1.
RSC Adv
; 9(52): 30570-30574, 2019 Sep 23.
Article
in English
| MEDLINE
| ID: mdl-35530231
ABSTRACT
An efficient method for the synthesis of N-thiomethyl benzimidazoles from o-phenylenediamines, thiophenols, and aldehydes via C-N/C-S bond formation under metal-free conditions is described. A broad range of functional groups attached to the substrates were well tolerated in this reaction system. Stable and low-toxicity paraformaldehyde was used as the carbon source.