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Ophthalmologica ; 220(3): 190-3, 2006.
Article in English | MEDLINE | ID: mdl-16679795

ABSTRACT

PURPOSE: To determine a novel vital dye (patent blue; Blueron) for vitreoretinal surgery in a prospective consecutive case series. METHODS: Five patients with either idiopathic epiretinal membrane (ERM; n = 2), proliferative vitreoretinopathy (n = 2), or a macular hole (n = 1) underwent a three-port pars plana vitrectomy. Patent blue assisted staining of the retinal surface followed by a consecutive peeling of the ERM (n = 4) or of the internal limiting membrane (ILM; n = 1) was performed. The main outcome measures were quality of intraoperative visualization of preretinal structures and postoperative visual acuity. RESULTS: The dye induced a moderate staining (++) of the ERM and a mild staining (+) of the ILM. Complete ERM and ILM removal was successfully achieved in all cases. A mean visual improvement of three Snellen lines was observed 6 months postoperatively. No visual field defects or visible retinal pigment epithelial changes were present 6 months postoperatively. CONCLUSION: Patent blue, a novel dye for intraocular applications, may be added as an alternative dye in chromovitrectomy.


Subject(s)
Coloring Agents , Epiretinal Membrane/surgery , Retinal Perforations/surgery , Rosaniline Dyes , Vitrectomy/methods , Vitreoretinopathy, Proliferative/surgery , Absorption , Coloring Agents/pharmacokinetics , Epiretinal Membrane/metabolism , Epiretinal Membrane/pathology , Follow-Up Studies , Humans , Prospective Studies , Retinal Perforations/metabolism , Retinal Perforations/pathology , Rosaniline Dyes/pharmacokinetics , Spectrum Analysis , Vitreoretinopathy, Proliferative/metabolism , Vitreoretinopathy, Proliferative/pathology
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