched with regimen < 10 treatments while regimens exceeding 15 treatments should be carefully considered for lesions at grade 3 after evaluating associated conditions. Lesions at grade 4 demanded ≥ 16 treatments to reach acceptable outcomes. These results could help physicians establish a reasonable treatment strategy for patients.
Subject(s)
Lasers, Dye , Port-Wine Stain , Humans , Retrospective Studies , Southeast Asian PeopleABSTRACT
Based on the factors of the Theory of Planned Behaviour (TPB), the Health Belief Model (HBM), and the DOSPERT scale, used to measure general risk-taking behaviour, a combined model has been developed for investigating tourists' intentions to implement protective measures against the coronavirus disease 2019 (COVID-19). The purpose of the study is to formulate a model that Swiss tourism practitioners can use to understand tourists' decision-making regarding the acceptance and proper implementation of non-pharmaceutical interventions (NPIs). A large-scale cross-sectional population study that is representative for the Swiss population has been designed to validate the model (N = 1,683; 39% response rate). In our empirical investigation, a simple regression analysis is used to detect significant factors and their strength. Our empirical findings show that the significant effects can be ordered regarding descending effect size from severity (HBM), attitude (TPB), perceived behavioural control (TPB), subjective norm (TPB), self-efficacy (HBM), and perceived barriers (HBM) to susceptibility (HBM). Based on this information, intervention strategies and corresponding protective measures were linked to the social-psychological factors based on an expert workshop. Low-cost interventions for tourists (less time, less money, and more comfort), such as the free provision of accessories (free mask and sanitizers) or free testing (at cable cars), can increase the perceived behavioural control and lower the perceived barriers and thus increase the acceptance of this protective measure.
ABSTRACT
BACKGROUND: Aging is an increasing concern of modern society, particularly facial ageing. In recent years, the microinjection technique has increasingly been emphasised as a skin rejuvenation strategy. Hyaluronic acid (HA) plays an important role in the hydration of the extracellular space and can thus improve skin hydration, firmness and viscoelastic properties. AIM: To evaluate the efficacy and safety of HA microinjection in skin rejuvenation. METHODS: We enrolled thirty participants underwent three sessions of HA microinjection involving multiple injections in the face or back of the hands at 2-week intervals. The aesthetic outcomes were assessed at baseline and after 2, 4 and 8 weeks. Clinical evaluation was based on the Global Aesthetic Improvement Scale (GAIS) and the Wrinkle Severity Rating Scale (WSRS). RESULTS: Evaluation of photographs from 2, 4 and 8 weeks revealed significant clinical improvement in the brightness, texture and wrinkling of the skin. Analysis of the GAIS and WSRS scores revealed statistically significant results after 2 months. CONCLUSION: Most of the participants felt satisfied with the treatment (93.3%).