[Acceptance of telemedicine for acute stroke care. The German project TEMPiS]. / Akzeptanz der Telemedizin in der akuten Schlaganfallversorgung. Das bayerische Projekt TEMPiS.

BACKGROUND: Telemedicine is increasingly used for acute stroke care, making neurological expertise available in nonspecialized hospitals. There are few data about telemedicine's acceptance by either medical staff or patients at treating hospitals. METHODS: Telemedicine's acceptance was evaluated in the Telemedical Project for Integrative Stroke Care (TEMPIS), a network of two stroke centers and 12 community hospitals in the German state of Bavaria; the grading of teleconsultation regarding video and audio quality, time consumption, and medical relevance was assessed in two periods, 2004 and 2007. Overall satisfaction with in-hospital treatment was compared between patients in telemedically-linked hospitals with specialized stroke care and patients treated in conventional community hospitals. With regard to sufficient follow-up rates, ratings were restricted to patients living at home without severe disability at 3 months after stroke. A second evaluation analyzed how the parameter "Telemedical assessment of patient" (36% of patients in TEMPIS hospitals) affected overall satisfaction. RESULTS: Respectively, 140 and 127 uses of telemedicine were assessed in the two evaluation periods. Video quality, time consumption, and medical relevance were graded "excellent" by over 50% in both periods. Audio quality was rated "excellent" by only 22% in the first period but 69% in the second. Excellent overall satisfaction was expressed significantly more frequently by patients at TEMPIS hospitals (total number 1044) than by those at control hospitals (total number 484; 56% vs 47% respectively, P<0.01). Patient consultation via telemedicine per se did not correlate with modified grading. CONCLUSIONS: Acceptance of telemedicine in acute stroke care was high and stable over a long period. This study suggests improved overall satisfaction with treatment in hospitals offering specialized care and linked via telemedicine. Clinical assessment via telemedicine had no major effect on satisfaction.

Percutaneous ultrasound-guided radiofrequency ablation (RFA) using saline-perfused (wet) needle electrodes for the treatment of hepatocellular carcinoma--long term experience.

PURPOSE: For many reasons, resection of hepatocellular cancer (HCC) is not feasible in most cases. Radiofrequency (RFA) ablation has proven to be an effective minimally invasive alternative. It has been shown in ex vivo and animal trials that needle applicators perfused with isotonic saline solution could be an effective approach to enlarging the coagulation zone. However, long term survival data for the treatment of HCC are not yet available. MATERIALS AND METHODS: 37 patients with a total of 64 histologically proven HCC with a maximum of 3 tumors of up to 6 cm and a contraindication to partial liver resection or orthotopic liver transplantation were treated with the Integra HiTT106 using wet monopolar single, wet bipolar double or wet triple needle electrodes. The mean HCC size was 37.7 mm (range 15 to 60 mm). Follow-up examinations were performed 2 days and 1, 3, 6, 9 months after RFA and every 6 months thereafter. The survival rate was calculated from the time of the first RFA session. RESULTS: 1, 2 and 5-year survival was 24/32 (75%), 14/31 (45%) and 3/21 (14%) overall; 18/19 (95%), 12/18 (67%) and 3/10 (30%) for HCC Child A; and 6/13 (46%), 2/13 (15%) and 0/11 (0%), for HCC Child B. Complete remission was achieved in 86.5 % of the patients (total: 32 out of 37, multi-needle 18 / 21, single needle 14 / 16). Distant recurrence occurred overall in 20 out of 37 patients (54%), including 9 of 21 treated with multiple needles (43% of patients) and 11 of the 16 patients treated with a single electrode (69%). The overall complication rate was 10.8%. Local recurrence was found for tumors measuring 3 cm-5 cm (n=28) in 7 out of 13 cases after single electrode RFA and in 1 out of 15 after multiple electrode treatment (significant, p=0.009). No significant difference between the single and multi-needle group was found for tumors >5 cm and <3 cm. CONCLUSION: RFA using multiple wet electrodes shows promise as an effective method for treating inoperable HCC especially in cases with well-preserved liver function. Multiple electrodes seem to be superior to single electrodes with respect to the local recurrence rate for tumors between 3 and 5 cm.