ABSTRACT
Third monomer dimethyl isophthalate-5-sodium sulfonate (SIPM) is an additive widely used to modify polyester chips. During the manufacture of SIPM, large amounts of waste third-monomer pressure filter liquid are produced. As the liquid contains lots of toxic organics and highly concentrated Na2SO4, it will cause serious environmental pollution if discharged directly. In this study, highly functionalized activated carbon (AC) was prepared by directly carbonizing the dried waste liquid under ambient pressure. Structural and adsorption properties of the prepared AC were analyzed and evaluated by X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared (FT-IR) spectroscopy, X-ray photoelectron spectroscopy (XPS), N2 adsorption-desorption analysis and methylene blue (MB) as the adsorbate, respectively. Results showed that the adsorption capacity of the prepared AC to MB reached the highest when carbonization was conducted at 400 °C. XRD analysis showed that the AC has a disordered graphite-like crystal structure. FT-IR and XPS analyses showed that there were plenty of carboxyl and sulfonic functional groups in the AC. The adsorption follows the pseudo-second-order kinetic model and the isotherm process is consistent with the Langmuir model. The adsorption capacity increased with increasing solution pH and dropped when the solution pH exceeded 12. Increasing solution temperature favors the adsorption, where the maximum value can reach as high as 2816.4 mg g-1 at 45 °C, more than double the values reported to date. The adsorption of MB on the AC is mainly controlled by the electrostatic interaction between MB and the anionic form of carboxyl and sulfonic groups.
ABSTRACT
Scedosporium and Lomentospora species are the second most frequent colonizing, allergenic, or invasive fungal pathogens in patients with cystic fibrosis, and are responsible for infections varying from cutaneous and subcutaneous tissue infections caused by traumatic inoculation to severe systemic diseases in immunocompromised patients. The clinical relevance of fungal airway colonization for individual patients harboring Scedosporium and Lomentospora species is still an underestimated issue. The high resistance of Scedosporium and Lomentospora species to antifungal drugs has highlighted the need for alternative treatment modalities, and antimicrobial photodynamic therapy may be one such alternative. In this study, methylene blue was applied as a photosensitizing agent to 6 type strains of Scedosporium and Lomentospora species, and we irradiated the strains using a light-emitting diode (635 ± 10 nm, 12 J/cm2). We evaluated the effects of photodynamic therapy on strain growth and on the in vitro susceptibility of the strains to itraconazole, voriconazole, posaconazole, and amphotericin B. A colony-forming unit reduction of up to 5.2 log10 was achieved. Minimal inhibitory concentration ranges also decreased significantly with photoinactivation. Photodynamic therapy improved both the inactivation rates and the antifungal susceptibility profile of all fungal isolates tested.
