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Internist (Berl) ; 62(5): 549-554, 2021 May.
Article in German | MEDLINE | ID: mdl-33326044

ABSTRACT

A 61-year-old female patient presented to the emergency room with nausea. Laboratory findings revealed metabolic acidosis, which had to be associated with a sodium-glucose co-transporter­2 (SGLT2) inhibitor. Due to increasing prescription rates of SGLT2 inhibitors for diabetes mellitus, congestive heart failure or chronic renal insufficiency, a growing numbers of cases of SGLT2 inhibitor-associated ketoacidosis should be expected. Calculating the anion gap can provide orientation in the case of acidosis of unknown origin. Presumably, a relevant proportion of such cases of ketoacidosis is currently being overlooked or its diagnosis delayed.


Subject(s)
Diabetes Mellitus, Type 2 , Diabetic Ketoacidosis , Ketosis , Sodium-Glucose Transporter 2 Inhibitors , Diabetes Mellitus, Type 2/diagnosis , Diabetes Mellitus, Type 2/drug therapy , Diabetic Ketoacidosis/chemically induced , Diabetic Ketoacidosis/diagnosis , Female , Humans , Hypoglycemic Agents , Ketosis/chemically induced , Ketosis/diagnosis , Middle Aged , Nausea
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