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1.
Sci Rep ; 12(1): 17859, 2022 10 25.
Article in English | MEDLINE | ID: mdl-36284133

ABSTRACT

Worldwide, over 250 million children under 5 years do not reach their developmental potential due to several causes, including malnutrition. In Cambodia, the prevalence of stunting and wasting among children remains high. This prospective cohort study aimed to assess acquisition of motor and cognitive developmental milestones in early childhood and their associations with stunting and wasting. Children aged from 0 to 24 months were recruited from three provinces in Cambodia and followed up to seven times from March 2016 to June 2019, until their 5 years. Data collection included anthropometry and developmental milestones. Seven motor and seven cognitive milestones were evaluated using the Cambodian Development Milestone Assessment Tool. Associations were assessed with parametric survival models. Hazard ratios (HR) below 1 stood for lower probabilities for achieving developmental milestones. Data were available for 7394 children. At 12 months, the prevalence of stunting and wasting were 23.7% and 9.6% respectively. Both were consistently associated with delays in most motor and cognitive milestones. Stunting was strongly associated with delays in gross motor milestones (HR < 0.85; p < 0.001). Wasting was more strongly associated with delays in fine motor development and most cognitive milestones (HR < 0.75; p < 0.001). Promoting nutritional programs in the first 1000 days to prevent malnutrition is essential to further the optimal growth and motor and cognitive development of Cambodian children.


Subject(s)
Growth Disorders , Malnutrition , Child , Humans , Child, Preschool , Infant , Prospective Studies , Growth Disorders/epidemiology , Growth Disorders/etiology , Malnutrition/epidemiology , Malnutrition/complications , Cohort Studies , Cachexia , Prevalence , Asian People
2.
Nutrients ; 11(7)2019 Jul 05.
Article in English | MEDLINE | ID: mdl-31284369

ABSTRACT

Even though limited evidence is available, the relationship between morbidity and under-nutrition among children under-five is likely to be a strong two-way association. This study aims to explore this vicious cycle by employing longitudinal data of four periods within a 24 month follow-up, whereby morbidity was captured between two subsequent anthropometric measures. Malnutrition was classified according to z-scores of anthropometric measures and morbidity by number of sick days experienced inbetween. Mixed-effects models were used to assess this relation, where dependency of morbidity and nutritional status were interchanged; models were adjusted for province, age, gender, wealth index score, maternal education level, diet, and Water, Sanitation, and Hygiene indicators. Stunting and wasting prevalences were 29.9% and 8.9%, respectively, where 21.3% of the children hadmultiple anthropometric failures. Children identified as wasted were 35% more likely to experience prolonged illness periods (OR: 1.35, 95% CI: 1.02-1.56). Those experiencing high proportion of sick days were found to be 64% more likely to become stunted (OR: 1.64, 95% CI: 1.18-2.29). This study suggests that the link between wasting and stunting could be partly explained by acute illness, where wasting increases the likelihood of prolonged epiosed of illness, which increases the risk of stunting.


Subject(s)
Child Nutrition Disorders/epidemiology , Child Nutritional Physiological Phenomena , Growth Disorders/epidemiology , Malnutrition/epidemiology , Nutritional Status , Age Factors , Cambodia/epidemiology , Child Development , Child Nutrition Disorders/diagnosis , Child Nutrition Disorders/physiopathology , Child, Preschool , Female , Growth Disorders/diagnosis , Growth Disorders/physiopathology , Humans , Infant , Infant Nutritional Physiological Phenomena , Longitudinal Studies , Male , Malnutrition/diagnosis , Malnutrition/physiopathology , Prevalence , Risk Assessment , Risk Factors , Time Factors
3.
Food Nutr Bull ; 34(2 Suppl): S8-16, 2013 Jun.
Article in English | MEDLINE | ID: mdl-24049992

