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1.
Med Oral Patol Oral Cir Bucal ; 28(3): e238-e246, 2023 May 01.
Article in English | MEDLINE | ID: mdl-36243995

ABSTRACT

BACKGROUND: In recent years, electric scooters (e-scooter) have emerged as an alternative mode of urban transport due to their availability and effortless use. However, e-scooter-related trauma and injuries, especially to the head, have received wide media coverage and raised public concern about their safety. We aim to determine and compare clinically relevant variables, incidence, and severity between bicycle and e-scooter-related facial fractures and potential protective measures for injury prevention. MATERIAL AND METHODS: This retrospective study comprised all patients admitted to a tertiary trauma center with bicycle or e-scooter-related facial fractures between January 2019 and October 2020. Patient- and injury-related variables, including demographics, injury mechanisms, helmet use, influence of alcohol, types of facial injuries, types of other injuries, given treatment, and hospital stay, were collected, analysed, and compared between bicycle and e-scooter injuries. RESULTS: Altogether 169 patients with facial fractures, 124 bicycle-related injuries (73.4%) and 45 e-scooter-related injuries (26.6%) were included. Alcohol involvement was significantly higher in e-scooter patients (88.9%) than in bicycle patients (31.5%) (p<0.001). Driving under the influence of alcohol was associated with driving without a helmet in both groups (p<0.001). In multivariate analyses, e-scooter accidents were 18 times more likely to occur under the influence of alcohol (OR 17.85, p<0.001) and were more likely to involve collision with a stationary object (OR 3.81, p=0.028). E-scooter patients were significantly younger (OR 0.95, p<0.001) and had significantly more cranial fractures (OR 10.15, p=0.014) than bicycle patients. CONCLUSIONS: Compared with patients in bicycle accidents, facial fracture patients injured in e-scooter accidents are younger, are more likely under the influence of alcohol, and sustain more severe craniofacial skeleton fractures. Our results for both groups of patients advocate stricter adherence to helmet and road safety legislation as well as public education for injury prevention.


Subject(s)
Driving Under the Influence , Skull Fractures , Humans , Retrospective Studies , Bicycling/injuries , Accidents, Traffic , Ethanol
2.
Int J Oral Maxillofac Surg ; 51(1): 91-97, 2022 Jan.
Article in English | MEDLINE | ID: mdl-34175177

ABSTRACT

This study clarified the injury characteristics and occurrence of associated injuries in patients with assault-related facial fractures. Data from 840 assault-related facial fracture patients were included; demographic factors, facial fracture type, associated injuries, alcohol use, and injury mechanisms were recorded. Assault mechanisms most often included combinations of different mechanisms (57.5%) and resulted in the victim falling (50.1%). The perpetrator was most commonly a stranger (52.5%) and acted alone (57.7%). A total of 123 patients (14.6%) had associated injuries, with the most common being traumatic brain injury. Associated injuries occurred most frequently in patients with combined fractures of the facial thirds (24.2%) and upper third fractures (42.9%). The most significant differentiating factors for associated injuries were the number of perpetrators, falling, the use of an offensive weapon, and if the events of the assault remained unknown. In adjusted logistic regression analyses, statistically significant associations with associated injuries were found for age (odds ratio (OR) 1.05, 95% confidence interval (CI) 1.03-1.07; P < 0.001), falling due to the assault (OR 2.87, 95% CI 1.49-5.50; P = 0.002), and upper third facial fractures (OR 6.93, 95% CI 2.06-23.33; P = 0.002). A single punch also caused severe injuries and should therefore not be overlooked, as this can be as dangerous as other assault mechanisms.


Subject(s)
Facial Injuries , Skull Fractures , Accidental Falls , Alcohol Drinking , Facial Bones , Humans , Retrospective Studies
3.
Int J Oral Maxillofac Surg ; 50(4): 463-470, 2021 Apr.
Article in English | MEDLINE | ID: mdl-32994036

