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1.
Appl Radiat Isot ; 88: 185-9, 2014 Jun.
Article in English | MEDLINE | ID: mdl-24365468

ABSTRACT

The activity in accelerator development for accelerator-based BNCT (AB-BNCT) both worldwide and in Argentina is described. Projects in Russia, UK, Italy, Japan, Israel, and Argentina to develop AB-BNCT around different types of accelerators are briefly presented. In particular, the present status and recent progress of the Argentine project will be reviewed. The topics will cover: intense ion sources, accelerator tubes, transport of intense beams, beam diagnostics, the (9)Be(d,n) reaction as a possible neutron source, Beam Shaping Assemblies (BSA), a treatment room, and treatment planning in realistic cases.


Subject(s)
Boron Neutron Capture Therapy/instrumentation , Particle Accelerators/instrumentation , Radiometry/instrumentation , Equipment Design , Equipment Failure Analysis , Internationality , Technology Assessment, Biomedical
2.
Appl Radiat Isot ; 67(7-8 Suppl): S266-9, 2009 Jul.
Article in English | MEDLINE | ID: mdl-19376714

ABSTRACT

In this work we describe the present status of an ongoing project to develop a tandem-electrostatic-quadrupole (TESQ) accelerator facility for accelerator-based (AB) BNCT at the Atomic Energy Commission of Argentina in Buenos Aires. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the (7)Li(p,n)(7)Be reaction slightly beyond its resonance at 2.25 MeV. These are the specifications needed to produce sufficiently intense and clean epithermal neutron beams, based on the (7)Li(p,n)(7)Be reaction, to perform BNCT treatment for deep-seated tumors in less than an hour. An electrostatic machine is the technologically simplest and cheapest solution for optimized AB-BNCT. The machine being designed and constructed is a folded TESQ with a high-voltage terminal at 1.2 MV intended to work in air. Such a machine is conceptually shown to be capable of transporting and accelerating a 30 mA proton beam to 2.4 MeV. The general geometric layout, its associated electrostatic fields, and the acceleration tube are simulated using a 3D finite element procedure. The design and construction of the ESQ modules is discussed and their electrostatic fields are investigated. Beam transport calculations through the accelerator are briefly mentioned. Likewise, work related to neutron production targets, strippers, beam shaping assembly and patient treatment room is briefly described.


Subject(s)
Boron Neutron Capture Therapy/instrumentation , Particle Accelerators , Argentina , Biophysical Phenomena , Brain Neoplasms/radiotherapy , Facility Design and Construction , Humans , Static Electricity
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