Advanced restorative management of focal microdontia: A brief review and case report.

Focal microdontia is a dental anomaly characterized by the presence of a single abnormally small anterior or posterior tooth. The objective of this article is to provide an updated review of the literature on the advanced restorative management of focal microdontia, and to document a clinical case where the reviewed advanced restorative approaches were applied to treat a young adult presenting with a non-syndromic asymmetrical focal microdontia.We conducted a preliminary examination of the existing literature on the advanced restorative management of focal microdontia. Additionally, we presented a minimally invasive approach to the treatment of an 18-year-old female patient with non-syndromic asymmetrical focal microdontia. The primary advantage of adhesive dentistry is that it can better preserve the structure of smaller teeth. A review of literature reveals a paucity of reports on localized microdontia in the maxillary anterior region of the mouth. However, novel minimally invasive restorative procedures satisfy patients' aesthetic and functional preferences. Well-executed additive diagnostic wax-ups and intraoral mock-ups can serve as a permanent restoration blueprint, providing predictable results for focal dental anomalies in the aesthetic zone. In conclusion, the use of minimally invasive dental approaches in young patients with focal microdontia can result in long-term satisfactory aesthetic outcomes.

Immediate implant placement with soft tissue grafting and an ultra-translucent zirconia crown. Replacement of a primary tooth in the esthetic zone

OBJECTIVES: The present case report describes the atraumatic extraction of a primary maxillary right canine followed by immediate implant placement with a customized zirconia abutment and monolithic ultra-translucent zirconia (5Y-PSZ) crown. CLINICAL CONSIDERATIONS: A 31-year-old patient presented to the clinic with the primary concern of mobility and gingival inflammation around the maxillary right canine. After clinical evaluation, the tooth was found to be a primary retained tooth that presented grade 3 mobility and gingival inflammation. Atraumatic tooth extraction was performed, followed by immediate implant placement of a screw-retained provisional restoration with the use of a surgical guide. The soft tissue was contoured until ideal architecture was obtained. The final restoration included a customized zirconia and titanium abutment and a characterized implant-supported monolithic 5Y-PSZ crown. CONCLUSIONS: Well-planned surgical and restorative procedures including atraumatic extraction, 3D implant planning for surgical guide fabrication, implant placement, and a customized zirconia abutment with a monolithic 5Y-PSZ crown can achieve high esthetic results in replacing a primary tooth in the esthetic zone.

Tooth-reduction 3D-printed guides for facilitating the provision of ultrathin laminate veneers.

Tooth-reduction guides offer a more controlled and conservative tooth preparation. Many types of tooth-reduction guides are available such as those with horizontal or vertical reduction grooves. A transparent cross-shaped tooth-reduction guide allows the clinician to make vertical and horizontal depth grooves to evaluate tooth reduction in all directions. The reference grooves on the guide enable the clinician to use a periodontal probe to measure the reduction accurately, and the transparent material provides a clear view of the entire tooth. Controlled tooth reduction offers a more conservative approach that is key for long-term bonded ceramic restorations. The multiaxial rigid transparent tooth-reduction guide could facilitate the provision of ultrathin handcrafted porcelain veneers to predictably fulfill patients' esthetic demands while preserving more tooth structure. The use of technically sound and artistically documented photographic evidence further underscores the effectiveness of this approach, particularly when intra-enamel preparations and adhesive luting under rubber dam isolation are employed. The present article describes a novel 3D-printed guide design that allows the clinician to perform the reduction grooves and evaluate the preparation in the horizontal and vertical directions within the same guide.

Differences in the absolute muscle strength and power of children and adolescents with overweight or obesity: a systematic review.