ABSTRACT

Current knowledge of blunt cerebrovascular injuries (BCVIs) in craniomaxillofacial fracture (CMF) patients is limited. The purpose of this study was to determine the occurrence of BCVIs in patients with all types of CMF. This retrospective study included CMF patients in a level 1 trauma centre during a 3-year period. Patients who were not imaged with computed tomography angiography and patients with mechanisms other than blunt injury were excluded. The primary outcome variable was BCVI. A total of 753 patients were included in the analysis. A BCVI was detected in 4.4% of the patients screened. BCVIs occurred in 8.7% of cranial fracture patients, 7.1% of combined craniofacial fracture patients, and 3.1% of facial fracture patients. The risk of BCVI was significantly increased in patients with isolated cranial fractures (odds ratio (OR) 2.55, 95% confidence interval (CI) 1.18-5.50; P=0.017), those involved in motor vehicle accidents (OR 3.42, 95% CI 1.63-7.17; P=0.001), and those sustaining high-energy injuries (OR 3.17, 95% CI 1.57-6.40; P=0.001). BCVIs in CMF patients are relatively common in high-energy injuries. However, these injuries also occur in minor traumas. Imaging thresholds should be kept low in this patient population when BCVIs are suspected.


Subject(s)
Cerebrovascular Trauma , Wounds, Nonpenetrating , Cerebrovascular Trauma/diagnostic imaging , Cerebrovascular Trauma/epidemiology , Computed Tomography Angiography , Humans , Mass Screening , Retrospective Studies , Wounds, Nonpenetrating/diagnostic imaging , Wounds, Nonpenetrating/epidemiology
4.
Int J Oral Maxillofac Surg ; 49(11): 1439-1444, 2020 Nov.
Article in English | MEDLINE | ID: mdl-32680807

ABSTRACT

The purpose of this study was to clarify the frequency of missed mandibular fractures and to identify possible predictive factors for missed diagnosis. This was a retrospective study that included patients <20 years of age with a recent mandibular fracture. The outcome variable was missed mandibular fracture, which was determined when a fracture was not suspected or diagnosed during the patient's first assessment in primary healthcare. The primary predictor variable was age group (i.e. children <13 years or teenagers/adolescents aged 13-19 years). The explanatory variables were sex, mechanism of injury, and type of facial facture. Other variables were clinical symptoms and findings. Mandibular fracture was missed at first contact in 27 of 182 patients (14.8%). Fracture was missed significantly more often in patients <13 years than in older patients (33.3% vs. 8.8%, P<0.001). The only significant symptom or clinical finding that was associated with missed fractures was skin wound of the jaw (P=0.009). There was no association between missed fracture and sex or mechanism of injury. Mandibular fractures in children are often missed at the first healthcare contact. Careful examination is necessary in paediatric mandibular injuries, particularly in the youngest age groups. Consultation should be smooth between paediatric trauma units and maxillofacial surgeons.


Subject(s)
Mandibular Fractures , Adolescent , Adult , Aged , Child , Humans , Mandibular Fractures/diagnostic imaging , Mandibular Fractures/epidemiology , Retrospective Studies , Young Adult
5.
J Stomatol Oral Maxillofac Surg ; 121(4): 330-338, 2020 Sep.
Article in English | MEDLINE | ID: mdl-31533064

ABSTRACT

INTRODUCTION: The progressive aging of European population seems to determine a change in the epidemiology, incidence and etiology of maxillofacial fractures with an increase in the frequency of old patients sustaining craniofacial trauma. The objective of the present study was to assess the demographic variables, causes, and patterns of facial fractures in elderly population (with 70 years or more). MATERIALS AND METHODS: The data from all geriatric patients (70 years or more) with facial fractures between January 1, 2013, and December 31, 2017, were collected. The following data were recorded for each patient: gender, age, voluptuary habits, comorbidities, etiology, site of facial fractures, synchronous body injuries, Facial Injury Severity Score (FISS). RESULTS: A total of 1334 patients (599 male and 735 female patients) were included in the study. Mean age was 79.3 years, and 66% of patients reported one or more comorbidities. The most frequent cause of injury was fall and zygomatic fractures were the most frequently observed injuries. Falls were associated with a low FISS value (P<.005). Concomitant injuries were observed in 27.3% of patients. Falls were associated with the absence of concomitant injuries. The ninth decade (P<.05) and a high FISS score (P<.005) were associated with concomitant body injuries too. CONCLUSIONS: This study confirms the role of falls in the epidemiology of facial trauma in the elderly, but also highlights the frequency of involvement of females, and the high frequency of zygomatic fractures.


