1.
Biochimie
; 71(11-12): 1157-61, 1989.
Article
in English
| MEDLINE
| ID: mdl-2517476
ABSTRACT
We have previously described in rat liver two protein kinases tightly bound to DNA, one is serine-specific, the other arginine-specific. In this work we show that both enzymes are present in various rat tissues and in liver from various species. Both kinase specific activities are strongly decreased in methyl-DBA-induced hepatomas and in HTC cells but not in regenerating liver after hepatectomy. This decrease is then not related to cell proliferation.