This study aimed to describe absolute muscle strength and power in children and adolescents with obesity, overweight and normal weight, and the assessment tests and tools used. We retrieved observational studies from MEDLINE (PubMed), TripDataBase, Epistemonikos, EBSCO essentials, NICE, SCOPUS, and LILACs up to February 2023. In addition, we recovered data from studies with at least three comparison groups (obesity, overweight, normal weight) and with a description of the absolute muscle strength and power and the assessment tests and instruments used. The methodologic quality of the studies was assessed with the Joanna Briggs checklist, and the review was carried out using the PRISMA 2020 methodology. Eleven studies with 13,451 participants from 6 to 18 years of age were once included, finding that the absolute muscle strength of their upper extremities was greater when they were overweight or obese; however, in the same groups, absolute muscle strength was lower when they carried their body weight. In addition, lower limb absolute muscle strength was significantly lower in obese participants than in normal weight, regardless of age and gender. The most used tools to measure the absolute muscle strength of the upper limbs were the grip dynamometers and push-up exercises. In contrast, different jump tests were used to measure the power of the lower limbs. There are great differences in muscle strength and power between overweight or obese children and adolescents and those with normal weight. Therefore, it is recommended to use validated tests, preferably that assess strength through the load of the patient's body weight, either of the upper or lower limbs, for greater evaluation objectivity that facilitates the management of these children and adolescents.

Combination of minimal- and non-preparation techniques with ceramic veneers for managing esthetic deficiencies.

Non-preparation (non-prep) ceramic veneers are a convenient and conservative treatment option, but controversy exists about their predictability. Concerns remain about possible overcontouring, poor-quality margins, and early esthetic failure. The present clinical report describes the combination of minimally invasive and non-prep ceramic laminate veneers in the esthetic zone with a 6-year follow-up to replace stained composite resin veneers on both maxillary central incisors. Composite resin veneers on the maxillary central incisors were replaced with ceramic veneers, and a non-prep ceramic veneer was placed on the maxillary right lateral incisor. A diagnostic additive wax-up was done, followed by a mock-up guide to conservatively prepare both maxillary central incisors. The three feldspathic porcelain veneer restorations were cemented under rubber dam isolation. The 6-year follow-up showed that stained composite resin veneers can successfully be replaced with minimally invasive and non-prep ceramic veneers to meet the patient's esthetic wishes. Overall, well-planned and well-executed restorative procedures combining minimal preparation and non-prep for ceramic laminate veneers can achieve esthetically pleasing outcomes and maximize tooth structure preservation in the maxillary anterior region.

An Innovative 3D Printed Tooth Reduction Guide for Precise Dental Ceramic Veneers.

Tooth reduction guides allow clinicians to obtain the ideal space required for ceramic restorations. This case report describes a novel design (CAD) for an additive computer-aided manufactured (a-CAM) tooth reduction guide with channels that permitted access for the preparation and evaluation of the reduction with the same guide. The guide features innovative vertical and horizontal channels that permit comprehensive access for preparation and evaluation of the reduction with a periodontal probe, ensuring uniform tooth reduction and avoiding overpreparation. This approach was successfully applied to a female patient with non-carious lesions and white spot lesions, resulting in minimally invasive tooth preparations and hand-crafted laminate veneer restorations that met the patient's aesthetic demands while preserving tooth structure. Compared to traditional silicone reduction guides, this novel design offers greater flexibility, enabling clinicians to evaluate tooth reduction in all directions and providing a more comprehensive assessment. Overall, this 3D printed tooth reduction guide represents a significant advancement in dental restoration technology, offering clinicians a useful tool for achieving optimal outcomes with minimal tooth reduction. Future work is warranted to compare tooth reductions and preparation time for this guide to other 3D printed guides.

Infección con SARS-CoV2, antes y después de la vacunación, en funcionarios de un hospital de mediana y alta complejidad / Sars-CoV2 infection, before and after vaccination, in health care workers of a medium and high complexity hospital