Subject(s)
Maxillofacial Injuries , Skull Fractures , Zygomatic Fractures , Accidental Falls , Aged , Female , Humans , Injury Severity Score , Male , Maxillofacial Injuries/epidemiology , Maxillofacial Injuries/etiology , Skull Fractures/epidemiology , Skull Fractures/etiology
6.
Oral Maxillofac Surg ; 24(1): 11-17, 2020 Mar.
Article in English | MEDLINE | ID: mdl-31691048

ABSTRACT

PURPOSE: The aim of this study was to evaluate the long-term health-related quality of life (HRQoL) of head and neck cancer patients with microvascular surgery. Surgical treatment causes great changes in patient HRQoL. Studies focusing on long-term HRQoL after microvascular reconstruction for head and neck cancer patients are scarce. METHODS: We conducted a prospective study of 93 patients with head and neck cancer and microvascular reconstruction in Helsinki University Hospital Finland. HRQoL was measured using the 15D instrument at baseline and after a mean 4.9-years follow up. Results were compared with those of an age-standardized general population. RESULTS: Of the 93 patients, 61 (66%) were alive after follow-up; of these, 42 (69%) answered the follow-up questionnaire. The median time between surgery and HRQoL assessment was 4.9 years (range 3.7-7.8 years). The mean 15D score of all patients (n = 42) at the 4.9-years follow up was statistically significantly (p = 0.010) and clinically importantly lower than at baseline. The dimensions of "speech" and "usual activities" were significantly impaired at the end of follow up. There was a significant difference at the 4.9-years follow-up in the mean 15D score between patients and the general population (p = 0.014). After follow up, patients were significantly (p < 0.05) worse off on the dimensions of "speech," "eating," and "usual activities." CONCLUSIONS: Long-term HRQoL was significantly reduced in the whole patient cohort. Speech and usual activities were the most affected dimensions in head and neck cancer patients with microvascular reconstruction at the end of the 4.9-years follow up.


Subject(s)
Head and Neck Neoplasms , Quality of Life , Finland , Follow-Up Studies , Humans , Prospective Studies , Surveys and Questionnaires
7.
Oral Maxillofac Surg ; 23(1): 27-34, 2019 Mar.
Article in English | MEDLINE | ID: mdl-30747349

ABSTRACT

PURPOSE: The aim of this study was to investigate the relationship between intraorbital volume change caused by orbital fracture and globe malposition (GMP) in blow-out fracture patients undergoing surgery and to clarify the significance of different radiologically detected predictors associated with GMP. PATIENTS AND METHODS: A 6-month prospective follow-up study of unilateral isolated orbital fractures was designed and implemented. The main outcome variable was GMP (present or absent); the secondary outcome was orientation of GMP (horizontal or vertical). The primary predictor variable was postoperative orbital volume difference determined as the difference between the fractured and non-fractured orbit (measured in milliliter and analyzed in milliliter and percentages). The explanatory variables were gender, age, treatment delay from trauma to surgery, fracture site, horizontal depth of the fracture, fracture area, maximum vertical dislocation of the fracture, and preoperative volume difference. RESULTS: A total of 15 patients fulfilled the inclusion criteria and were followed for 6 months from a larger cohort. GMP was detected in 6/15 patients (40.0%). GMP was more often present in large (≥ 2.5 cm2) fractures (55.6%), in combined orbital fractures (50.0%), and in fractures with preoperative volume difference ≥ 2.5 ml (62.5%) regardless of the postoperative volume correction. Postoperatively, patients with and without GMP displayed overcorrection of orbital volume; 4.15% corresponded to 1.15 ml (with GMP) and 7.6% corresponded to 1.9 ml (without GMP). CONCLUSION: GMP was present in large and combined orbital fractures. Clinically detectable postoperative GMP occurred despite satisfactory orbital reconstruction and overcorrection. Mild GMP, however, is not significant for the patient.


Subject(s)
Orbital Fractures , Follow-Up Studies , Humans , Orbit , Prospective Studies , Tomography, X-Ray Computed
8.
Br J Oral Maxillofac Surg ; 56(9): 835-840, 2018 11.
Article in English | MEDLINE | ID: mdl-30337162

ABSTRACT

The aim of this retrospective study was to analyse the incidence of complications and loss of flaps after primary reconstructions for oral cancer in 191 patients at our hospital over the five years 2005-2010. The patients' clinical and personal details, characteristics of the tumours, types of microvascular flap, complications, and outcomes were recorded. The soft tissue flaps used most often were the fasciocutaneous radial forearm free flap (RFFF) (n=86, 45%) and the anterolateral thigh free flap (ALTFF) (n=48, 25%) while the most commonly used osseous flap was the deep circumflex iliac artery flap (DCIA) (n=25, 13%). There were postoperative complications that required intervention in a quarter of the patients, most often in the age group 41-50 years (p=0.018). Older age was not associated with the development of complications. The overall survival of all free flaps was 181/191 (95%), and the only significant individual predictor of loss of a flap was reconstruction with a DCIA (p=0.016), five of the 25 of which were lost. We conclude therefore that DCIA free flaps are associated with an increased risk of failure; the method of osseous reconstruction for maxillofacial reconstruction should be selected carefully; and carefully chosen older patients do not seem to be at increased risk of morbidity.


