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1.
BMJ Case Rep ; 15(4)2022 Apr 15.
Article in English | MEDLINE | ID: mdl-35428666

ABSTRACT

A woman in her late 40s who works as a veterinary technician represented to the emergency department with increasing headache, confusion, neck stiffness, subjective fevers and distorted hearing 2 days after diagnosis of viral infection at an outside emergency department.Diagnosis of Pasteurella multocida was made from blood cultures and lumbar puncture. Intravenous ceftriaxone was administered for 21 days. By the time of resolution of acute meningitis, she had become completely deaf bilaterally. MRI revealed faint early ossification/possible labyrinthitis ossificans of the basal cochlea, which was confirmed on surgical exploration during the placement of cochlear implants bilaterally 42 days later. We discuss how the atypical features of this infection lead to diagnostic delay and high morbidity, the unique imaging/surgical findings resulting from the infection, and the clinical utility of early and bilateral cochlear implantation in this and similar cases.


Subject(s)
Cochlear Implantation , Cochlear Implants , Deafness , Meningitis, Bacterial , Ossification, Heterotopic , Pasteurella multocida , Deafness/surgery , Delayed Diagnosis , Female , Humans , Meningitis, Bacterial/complications , Meningitis, Bacterial/diagnosis , Meningitis, Bacterial/drug therapy , Ossification, Heterotopic/surgery
2.
BMJ Case Rep ; 13(8)2020 Aug 18.
Article in English | MEDLINE | ID: mdl-32816933

ABSTRACT

A 79-year-old man with liver failure, hypertension and hyperlipidemia presented with a 1.5-month history of progressive nasal crusting and pain on the inside of the nose, advancing into a necrotic columella and philtrum. On rigid endoscopy, debris extended to middle and inferior turbinate to midway posteriorly. Initial culture swabs and CT were negative. The patient underwent endoscopic biopsy of the lesion, with histopathological findings revealing abundant acute inflammation and minute fragments of atypical squamous epithelium, favouring reactive atypia. Non-invasive fungal hyphae were identified. Bacterial cultures revealed Staphylococcus epidermidis, Corynebacterium accolens, Curvularia species and Pseudomonas putida A current literature search failed to find other published cases of P. putida nasal infections. P. putida is generally difficult to isolate on swab culture as the surrounding tissue is necrosed; this case highlights the importance of reconsidering bacterial infection and obtaining a tissue biopsy in the case of non-healing necrotic-appearing tissue with negative culture swab and CT without evidence of mass.


Subject(s)
Immunocompromised Host , Liver Failure, Acute/immunology , Necrosis/microbiology , Nose/microbiology , Pseudomonas Infections/diagnosis , Pseudomonas putida/isolation & purification , Aged , Anti-Bacterial Agents/therapeutic use , Diagnosis, Differential , Humans , Male , Nose/pathology , Pseudomonas Infections/complications , Pseudomonas Infections/drug therapy , Pseudomonas Infections/pathology
3.
BMJ Case Rep ; 12(3)2019 Mar 25.
Article in English | MEDLINE | ID: mdl-30914413

ABSTRACT

Thyroglossal duct cysts (TGDCs) are the most common congenital neck mass and often present in the paediatric population as a painless mass in the midline. A lateralised neck mass presenting for the first time in an adult may raise more concern for malignancy or a laryngocele. A 50-year-old man presented with an asymptomatic right level II neck mass adjacent to the thyroid cartilage. Preoperative CT revealed a cystic mass right of the midline with an intralaryngeal component. Intraoperatively, the lesion tracked towards the central hyoid bone; a Sistrunk procedure was performed. Postoperative pathology revealed a small foci of thyroid tissue within the mass. Careful consideration of the origin of this unusually presenting TGDC enabled appropriate operative management.


Subject(s)
Laryngocele/diagnosis , Thyroglossal Cyst/diagnosis , Diagnosis, Differential , Humans , Hyoid Bone/pathology , Male , Middle Aged , Neck/pathology
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