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Cutis ; 81(2): 127-30, 2008 Feb.
Article in English | MEDLINE | ID: mdl-18441765

ABSTRACT

GOAL: To understand primary cutaneous aspergillosis to better manage patients with the condition. OBJECTIVES: Upon completion of this activity, dermatologists and general practitioners should be able to: 1. Describe risk factors for Aspergillus infection. 2. Identify diagnostic methods for primary cutaneous aspergillosis. 3. Discuss treatment options for primary cutaneous aspergillosis. Primary cutaneous aspergillosis is an uncommon disease in immunocompetent individuals that often affects immunosuppressed hosts. We present the first reported case of primary cutaneous aspergillosis in a solid organ transplant recipient caused by Aspergillus niger. Fruiting bodies were isolated from a necrotic ulcer arising in a surgical wound. Debridement alone failed to resolve the infection, emphasizing the need for early antifungal treatment combined with surgical management of this infection.


Subject(s)
Aspergillosis/diagnosis , Immunocompromised Host , Immunosuppressive Agents/therapeutic use , Kidney Transplantation , Surgical Wound Infection/microbiology , Amphotericin B/therapeutic use , Antifungal Agents/therapeutic use , Aspergillosis/immunology , Aspergillosis/therapy , Debridement , Diagnosis, Differential , Fatal Outcome , Female , Humans , Middle Aged , Surgical Wound Infection/immunology , Surgical Wound Infection/therapy
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