Subject(s)
Free Tissue Flaps/blood supply , Mouth Neoplasms/surgery , Plastic Surgery Procedures , Postoperative Complications/epidemiology , Adult , Aged , Aged, 80 and over , Female , Graft Rejection , Humans , Incidence , Male , Middle Aged , Retrospective Studies , Survival Rate , Treatment Outcome
9.
Br J Oral Maxillofac Surg ; 56(9): 810-813, 2018 11.
Article in English | MEDLINE | ID: mdl-30220610

ABSTRACT

Our aims were to document the occurrence of neurosensory disturbances of the infraorbital nerve six months after operation for an orbital blow-out fracture, and to find out whether dexamethasone facilitates neurosensory regeneration. Patients were randomly assigned to one of two groups: the study group was given a total of dexamethasone 30mg, whereas the control group were given neither glucocorticoid nor placebo. Each patient's infraorbital neurosensory state was recorded preoperatively, immediately postoperatively, and six months later. A total of 18 patients were included, eight of whom had neurosensory disturbances six months after the initial trauma that was not affected by dexamethasone. Six of the seven patients who had a delay of seven days or more between trauma and operation had significantly prolonged disturbance at the 180-day clinical follow up compared with those in whom it was less than seven days (p=0.005). Other possible predictors made no significant difference. Although dexamethasone did not facilitate sensory recovery, its benefits in the management of pain and reduction of swelling may justify its use in the management of facial trauma in selected patients.


Subject(s)
Dexamethasone/therapeutic use , Glucocorticoids/therapeutic use , Orbit/innervation , Orbital Fractures/surgery , Postoperative Complications/prevention & control , Somatosensory Disorders/prevention & control , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Prospective Studies , Recovery of Function , Single-Blind Method , Treatment Outcome
10.
Br J Oral Maxillofac Surg ; 56(7): 573-577, 2018 09.
Article in English | MEDLINE | ID: mdl-29970263

ABSTRACT

The aim of this prospective follow-up study was to clarify the incidence and characteristics of dysfunction of the temporomandibular joint (TMJ) in patients treated surgically for fractures of the zygomatic complex. Patients were evaluated on presentation and six months after injury to assess the function of the masticatory system using the Helkimo index, which incorporates two complementary subindices: the subjective symptomatic (anamnestic) index (Ai) and the objective clinical dysfunction index (Di). Forty-five patients (12 women and 33 men, mean (range) age 44 (21-83)years) completed the study. Six patients developed subjective symptoms of dysfunction of the TMJ during follow-up, in four of whom they were severe. Clinical findings were noted in 38 patients but without significant association with subjective symptoms. Dysfunction of the TMJ is common six months after surgical treatment of a fracture of the zygomatic complex, and patients with such fractures should be evaluated for temporomandibular dysfunction during follow-up and referred for treatment when necessary.


Subject(s)
Postoperative Complications/epidemiology , Temporomandibular Joint Disorders/epidemiology , Zygomatic Fractures/surgery , Adult , Aged , Aged, 80 and over , Female , Follow-Up Studies , Humans , Male , Middle Aged , Prospective Studies , Risk Factors , Treatment Outcome
12.
Med Oral Patol Oral Cir Bucal ; 22(5): e636-e642, 2017 Sep 01.
Article in English | MEDLINE | ID: mdl-28809377

ABSTRACT

BACKGROUND: The objective was to evaluate health-related quality of life (HRQoL) before and after surgical treatment of zygomatic complex fracture and assess patients' perceptions of the aesthetic and functional outcomes of surgery. MATERIAL AND METHODS: A prospective study of 79 adult patients before and after surgery for zygomatic complex fracture was conducted. HRQoL was measured using the generic 15-dimensional (15D) instrument, and patient satisfaction was assessed by an additional questionnaire. RESULTS: The mean preoperative 15D score for patients was lower than for general population that was matched for age and gender (p=0.011). The mean 15D score was lowest on the first postoperative day (p<0.001) when patients were worse off for 6 of the 15 dimensions of the HRQoL instrument and better off for three dimensions. However, patients achieved, and even exceeded, the mean 15D score of the general population during the first month following surgery. Infraorbital sensory loss at the end of the six-month follow-up appeared to be the single most important factor that plagued the patients. CONCLUSIONS: HRQoL is significantly reduced after trauma but improves a few weeks after surgery. Infraorbital nerve sensory loss is a notable long-term factor that affects patients after zygomatic complex fracture.