Introducción: La pandemia de COVID-19 evidenció la importancia de los trabajadores esen-ciales de la salud. Objetivo: Estimar la ocurrencia de la infección por el virus Sars_CoV2 en funcionarios de un hospital, antes y después de implementación del programa de vacunación institucional y la fracción preventiva atribuible a la vacunación. Material y métodos: Estudio de cohorte histórica, teniendo como punto de inicio la fecha del primer funcionario diagnosticado con la Covid19 en el Hospital. Alrededor de mil traba-jadores fueron examinados, durante el periodo de estudio comprendido entre junio de 2020 y octubre 2021. Se utilizó el estadístico de Kaplan-Meier, para comparar la velocidad de infección y la fracción preventiva atribuible al programa de vacunación. Resultados. Hubo diferencias estadísticamente significativas en la reducción de casos según tipo de trabajo, los trabajadores asistenciales experimentaron una reducción del 58,1%, de 124 a 52 y la diferencia en la mediana de la velocidad de infección, antes y después, Log Rank = 127,4 gl = 1 p = 0,000; los administrativos 51,7% de 29 a 14, mediana log Rank = 34,4 gl = 1 p = 0,000, y los operativos 45,5% de 11 a 6, mediana Log Rank = 13,5 gl = 1 p = 0,000. La fracción atribuible preventiva entre los asistenciales fue 47,5% (37,4­54,9); 85,2% (77,7­88,9) en administrativos y una reducción no significativa de 43,6% (-20,7, 63,2) en operativos. Conclusiones: Los trabajadores asistenciales tienen un riesgo alto de contraer la infección por Sars_CoV2. Fue una acertada decisión vacunar a todos los trabajadores del hospital, el impacto es demostrable.

Introduction: The COVID-19 pandemic highlighted the importance of essential health care workers.Objective: To estimate the occurrence of Sars_CoV2 virus infection in hospital staff before and after implementation of the institutional vaccination program and the preventive fraction attributable to vaccination. Material and methods: Historical cohort study, having as starting point the date of the first employee diagnosed with Covid19 in the Hospital. About one thousand workers were exa-mined, during the study period from June 2020 to October 2021. The Kaplan-Meier statistic was used to compare the infection, rate and the preventive fraction attributable to the vac-cination program. Results: There were statistically significant differences in the reduction of cases according to type of work, with the assistential workers experiencing a reduction of 58.1%, from 124 to 52 and the difference in median infection rate, before and after, Log Rank = 127.4 gl = 1 p = 0.000; the administrative 51.7% from 29 to 14, median Log Rank = 34.4 gl = 1 p = 0.000, and the operatives 45.5% from 11 to 6, median Log Rank = 13.5 gl = 1 p = 0.000. The preventive attributable fraction among assistants was 47.5% (37.4-54.9); 85.2% (77.7-88.9) in adminis-trative and a non-significant reduction of 43.6% (-20.7, 63.2) in operatives.Conclusions: Healthcare workers are at high risk of contracting Sars_CoV2 infection. It was a wise decision to vaccinate all hospital workers, the impact is demonstrable.

Diagnostic Mock-Up as a Surgical Reduction Guide for Crown Lengthening: Technique Description and Case Report.

Background and Objectives: The report describes a technique using a diagnostic mock-up as a crown-lengthening surgical guide to improve the gingival architecture. Materials and Methods: The patient's primary concern was improving her smile due to her "gummy smile" and short clinical crowns. After clinical evaluation, surgical crown lengthening accompanied by maxillary central full-coverage single-unit prostheses and lateral incisor veneers was recommended. The diagnostic mock-up was placed in the patient's maxillary anterior region and used as a soft tissue reduction guide for the gingivectomy. Once the planned gingival architecture was achieved, a flap was reflected to proceed with ostectomy in order to obtain an appropriate alveolar bone crest level using the overlay. After six months, all-ceramic crowns and porcelain veneers were provided as permanent restorations. Results: A diagnostic mock-up fabricated with a putty guide directly from the diagnostic wax-up can be an adequate surgical guide for crown-lengthening procedures. The diagnostic wax-up was used to fabricate the diagnostic mock-up. These results suggested that it can be used as a crown-lengthening surgical guide to modify the gingival architecture. Several advantages of the overlay used in the aesthetic complex case include: (1) providing a preview of potential restorative outcomes, (2) allowing for the appropriate positioning of gingival margins and the desired alveolar bone crest level for the crown-lengthening procedure, and (3) serving as a provisional restoration after surgery. Conclusions: The use of a diagnostic mock-up, which was based on a diagnostic wax-up, as the surgical guide resulted in successful crown lengthening and provisional restorations. Thus, a diagnostic overlay can be a viable option as a surgical guide for crown lengthening.

