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Ophthalmic Surg Lasers Imaging Retina ; 54(3): 183-187, 2023 03.
Article in English | MEDLINE | ID: mdl-36944065

ABSTRACT

The use of checkpoint inhibitors has been associated with multiple ocular and orbital complications including Vogt-Koyanagi-Harada disease. In the current case, a 55-year-old man presented with visual changes 3 months following discontinuation of nivolumab for metastatic renal cell carcinoma. This is the second report of delayed presentation following discontinuation of a checkpoint inhibitor and the only case not associated with an alternative targeted therapy at the time of presentation. This article highlights a unique presentation of delayed checkpoint inhibitor-associated Vogt-Koyanagi-Harada and summarizes the reported cases. [Ophthalmic Surg Lasers Imaging Retina 2023;54(3):183-187.].


Subject(s)
Immune Checkpoint Inhibitors , Nivolumab , Uveomeningoencephalitic Syndrome , Humans , Male , Middle Aged , Carcinoma, Renal Cell/drug therapy , Carcinoma, Renal Cell/complications , Eye , Kidney Neoplasms/drug therapy , Kidney Neoplasms/complications , Nivolumab/adverse effects , Uveomeningoencephalitic Syndrome/chemically induced , Uveomeningoencephalitic Syndrome/diagnosis , Uveomeningoencephalitic Syndrome/drug therapy , Immune Checkpoint Inhibitors/adverse effects
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