Subject(s)
Quality of Life , Zygomatic Fractures/surgery , Adult , Female , Humans , Male , Prospective Studies , Self Report
13.
Int J Oral Maxillofac Surg ; 46(10): 1267-1270, 2017 Oct.
Article in English | MEDLINE | ID: mdl-28551283

ABSTRACT

This study aimed to establish the incidence of postoperative nausea and vomiting (PONV) in facial fracture patients. The specific aim was to investigate the effect of perioperative dexamethasone on PONV. A total of 119 adult patients with facial fractures were analysed in this prospective study. Patients were randomized to receive perioperatively either a total dose of 30mg of dexamethasone i.v. and i.m., or no glucocorticoid (control). PONV was evaluated every 6hours during the first postoperative 24hours and when pain medications were given. PONV occurred in 20 out of 119 patients (16.8%). The only significant (P=0.016) association with PONV was postoperative administration of opioids. Slightly more cases of PONV occurred for patients who had not received dexamethasone (20%) compared to those who had (13.6%). PONV was also non-significantly more common in patients ≥40 years (21.3%) than in patients < 40 years (12.1%), after orbital floor reconstruction (28.0%) compared with mandibular (11.6%) and zygomatic (15.6%) fractures surgeries, and also after anaesthesia lasting >97minutes (21.7%) compared with a shorter duration (11.3%). Alternative medications should be used for prevention of post-surgery nausea and vomiting in facial fracture patients.


Subject(s)
Antiemetics/therapeutic use , Dexamethasone/therapeutic use , Facial Injuries/surgery , Fracture Fixation, Internal/methods , Postoperative Nausea and Vomiting/prevention & control , Skull Fractures/surgery , Adolescent , Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Prospective Studies , Treatment Outcome
14.
Med Oral Patol Oral Cir Bucal ; 21(5): e614-20, 2016 Sep 01.
Article in English | MEDLINE | ID: mdl-27475690

ABSTRACT

UNLABELLED: Backround: The aim of this study was to assess changes in bone volume after block bone augmentation and placement of dental implants and further evaluate the aesthetic outcome of the treatment. MATERIAL AND METHODS: 9 patients with atrophied anterior maxilla were included in this study. They received total of 21 implants. Dimensions of the alveolar ridge were measured from cone-beam computed tomography x-rays. The bone level at the implant sites was analysed from intraoral x-rays and the aesthetic outcome was assessed from clinical photographs using a pink aesthetic score (PES) scaling. RESULTS: The mean gained horizontal bone width at the marginal crest and 5 mm apically was accordingly 2.7mm and 5.0 mm. The mean PES rating was 9.8/14. The survival rate of. CONCLUSIONS: Reconstruction of the atrophied anterior maxilla with bone blocks and dental implants is a safe procedure with high survival rate and acceptable aesthetic outcome.


Subject(s)
Alveolar Ridge Augmentation , Bone Transplantation , Dental Implants , Dental Implantation, Endosseous , Esthetics , Follow-Up Studies , Humans , Ilium , Maxilla , Treatment Outcome
15.
Int J Oral Maxillofac Surg ; 39(8): 774-8, 2010 Aug.
Article in English | MEDLINE | ID: mdl-20435438

ABSTRACT

The aim of this retrospective study was to clarify the occurrence and types of dental injuries in 389 patients who had been diagnosed with facial fractures, and to analyze whether the occurrence of dental injury correlates to gender, age, trauma mechanism and type of facial fracture. Dental injuries were observed in 62 patients (16%). The most common type of injury was a crown fracture (48%). Dental injuries were multiple in most patients (63%). Almost half (48%) of all injured teeth were severely injured. Most injured teeth (61%) were in the maxilla. The incisor region was the most prevalent site in both the mandible (45%) and the maxilla (56%). The occurrence of dental injury correlated significantly with trauma mechanism and fracture type: motor vehicle accidents and mandibular fracture were significant predictors for dental trauma. The notable rate of dental injury observed in the present study emphasizes the importance of a thorough examination of the oral cavity in all patients who have sustained facial fracture. Referral to a dental practice for further treatment and follow up as soon as possible after discharge from hospital is fundamental.


