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Med Mycol ; 48(1): 177-81, 2010 Feb.
Article in English | MEDLINE | ID: mdl-19306215

ABSTRACT

We describe a case of congenital acquired candidiasis in a preterm female delivered through Caesarean section due to the premature rupture of the amniotic membrane. The neonate presented with suspected chorioamnionitis and erythematous desquamative skin. Candida albicans was isolated from the placenta, mouth, groin, and periumbilical lesions. The infant developed candidemia due to Candida albicans and the same yeast was also isolated from a catheter. Culture inoculated with swabs from the mouth and vagina of the mother yielded C. albicans and C. krusei. All C. albicans isolates from the mother and the neonate were visually indistinguishable by molecular typing techniques which included chromosomal karyotyping and restriction endonuclease analysis followed by pulsed-field gel electrophoresis. These findings allowed the clinical condition to be confirmed as congenital acquisition of candidiasis in this case.


Subject(s)
Candida albicans/isolation & purification , Candidiasis/diagnosis , Candidiasis/transmission , Infectious Disease Transmission, Vertical , Pregnancy Complications, Infectious/microbiology , Candida albicans/classification , Candida albicans/genetics , Catheterization , DNA Fingerprinting , Environmental Microbiology , Female , Fungemia/microbiology , Genotype , Groin/microbiology , Humans , Infant, Newborn , Karyotyping , Mothers , Mouth/microbiology , Mycological Typing Techniques , Placenta/microbiology , Polymorphism, Restriction Fragment Length , Pregnancy , Premature Birth , Umbilicus/microbiology
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