ABSTRACT

BACKGROUND: To further reduce stunting in Southeast Asia, a rapidly changing region, its main causes need to be identified. OBJECTIVE: Assess the relationship between different causes of stunting and stunting prevalence over time in Southeast Asia. METHODS: Review trends in mortality, stunting, economic development, and access to nutritious foods over time and among different subgroups in Southeast Asian countries. RESULTS: Between 1990-2011, mortality among under-five children declined from 69/1,000 to 29/1,000 live births. Although disease reduction, one of two direct causes of stunting, has played an important role which should be maintained, improvement in meeting nutrient requirements, the other direct cause, is necessary to reduce stunting further. This requires dietary diversity, which is affected by rapidly changing factors: economic development; urbanization, giving greater access to larger variety of foods, including processed and fortified foods; parental education; and modernizing food systems, with increased distance between food producers and consumers. Wealthier consumers are increasingly able to access a more nutritious diet, while poorer consumers need support to improve access, and may also still need better hygiene and sanitation. CONCLUSIONS: In order to accelerate stunting reduction in Southeast Asia, availability and access to nutritious foods should be increased by collaboration between private and public sectors, and the Association of Southeast Asian Nations (ASEAN) can play a facilitating role. The private sector can produce and market nutritious foods, while the public sector sets standards, promotes healthy food choices, and ensures access to nutritious foods for the poorest, e.g, through social safety net programs.


Subject(s)
Growth Disorders/prevention & control , Asia, Southeastern/epidemiology , Child Mortality , Child Nutritional Physiological Phenomena , Child, Preschool , Diet , Food/economics , Food Quality , Food, Fortified , Growth Disorders/epidemiology , Health Education , Humans , Income , Infant , Infant, Newborn , Malnutrition/prevention & control , Nutritional Requirements , Parents/education
4.
Food Nutr Bull ; 34(2 Suppl): S62-71, 2013 Jun.
Article in English | MEDLINE | ID: mdl-24049997

ABSTRACT

BACKGROUND: The prevalence of micronutrient deficiencies in Cambodia is among the highest in Southeast Asia. Fortification of staple foods and condiments is considered to be one of the most cost-effective strategies for addressing micronutrient deficiencies at the population level. The Government of Cambodia has recognized the importance of food fortification as one strategy for improving the nutrition security of its population. OBJECTIVE: This paper describes efforts under way in Cambodia for the fortification of fish sauce, soy sauce, and vegetable oil. METHODS: Data were compiled from a stability test of Cambodian fish sauces fortified with sodium iron ethylenediaminetetraacetate (NaFeEDTA); analysis of fortified vegetable oils in the Cambodian market; a Knowledge, Attitudes, and Practices (KAP) study of fortified products; and food fortification program monitoring documents. RESULTS: At different levels of fortification of fish sauce with NaFeEDTA, sedimentation and precipitation were observed. This was taken into consideration in the government-issued standards for the fortification of fish sauce. All major brands of vegetable oil found in markets at the village and provincial levels are imported, and most are nonfortified. CONCLUSIONS: Fish sauce, soy sauce, and vegetable oil are widely consumed throughout Cambodia and are readily available in provincial and village markets. Together with an effective regulatory monitoring system, the government can guarantee that these commodities, whether locally produced or imported, are adequately fortified. A communications campaign would be worthwhile, once fortified commodities are available, as the KAP study found that Cambodians had a positive perception of fortified sauces.


Subject(s)
Ferric Compounds/analysis , Fish Products , Food, Fortified/analysis , Plant Oils/analysis , Soy Foods/analysis , Anemia, Iron-Deficiency/epidemiology , Anemia, Iron-Deficiency/prevention & control , Cambodia/epidemiology , Chemical Precipitation , Cost-Benefit Analysis , Drug Stability , Edetic Acid/analysis , Edetic Acid/chemistry , Ferric Compounds/chemistry , Fish Products/analysis , Food, Fortified/economics , Health Knowledge, Attitudes, Practice , Humans , Micronutrients/deficiency , Nutritional Status , Program Evaluation
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