ABSTRACT
Survival and changes in mean body mass of whole-body irradiated mice were determined to examine the radioprotectant activity of 5-diethylsulfonamoylsalicylatocopper(II) [Cu(II) (5-DESS)]. One of four groups of 25 female C57BL/6 mice were treated subcutaneously (sc)with 0, 10, 20, 40, 60, 80, 100, or 120 mumol Cu(II)(5- DESS)/kg of body mass 3 hours before exposure to 8.0 Gy, gamma irradiation. In this paradigm, doses of Cu(II)(5- DESS) increased survival up to 92% above vehicle-treated control mice (P = 0.008). Mean body mass determinations revealed that mice treated with 80 to 120 mumol Cu(II)(5-DESS)/kg of body mass exhibited a smaller decrease in body mass than other complex-treated groups. These results support the hypothesis that Cu(II)(5-DESS) is an effective radioprotectant.
Subject(s)
Eyelids/surgery , Surgery, Plastic/history , Conjunctiva , History, 20th Century , HumansABSTRACT
A simple technique for reduction of the earlobe is presented. This technique, unlike previously reported ones, leaves no scars visible on the anterior surface of the earlobe. Because of its simplicity, this technique leaves little chance for error.
Subject(s)
Ear, External/surgery , Surgery, Plastic/methods , Female , Humans , Middle AgedABSTRACT
A child with a cleft palate and mental retardation was found to have a malignant mucoepidermoid carcinoma of a minor salivary gland at the age of 18 months. The management of this case is presented.
Subject(s)
Carcinoma/surgery , Salivary Gland Neoplasms/surgery , Salivary Glands, Minor , Salivary Glands , Carcinoma/pathology , Humans , Infant , Male , Salivary Gland Neoplasms/pathology , Salivary Glands/surgery , Salivary Glands, Minor/pathology , Salivary Glands, Minor/surgeryABSTRACT
A simple method, based on scientific evidence, for the selection of a proper sun protective agent has been presented. To make it even easier, the surgeon need only look for a product containing both PABA and titanium dioxide. The author is aware there may be many other fine products available but not mentioned here, and some of those mentioned here serve the purpose for which they were designed but may not do all the things the plastic surgeon desires. In any event, the statements made herein should not be construed as an endorsement of one product over another.