Subject(s)
Facial Bones/injuries , Fractures, Bone/epidemiology , Maxillofacial Injuries/epidemiology , Tooth Fractures/epidemiology , Tooth Injuries/epidemiology , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Child , Comorbidity , Female , Finland/epidemiology , Humans , Male , Middle Aged , Sex Distribution , Young Adult
16.
Int J Oral Maxillofac Surg ; 39(5): 430-5, 2010 May.
Article in English | MEDLINE | ID: mdl-20181459

ABSTRACT

Removal of miniplates is a controversial topic in oral and maxillofacial surgery. Originally, miniplates were designed to be removed on completion of bone healing. The introduction of low profile titanium miniplates has led to the routine removal of miniplates becoming comparatively rare in many parts of the world. Few studies have investigated the reasons for non-routine removal of miniplates and the factors that affect osteosynthesis after osteotomy in large numbers of patients. The aim of the present study was to investigate complications related to osteosynthesis after bilateral sagittal split osteotomy (BSSO) in a large number (n=153) of patients. In addition to the rates of removal, emphasis was placed on investigating the reasons and risk factors associated with symptomatic miniplate removal. The rate of plate removal per patient was 18.6%, the corresponding rate per plate being 18.2%. Reasons for plate removal included plate-related complications in 16 patients and subjective discomfort in 13 patients. Half of the plates were removed during the first postoperative year. Smoking was the only significant predictor for plate removal. Patients undergoing orthognathic surgery should be screened with regard to smoking and encouraged and assisted to cease smoking, at least perioperatively.


Subject(s)
Bone Plates/adverse effects , Device Removal , Jaw Fixation Techniques/instrumentation , Mandible/surgery , Orthognathic Surgical Procedures/instrumentation , Smoking/adverse effects , Adolescent , Adult , Bone Plates/psychology , Chi-Square Distribution , Equipment Failure , Female , Humans , Logistic Models , Male , Middle Aged , Osteotomy/instrumentation , Retrospective Studies , Risk Factors , Surgical Wound Infection/etiology , Surgical Wound Infection/surgery , Titanium , Young Adult
18.
Pflugers Arch ; 443(5-6): 858-65, 2002 Mar.
Article in English | MEDLINE | ID: mdl-11889586

ABSTRACT

To determine whether prenatal hypoxia increases the risk of developing cardiovascular disorders as an adult and, if so, the identity of the cell mechanisms involved in such dysfunction, we evaluated the sympathoadrenal system and central areas related to cardiovascular events during development and the cardiovascular parameters in adults. Pregnant rats were exposed to hypoxia (10% oxygen) from embryonic day (E) 5 to E20 and the offspring studied at 1, 3, 9 and 12 weeks of age for neurochemistry and at 12 weeks of age for cardiovascular analysis. In the 1-, 3- and 9-week-old offspring, the levels and utilization of catecholamines were reduced in sympathetic ganglia, in target organs, in adrenals and in the rostral part of the A2 cell group in the nucleus tractus solitarius, but were increased in the locus coeruleus. In the 12-week-old adult offspring, the lowered autonomic nervous activity was restricted to cardiac-related structures, i.e. the stellate ganglion, heart and adrenals. In adult rats, prenatal hypoxia did not affect the cardiac parameters under resting conditions but increased blood pressure and the variability of blood pressure and heart rate under stress conditions. The altered metabolic activity of the sympathoadrenal system and related central areas during development and at adulthood for most structures might be part of the potential mechanisms contributing to cardiovascular disorders in adults.


