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1.
Psychiatry Res ; 270: 503-509, 2018 12.
Article in English | MEDLINE | ID: mdl-30347377

ABSTRACT

BACKGROUND: Patients' perception of psychiatric healthcare is a critical indicator in measuring service quality. The aim of the study was to determine patient's level of satisfaction with the quality of health care delivered at the inpatient departments, and to identify the service quality factors that were important to patients. METHOD: The Satisfaction with Psychiatry Care Questionnaire-22 was administered to 125 consecutive inpatients with schizophrenia or schizoaffective disorder in a stable condition. Sociodemographic and background variables, illness and symptom severity, insight, social anhedonia, self-esteem, perceived social support, and satisfaction with quality of life were collected. RESULTS: Although the participants generally expressed satisfaction with the inpatient services, they indicated that the weakest aspects of the service were in the domains of 'personal experience', 'information' and 'activity'. Women were significantly more dissatisfied than men with 'staff', 'care', and by general satisfaction. Multiple regression analysis revealed that satisfaction with hospital health care was associated with five indicators: insight, satisfaction with physical health, self-efficacy, family support, and social anhedonia. CONCLUSION: Personality related factors rather than psychopathological symptoms were associated with a satisfaction with care of admitted patients with severe mental illness. These factors could be targets for interventions aimed to improve treatment and hospital services.


Subject(s)
Inpatients/psychology , Patient Satisfaction , Psychotic Disorders/psychology , Schizophrenic Psychology , Adult , Anhedonia , Female , Humans , Male , Middle Aged , Personality , Quality of Life , Self Concept , Self Efficacy , Social Support , Surveys and Questionnaires
2.
Int Clin Psychopharmacol ; 28(2): 96-8, 2013 Mar.
Article in English | MEDLINE | ID: mdl-23211492

ABSTRACT

The current data suggest that up to 50% of patients with schizophrenia have obsessive-compulsive (OC) symptoms coexisting with psychosis and between 7.8 and 46% of schizophrenia patients also have full-blown obsessive-compulsive disorder (OCD). The aim of this study was to examine the efficacy of the most selective serotonin reuptake inhibitor escitalopram in the management of OCD in schizophrenia patients. The study was an open-label prospective trial of 12 weeks' duration in which escitalopram at a dose of up to 20 mg/day was added to the existing antipsychotic drug regimen in schizophrenia patients with OCD. Fifteen patients (10 men/five women) with the diagnosis of schizophrenia and OCD were recruited for the study (mean age: 39±14, range 21-61 years) and received escitalopram according to the study design. A significant improvement was observed in the total Yale Brown Obsessive-Compulsive Scale (Y-BOCS) scores and in the scores of both the Y-BOCS-Obsession and the Y-BOCS-Compulsion subscale at the end point. In addition, a significant improvement was observed in the total scores of the Positive and Negative Syndrome Scale and particularly in scores of anxiety, tension, depression, and preoccupation items. No adverse effects of escitalopram were reported by patients during the trial. In our prospective 12-week open-label study, escitalopram 20 mg/day was well tolerated and improved OC symptoms in schizophrenia patients. Our preliminary results are encouraging and a double-blind randomized study is required to confirm our results.


Subject(s)
Antipsychotic Agents/therapeutic use , Citalopram/therapeutic use , Obsessive-Compulsive Disorder/drug therapy , Schizophrenia/drug therapy , Selective Serotonin Reuptake Inhibitors/therapeutic use , Adult , Antipsychotic Agents/adverse effects , Anxiety/prevention & control , Citalopram/adverse effects , Compulsive Behavior/prevention & control , Diagnostic and Statistical Manual of Mental Disorders , Drug Therapy, Combination/adverse effects , Female , Humans , Male , Middle Aged , Obsessive Behavior/prevention & control , Obsessive-Compulsive Disorder/complications , Psychiatric Status Rating Scales , Schizophrenia/complications , Selective Serotonin Reuptake Inhibitors/adverse effects , Young Adult
4.
Depress Anxiety ; 25(11): E154-7, 2008.
Article in English | MEDLINE | ID: mdl-17994587

ABSTRACT

It has been suggested that an elevated serum or plasma homocysteine level may be a risk factor for neuropsychiatric conditions such as Alzheimer's disease, schizophrenia, and depression. Because depression is closely related to anxiety disorders, and because it has been suggested that stress may be associated with an elevated homocysteine level, we studied whether serum homocysteine levels are elevated in patients with posttraumatic stress disorder (PTSD). Total serum homocysteine levels in 28 male patients with PTSD were compared to those of 223 healthy controls. The effect of PTSD on the serum homocysteine level was significant (F=42.96, P<.0001). In a regression model for the PTSD patients, the duration of PTSD was found to predict serum homocysteine levels (t=2.228, P=.035). Our results suggest that elevated levels of homocysteine in male patients with PTSD may be related to pathophysiological aspects associated with the chronicity of this disorder.


Subject(s)
Homocysteine/blood , Stress Disorders, Post-Traumatic/blood , Stress Disorders, Post-Traumatic/physiopathology , Adult , Alzheimer Disease/blood , Alzheimer Disease/epidemiology , Alzheimer Disease/physiopathology , Chronic Disease , Depression/blood , Depression/epidemiology , Depression/physiopathology , Humans , Male , Middle Aged , Risk Factors , Schizophrenia/blood , Schizophrenia/epidemiology , Schizophrenia/physiopathology , Stress Disorders, Post-Traumatic/epidemiology , Young Adult
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