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3.
Radiats Biol Radioecol ; 39(4): 451-4, 1999.
Article in Russian | MEDLINE | ID: mdl-10542876

ABSTRACT

DNA-protein cross-links in white blood cells of Apodemus agrarius and Clethrionomys glareolus dwelling in the territory of the guarded zone of the radioactive waste storage in Sergievo Posad (area with gamma-background 50-400 microR/h) have been determined. As a control the animals from sanitary protected area of Sergievo Posadsky department (gamma-background on the soil surface is 8-10 microR/h) was used. It was found that the doses received by Apodemus agrarius and Clethrionomys glareolus, resulted in increasing of the DNA-protein cross-link level in the Apodemus agrarius white blood cells by a factor of 1.8, and in Clethrionomys glareolus by a factor of 1.4, in comparison with control. The increase of DNA-protein cross-link number reliably correlates with the beta-emitting nuclide content in animal bodies. The changes in the number white of cells and in the white blood composition were not observed.


Subject(s)
Arvicolinae/blood , Blood Proteins/metabolism , DNA/blood , Leukocytes/metabolism , Muridae/blood , Radioactive Waste , Animals , Blood Protein Electrophoresis , Blood Proteins/analysis , DNA/analysis , Data Interpretation, Statistical , Electrophoresis, Agar Gel , Leukocytes/chemistry
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