[Presurgical hypogastric lymph node marking under CT guidance, aided by hidrodissection] / Marcación prequirúrgica de ganglio hipogástrico con tomografía computada asistido por hidrodisección.

Introduction: Pre-surgical lymph node marking is an established medical procedure of vital importance in the treatment of cancer patients. Materials: A 60-year-old man with a history of prostatic adenocarcinoma in a plan for resection of hypogastric adenopathy. Image guided pre-surgical marking was indicated. Results: Preoperative marking was performed with local anesthesia under computed tomography with transosseous access and hydrodissection. Conclusion: We present a technique that has been little studied and rarely reported in the international literature for the surgical identification of deep pelvic adenopathy.

Introducción: La marcación pre quirúrgica de ganglios es un procedimiento médico establecido y de vital importancia en el tratamiento de pacientes oncológicos. Materiales: Hombre de 60 años con antecedentes de adenocarcinoma prostático en plan de resección de adenopatía hipogástrica. Se indicó marcación prequirúrgica mediante guía imagenológica. Resultados: Se realizó marcación prequirúrgica con anestesia local bajo tomografía computada con acceso transóseo e hidrodisección. Conclusiones: presentamos una técnica poco estudiada y escasamente reportada en la bibliografía internacional para la identificación quirúrgica de una adenopatía pélvica profunda.

[Laparoscopic adenomectomy versus open adenomectomy: A comparative study.] / Adenomectomía simple laparoscópica versus adenomectomía simple abierta: un estudio comparativo.

INTRODUCTION: The improvements in laparoscopic urological surgery have made laparoscopic adenomectomy (LA) possible in voluminous prostatic adenomas. OBJECTIVE: The objective of this study was to assess the results of the LA and compared them with results of the open adenomectomy (OA). MATERIAL AND METHODS: A comparative study of 41 patients undergoing LA [23 LA with Millin technique (LA-MT) and 21 with transvesical technique (LA-TV)] was conducted with 44 patients undergoing OL in prostate adenomas > 100 grams. Data were recorded prospectively, at three different institutions. Preoperative, intraoperative, postoperative and complications results were evaluated. RESULTS: Prostate volume was 165 (100-345) gr for LA versus 170 (100-328) gr for OA (p=0.669). Preoperative IPSS was 3 (0-3) and Q max. 7 (0-15) for LA against 2 (0-3) and 7 (0-15.3) for OA (p=0.296;p=0.316). There was no difference in surgical time (p=0.069) between both techniques. LA had less operative bleeding, 100 (10-1000) ml than OA, 500 (100-1000) ml (p=0.0001) and a shorter hospital stay, 3 (1-8) days against 3.5 (3-10) days (p=0.0001), postoperative IPSS was 1 (1-2) and Q max. 25 (17-45) for LA against 1 (1-3) and 25.5 (12-44) for OA (p=0889;p=836). There were no differences neither in transfusions requirements' nor complications. CONCLUSION: LA presented similar short-term functional results with less operative bleeding and shorter hospitalization time than OA with similar prostate volumes resected.

INTRODUCCIÓN: Los avances en la cirugía laparoscópica urológica han permitido la realización de la adenomectomía simple laparoscópica (ASL) en adenomas prostáticos voluminosos. OBJETIVO: El objetivo de este estudio fue evaluar los resultados de la ASL y compararlos con la adenomectomía simple abierta (ASA). MATERIAL Y METODOS: Se realizó un estudio comparativo de 41 pacientes sometidos a ASL [23 ASL con técnica de Millin (ASL-TM) y 21 con técnica transvesical (ASL-TV)] con 44 pacientes sometidos a ASA en adenomasde próstata > 100 gramos. Los datos se registraron de modo prospectivo, en tres centros diferentes. Se evaluaron los resultados preoperatorios, operatorios, postoperatorios y complicaciones según escala de Clavien. RESULTADOS: El volumen prostático fue 165 (100-345) gr para ASL contra 170 (100-328) gr para ASA (p=0,669). IPSS preoperatorio 3 (0-3) y Q máx. 7 (0-15) para ASL contra 2 (0-3) y 7 (0-15,3) para ASA (p=0,296; p=0,316). No hubo diferencia tiempo quirúrgico (p=0,069). ASL tuvo menos sangrado operatorio100 (10-1000) ml que la ASA 500 (100-1000) ml (p=0,0001) y una menor estadía hospitalaria 3 (1-8) días contra 3,5 (3-10) días (p=0,0001), IPSS postoperatorio1 (1-2) y Q máx. 25 (17-45) para ASL contra 1(1-3) y 25,5 (12-44) para ASA (p=0889; p=836). No hubo diferencias en el requerimiento de transfusiones ni complicaciones.CONCLUSIÓN: La ASL presentó similares resultados funcionales a corto plazo con un menor sangrado operatorio y tiempo de hospitalización que la ASA y una baja tasa de complicaciones a similares volúmenes prostáticos resecados.

