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J Vet Med Sci ; 76(1): 85-7, 2014 Jan.
Article in English | MEDLINE | ID: mdl-23986117

ABSTRACT

In August 2012, A/chicken/Vietnam/OIE-2215/2012 (H5N2) was isolated from a chicken in a live bird market (LBM) in Northern Vietnam. Intravenous pathogenicity test revealed that this virus is highly pathogenic in chickens. The PA, HA, NP and M, PB2 and NA, and PB1 and NS genes of the isolate were phylogenetically closely related to those of A/duck/Vietnam/OIE-2202/2012 (H5N1) of clade 2.3.2.1, A/chicken/Vietnam/OIE-1611/2012 (H9N2) and A/chicken/Vietnam/OIE-2468/2012 (H9N2), respectively. All of these viruses were isolated from birds in LBMs in the same province. These results indicate that A/chicken/Vietnam/OIE-2215/2012 (H5N2) is a genetic reassortant and that surveillance of avian influenza in LBMs and stamping out policy are essential for the eradication of highly pathogenic avian influenza viruses from Asia.


Subject(s)
Chickens , Influenza A Virus, H5N2 Subtype/genetics , Influenza in Birds/virology , Phylogeny , Reassortant Viruses/genetics , Amino Acid Sequence , Animals , Base Sequence , Chick Embryo , Molecular Sequence Data , RNA, Viral/chemistry , RNA, Viral/genetics , Sequence Alignment , Sequence Analysis, DNA , Vietnam
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