Additive Wax-Up and Diagnostic Mockup As Driving Tools for Minimally Invasive Veneer Preparations.

This report describes the importance of and outlines steps for additive wax-up and diagnostic mockup for anterior teeth as diagnostic and driving tools for non-prep and minimally invasive veneer preparations. A 35-year-old male presented to the clinic with the chief complaint of spaces between his front teeth. Diagnostic additive wax-up provided the possibility of offering minimally invasive preparations, and the use of a diagnostic intraoral mockup fulfilled the patient's esthetic demands for treatment approval. Veneer preparations over the diagnostic mockup were provided as they are minimally invasive. Ceramic veneers were hand-crafted following the previous diagnostic wax-up, and restorations were bonded under rubber dam isolation. Overall, additive wax-up provides information needed to know if minimally invasive veneer preparations are possible, and the diagnostic mockup displays a physical, tentative outcome for the patient's evaluation before irreversible tooth preparations. These simple, but effective, techniques can drive the diagnosis and prognosis of minimally invasive veneer restorations.

Soft Tissue Management on Pontic and Implant Sites Before Implants Insertion.

Complex implant therapy can include methods requiring several phases of treatment, and they are usually referred to as one-stage and two-stage approaches. The reasons for the staged approach include the extraction of non-restorable teeth. Such a treatment approach may offer a fixed provisional prosthesis during implant osseointegration that enables the patient to avoid removable prostheses. However, this case aims to demonstrate how to manage the soft tissue in the pontic region prior to immediate implant placement. A 45- years old female patient presented with non-restorable teeth from the maxillary right lateral incisor to the left lateral incisor were removed, followed by socket preservation and fixed provisional restoration from right maxillary canine to left canine. Soft tissue was contoured to achieve ovate shape by first with a tooth-supported provisional restoration from the maxillary left canine to the right canine and then by re-shaping with carbide and diamond burs; after the tissue obtained the desired architecture, implants were inserted on sites of the maxillary right lateral incisor and left central lateral incisor without immediate loading, but the same provisional fixed restoration maintained the previously contour tissue. Once implant osseointegration was achieved, screw-retained provisional restoration was placed, followed by the definitive fixed implant restoration. Because the soft tissue was previously contoured, the screw-retained implant provisional restorations maintained the tissue architecture. These initial contouring procedures provided a more predictable outcome for the final tissue contour after implants were inserted. The final re-shaping with the implant screw-retained provisional restorations was minimum, and prostheses followed the previously provided tissue architecture. Before the endosteal implants are inserted, soft-tissue contouring prior to implant placement may provide a more predictable outcome of the final tissue architecture for pontic and implant areas. The patient and clinician can evaluate the success and limitations of tissue contouring prior to implant placement. It may also shorten the time required for tissue contouring with provisional implant restorations.

Novel translucent monolithic zirconia fixed restorations in the esthetic zone.

Novel translucent monolithic zirconia has improved optical properties, and it may fulfill patient's esthetic demands and overcome the chipping risk of bilayer metal-ceramic restorations. New zirconia's microstructures allow us to mimic natural teeth.

Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) Complete Dentures for Atrophic Alveolar Ridges: Workflow Combining Conventional and Novel Techniques.

Extreme residual ridge resorption is a challenging clinical situation for the fabrication of complete dental prostheses. Computer-aided design and computer-aided manufacturing (CAD/CAM) complete dentures have been shown to have superior fit and material strength to conventionally fabricated dentures, but no clinical protocols have been described for cases of extreme residual ridge resorption. This report describes a workflow combining conventional and novel techniques for CAD/CAM complete dentures fabrication for atrophic alveolar ridges and demonstrates that a CAD/CAM workflow is an effective tool for solving this complex situation.

Circulating Tumor Cells Enumeration from the Portal Vein for Risk Stratification in Early Pancreatic Cancer Patients.

