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Patol Fiziol Eksp Ter ; (4): 10-2, 1995.
Article in Russian | MEDLINE | ID: mdl-8700583

ABSTRACT

Experiments on mature male rats have shown that 3 and 6 months after removal of the brain thymus, the level of total lipids in all cell centrifugate fractions (homogenate, supramitochondrial and mitochondrial fractions), which was followed by the higher rate of lipid peroxidation and the lower activity of cellular compartments, the spectrum imbalance of lipid fractions with predominant increases in the levels of phospholipids and free cholesterol. It is suggested that these changes make a contribution to the dysfunction of brain structures and participate in regulatory processes in thymectomy.


Subject(s)
Brain/metabolism , Lipid Metabolism , Lipid Peroxidation/physiology , Thymus Hormones/deficiency , Animals , Female , Male , Rats
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