ABSTRACT
Our study evaluates the correlation between benign and malignant breast masses contrast enhancement, on the one hand, and the type of the vascular net and histological prognosis, on the other. We reviewed the preoperative images of 298 breast masses (benign--95 (32%), malignant--203 (68%)) after dynamic contrast enhancement as well as on the basis of pathomorphological data. Due to use of high-concentration paramagnetic contrast agents in ultra-fast sequences, benign and malignant tumors could be differentiated. The quantitative data on both intensive contrast and ring-shaped enhancement corresponded to the low capillary density in the center of carcinoma which correlated with poor prognosis.
Subject(s)
Breast Neoplasms/diagnosis , Breast/blood supply , Magnetic Resonance Imaging , Mammography/methods , Microcirculation , Adult , Breast Diseases/diagnosis , Breast Neoplasms/blood supply , Breast Neoplasms/pathology , Capillaries , Contrast Media , Female , Humans , Magnetic Resonance Angiography/methods , Magnetic Resonance Imaging/methods , Predictive Value of Tests , PrognosisABSTRACT
Potential of contrast-enhanced MR imaging (MRI) in diagnosis of breast tumors was studied in 112 patients aged 18-64 (76 suspects and 36--after combined treatment). The method proved highly-effective and specific--92 and 81%, respectively. The best timing was 3 months after surgery and 8 months after irradiation. No significant advantage of either one- or polymolar contrast agents was observed. MRI is highly efficient in diagnosing hypervascular formations, tumor grading and making prognosis. It is a method of choice in evaluating neoadjuvant polychemotherapy findings and combined treatment monitoring.