BACKGROUND: Effective biomarkers are needed to enable personalized medicine for pancreatic cancer patients. This study analyzes the prognostic value, in early pancreatic cancer, of single circulating tumor cell (CTC) and CTC clusters from the central venous catheter (CVC) and portal blood (PV). METHODS: In total, 7 mL of PV and CVC blood from 35 patients with early pancreatic cancer were analyzed. CTC were isolated using a positive immunomagnetic selection. The detection and identification of CTC were performed by immunocytochemistry (ICC) and were analyzed by Epi-fluorescence and confocal microscopy. RESULTS: CTC and the clusters were detected both in PV and CVC. In both samples, the CTC number per cluster was higher in patients with grade three or poorly differentiated tumors (G3) than in patients with well (G1) or moderately (G2) differentiated. Patients with fewer than 185 CTC in PV exhibited a longer OS than patients with more than 185 CTC (24.5 vs. 10.0 months; p = 0.018). Similarly, patients with fewer than 15 clusters in PV showed a longer OS than patients with more than 15 clusters (19 vs. 10 months; p = 0.004). These significant correlations were not observed in CVC analyses. CONCLUSIONS: CTC presence in PV could be an important prognostic factor to predict poor prognosis in early pancreatic cancer. In addition, the number of clustered-CTC correlate to a tumor negative differentiation degree and, therefore, could be used as a diagnostic biomarker for pancreatic cancer.

A customized metal guide for controllable modification of anterior teeth contour prior to minimally invasive preparation.

OBJECTIVE: Optimal tooth reduction is a key requirement for aesthetics, function, and the longevity of fixed restorations. Research has demonstrated that controlled and conservative tooth preparation is crucial for the long-term success of adhesive restorations. Different techniques of fabricating reduction guides have been previously reported in literature. The present technical note describes the fabrication technique and clinical application of a customized metal preparation reduction guide. MATERIAL AND METHOD: Patient presented with tilted maxillary left central incisor. The flared-out part of the tooth was modified prior to veneer restoration preparation. Resin pattern reduction guide was fabricated on the diagnostic cast with a window on the tilted mesial portion of the tooth. After intraoral evaluation, resin pattern guide was casted. Metal reduction guide was place intraorally and reduction was provided on the exposed surface of the tooth. After the removal of the tilted portion, a harmonious arch form allowed the clinician to provide adequate evaluation and preparation for veneer restorations. RESULTS: The device demonstrated good practical value, allowing for selective and controlled reduction of tooth structure, and definitive protection of adjacent tooth surfaces from iatrogenic damage. The clinical outcome successfully addressed the patient's restorative and aesthetic needs, and the veneer was stable 2 years postoperatively. CONCLUSION: Use of a metal guide assists clinicians to provide a more predictable reduction of a desired tooth surface, while decreasing the risk of compromising the other/adjacent tooth surfaces.

Desafios atuais na conduta clínica em pacientes com Hipertensão Arterial Sistêmica ­ HAS / Urrent challenges in the clinical management of patients with Systemic Arterial Hypertension - SAH

INTRODUÇÃO: A hipertensão arterial sistêmica (HAS) é uma doença crônica, geralmente silenciosa e de alta prevalência. O cirurgião-dentista (CD) tem papel importante no acompanhamento e detecção de HAS subdiagnosticada. Além disso, a realização de procedimentos odontológicos em pacientes hipertensos, gera diversas dúvidas quanto à conduta, principalmente relacionadas com o limiar de pressão arterial (PA) e complicações que possam surgir durante o atendimento. OBJETIVO: Descrever estratégias de conduta e intervenção durante o atendimento odontológico de pacientes com HAS. METODOLOGIA: Foi realizada uma revisão integrativa por meio da busca nas bases de dados PUBMED/MEDLINE®, SCOPUS® e Web of Science com os seguintes descritores, "Hypertension AND Dental care AND Oral health". Foram incluídos os artigos que abordassem conduta odontológica em paciente com HAS, estivessem em inglês, disponíveis on-line e sem restrição de período. RESULTADOS: Foram encontrados 570 artigos que, depois da aplicação dos critérios de inclusão e exclusão, resultaram em sete artigos para leitura de texto completo. Verificou-se que todos eles tinham origem nos Estados Unidos da América, sendo que seis estudos eram revisões. CONCLUSÃO: Os estudos mostraram que não há necessidade de suspender os procedimentos odontológicos em pacientes assintomáticos com PA abaixo de 180-110 mmHg. Entretanto, sempre é preciso avaliar o perfil de risco, a presença de sintomas cardiovasculares, a extensão do procedimento odontológico, a necessidade de protocolo de redução de ansiedade e considerar o risco e benefício da intervenção.