Subject(s)
Cardiovascular System/embryology , Hypoxia/physiopathology , Stellate Ganglion/embryology , Adrenal Glands/metabolism , Animals , Blood Pressure , Cardiovascular System/metabolism , Female , Heart Rate , Locus Coeruleus/embryology , Locus Coeruleus/metabolism , Myocardium/metabolism , Norepinephrine/metabolism , Organ Size , Oxygen/pharmacology , Pregnancy , Prenatal Exposure Delayed Effects , Rats , Rats, Sprague-Dawley , Stellate Ganglion/metabolism , Stress, Physiological/physiopathology
19.
J Oral Maxillofac Surg ; 59(7): 768-73; discussion 773-4, 2001 Jul.
Article in English | MEDLINE | ID: mdl-11429737

ABSTRACT

PURPOSE: The purpose of this study was to investigate the long-term clinical and radiologic outcome of nonsurgically treated, dislocated condylar fractures sustained during childhood. PATIENTS AND METHODS: Dislocated condylar process fractures were diagnosed in 34 children aged 15 years or younger from 1980 to 1991. Of these, 26 had been treated nonsurgically and were asked to participate in a follow-up examination. Eighteen patients, representing 69% of the total sample, took part in the study. All patients underwent a clinical investigation with special emphasis on temporomandibular joint (TMJ) function. The patients also underwent a radiologic investigation, focusing on fracture remodeling and symmetry of the mandible. RESULTS: After a follow-up period ranging from 4.8 to 16.4 years (mean, 8.6 years), 56% had some subjective symptoms, and 72% had some objective signs of TMJ dysfunction. In general, however, the symptoms and signs of dysfunction were very slight. No correlation was observed between the method of nonsurgical treatment and the clinical results. Radiologic investigation showed incomplete remodeling (76.5%) and asymmetry of the mandible (64.7%) in most patients. The asymmetry was slight, however, and could not be observed clinically. CONCLUSIONS: Conservative treatment of dislocated condylar process fractures in children results in satisfactory long-term outcome of jaw function despite a high frequency of radiologically noted aberrations. Soft diet with immediate mobilization seems to be the treatment of choice.


Subject(s)
Joint Dislocations/physiopathology , Mandibular Condyle/injuries , Mandibular Fractures/therapy , Adolescent , Bone Remodeling/physiology , Child , Child, Preschool , Diet , Female , Follow-Up Studies , Fracture Healing , Humans , Jaw Fixation Techniques , Joint Dislocations/diagnostic imaging , Joint Dislocations/therapy , Longitudinal Studies , Male , Mandible/diagnostic imaging , Mandibular Condyle/diagnostic imaging , Mandibular Condyle/physiopathology , Mandibular Fractures/diagnostic imaging , Mandibular Fractures/physiopathology , Radiography , Range of Motion, Articular/physiology , Statistics as Topic , Temporomandibular Joint/diagnostic imaging , Temporomandibular Joint/physiopathology , Temporomandibular Joint Disorders/etiology , Temporomandibular Joint Disorders/physiopathology , Treatment Outcome
20.
Article in English | MEDLINE | ID: mdl-9868735

ABSTRACT

OBJECTIVE: The purpose of this investigation was to study the radiologic outcomes of pediatric condylar fractures. STUDY DESIGN: Radiographs of 37 patients with 45 condylar fractures that had been diagnosed at the Department of Oral and Maxillofacial Surgery, Helsinki University Central Hospital were retrospectively reviewed. The frequency and characteristics of incomplete remodeling at an average of 4.1 years after the injury were studied. The influence of age and fracture type on remodeling were considered. RESULTS: Incomplete remodeling was observed after 56% of the fractures. The most frequent signs of incomplete remodeling were alteration in the configuration of the surface of the condylar head and deformation of the condylar neck. Incomplete remodeling was frequently (83%) related to fracture dislocation. For this fracture type the radiologic prognosis seems poor in all age groups. A difference in ramus height between the 2 sides was observed in 52% of the fractures, particularly frequently (80%) after fracture dislocation. CONCLUSIONS: Radiologic aberrations are frequent after pediatric condylar fractures. Dislocated fractures, in particular, need special attention and long-lasting clinical follow-up.


Subject(s)
Fractures, Malunited/diagnostic imaging , Mandibular Condyle/injuries , Mandibular Fractures/physiopathology , Temporomandibular Joint/diagnostic imaging , Adolescent , Age Factors , Bone Remodeling , Child , Child, Preschool , Female , Follow-Up Studies , Fractures, Malunited/pathology , Humans , Joint Dislocations/diagnostic imaging , Joint Dislocations/etiology , Male , Mandibular Condyle/diagnostic imaging , Mandibular Condyle/pathology , Mandibular Fractures/complications , Mandibular Fractures/diagnostic imaging , Mandibular Fractures/pathology , Radiography , Retrospective Studies , Temporomandibular Joint/pathology
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