Rubber Dam Isolation for Bonding Ceramic Veneers: A Five-Year Post-Insertion Clinical Report.

It has been well-documented that uncontaminated ground enamel provides the most predictable substrate for the bonding of ceramic veneers, and thus conservative tooth preparation with complete isolation using a rubber dam is key to the long-term success of the restorations presented with five years of follow-up. Rubber dam isolation provides several advantages to the clinician, such as preventing contamination of the working field by saliva, blood, and sulcular fluids, and improving direct visibility. However, it may be a challenge to the younger clinician to properly isolate teeth prior to bonding ceramic veneer. The present case report demonstrated the sequence and some clinical tips for a case in which the rubber dam is placed from a second premolar to the opposite second premolar and held with clamps, the rubber dam is gently invaginated into the sulcus, and clamps are selected and placed on each tooth to create an ideal situation for the adhesion of the ceramic veneer. This step-by-step sequence may help the younger clinician in understanding how to gently manage soft tissue in order to properly provide complete isolation with rubber dam for future bonding of ceramic veneers. Following these methods, the clinician can achieve complete isolation, invaginate the rubber dam in the sulcus without causing tissues to bleed, and reduce the time needed for bonding procedures.

Conservative approach for management of fractured maxillary central incisors in young adults.

Ceramic restorations could be an acceptable treatment choice for fractured central incisors. A successful esthetic and conservative result to restore damaged anterior teeth can be obtained through proper evaluation, diagnostic wax-up, guided minimal preparations, ceramic selection, and bonding protocols. Handcrafted glass-based restorations can mimic contours and shape of natural teeth.

Combining a single implant and a veneer restoration in the esthetic zone.

OBJECTIVE: The combination of partial edentulism and a worn anterior tooth in the esthetic zone can be a challenge for the dentist. This clinical situation requires extensive knowledge of soft and hard tissue management, surgical planning and execution for implant therapy, and conservative tooth preparation with ideal bonding protocols for the tooth-supported prosthesis. Moreover, an optimal selection of the final restorative materials is imperative to manage occlusal forces and fulfill the patient's esthetic demands. MATERIALS AND METHODS: The patient presented with partial edentulism on site 11, a worn incisal edge, and facial defects on tooth 21. Minimally invasive implant therapy for site 11 was performed with a papilla-sparing flap design that only included the edentulous site, and the soft tissue contouring was started for an immediate provisional restoration. A suturing technique was executed that aimed at maintaining an interproximal papilla. Conservative veneer preparation was performed on tooth 21 in order to bond the restoration to the enamel structure. Final restorations included a custom abutment with a lithium disilicate fused to zirconia crown for the implant on site 11 and a lithium disilicate veneer on tooth 21. CONCLUSIONS: A well-planned single implant and a ceramic veneer restoration was able to fulfill the patient's esthetic expectations. The selection of materials for the final restoration was crucial to manage the occlusal forces and to mimic the shade and shape of the adjacent teeth.

Minimally invasive technique for non-vital tooth bleaching using traditional Japanese paper.

The purpose of this case report is to describe a minimally invasive technique for non-vital tooth bleaching using traditional Japanese paper, known as washi. Non-vital tooth bleaching with a mixture of sodium perborate and 30% hydrogen peroxide rolled in Japanese paper for a traumatically injured tooth, and in-office vital-tooth bleaching for the upper front six teeth and first premolars, were performed. Five-year follow-up showed satisfactory stability in the bleaching effects and did not show any problems in the traumatically injured tooth. The use of Japanese paper for non-vital tooth bleaching may minimize damage to discolored non-vital teeth.