Adenomectomía simple laparoscópica versus adenomectomía simple abierta: un estudio comparativo / Laparoscopic adenomectomy versus open adenomectomy: A comparative study

INTRODUCCIÓN: Los avances en la cirugía laparoscópica urológica han permitido la realización de la adenomectomía simple laparoscópica (ASL) en adenomas prostáticos voluminosos. OBJETIVO: El objetivo de este estudio fue evaluar los resultados de la ASL y compararlos con la adenomectomía simple abierta (ASA). MATERIAL Y METODOS: Se realizó un estudio comparativo de 41 pacientes sometidos a ASL [23 ASL con técnica de Millin (ASL-TM) y 21 con técnica transvesical (ASL-TV)] con 44 pacientes sometidos a ASA en adenomasde próstata > 100 gramos. Los datos se registraron de modo prospectivo, en tres centros diferentes. Se evaluaron los resultados preoperatorios, operatorios, postoperatorios y complicaciones según escala de Clavien. RESULTADOS: El volumen prostático fue 165 (100-345) gr para ASL contra 170 (100-328) gr para ASA (p = 0,669). IPSS preoperatorio 3 (0-3) y Q máx. 7 (0-15) para ASL contra 2 (0-3) y 7 (0-15,3) para ASA (p = 0,296; p = 0,316). No hubo diferencia tiempo quirúrgico (p = 0,069). ASL tuvo menos sangrado operatorio100 (10-1000) ml que la ASA 500 (100-1000) ml (p = 0,0001) y una menor estadía hospitalaria 3 (1-8) días contra 3,5 (3-10) días (p = 0,0001), IPSS postoperatorio1 (1-2) y Q máx. 25 (17-45) para ASL contra 1(1-3) y 25,5 (12-44) para ASA (p = 0889; p = 836). No hubo diferencias en el requerimiento de transfusiones ni complicaciones. CONCLUSIÓN: La ASL presentó similares resultados funcionales a corto plazo con un menor sangrado operatorio y tiempo de hospitalización que la ASA y una baja tasa de complicaciones a similares volúmenes prostáticos resecados

INTRODUCTION: The improvements in laparoscopic urological surgery have made laparoscopic adenomectomy (LA) possible in voluminous prostatic adenomas. OBJECTIVE: The objective of this study was to assess the results of the LA and compared them with results of the open adenomectomy (OA). MATERIAL AND METHODS: A comparative study of 41 patients undergoing LA [23 LA with Millin technique (LA-MT) and 21 with transvesical technique (LA-TV)] was conducted with 44 patients undergoing OL in prostate adenomas > 100 grams. Data were recorded prospectively, at three different institutions. Preoperative, intraoperative, postoperative and complications results were evaluated. RESULTS: Prostate volume was 165 (100-345) gr for LA versus 170 (100-328) gr for OA (p = 0.669). Preoperative IPSS was 3 (0-3) and Q max. 7 (0-15) for LA against 2 (0-3) and 7 (0-15.3) for OA (p = 0.296; p = 0.316). There was no difference in surgical time (p = 0.069) between both techniques. LA had less operative bleeding, 100 (10-1000) ml than OA, 500 (100-1000) ml (p = 0.0001) and a shorter hospital stay, 3 (1-8) days against 3.5 (3-10) days (p = 0.0001), postoperative IPSS was 1 (1-2) and Q max. 25 (17-45) for LA against 1 (1-3) and 25.5 (12-44) for OA (p = 0889; p = 836). There were no differences neither in transfusions requirements' nor complications. CONCLUSION: LA presented similar short-term functional results with less operative bleeding and shorter hospitalization time than OA with similar prostate volumes resected

Positive surgical margins are predictors of local recurrence in conservative kidney surgery for pT1 tumors

ABSTRACT Objectives: The clinical significance of positive surgical margin (PSM) after a Nephron Sparing Surgery (NSS) is controversial. The aim of this study is to evaluate the association between PSM and the risk of disease recurrence in patients with pT1 kidney tumors who underwent NSS. Materials and Methods: Retrospective cohort study. A total of 314 patients submitted to a NSS due to stage pT1 renal tumor between January 2010 and June 2015 were included. Recurrence-free survival was estimated. The Cox model was used to adjust the tumor size, histological grade, pathological stage, age, surgical margins and type of approach. Results: Overall PSM was 6.3% (n=22). Recurrence was evidenced in 9.1% (n=2) of patients with PSM and 3.5% (n=10) for the group of negative surgical margin (NSM). The estimated local recurrence-free survival rate at 3 years was 96.4% (95% CI 91.9 to 100) for the NSM group and 87.8% (95% CI 71.9 to 100) for PSM group (p=0.02) with no difference in metastasis-free survival. The PSM and pathological high grade (Fuhrman grade III or IV) were independent predictors of local recurrence in the multivariate analysis (HR 12.9, 95%CI 1.8-94, p=0.011 / HR 38.3, 95%CI 3.1-467, p=0.004 respectively). Fuhrman grade proved to be predictor of distant recurrence (HR 8.1, 95%CI 1.6-39.7, p=0.011). Conclusions: The PSM in pT1 renal tumors showed to have higher risk of local recurrence and thus, worse oncological prognosis.

Positive surgical margins are predictors of local recurrence in conservative kidney surgery for pT1 tumors.

OBJECTIVES: The clinical significance of positive surgical margin (PSM) after a Nephron Sparing Surgery (NSS) is controversial. The aim of this study is to evaluate the association between PSM and the risk of disease recurrence in patients with pT1 kidney tumors who underwent NSS. MATERIALS AND METHODS: Retrospective cohort study. A total of 314 patients submitted to a NSS due to stage pT1 renal tumor between January 2010 and June 2015 were included. Recurrence-free survival was estimated. The Cox model was used to adjust the tumor size, histological grade, pathological stage, age, surgical margins and type of approach. RESULTS: Overall PSM was 6.3% (n=22). Recurrence was evidenced in 9.1% (n=2) of patients with PSM and 3.5% (n=10) for the group of negative surgical margin (NSM). The estimated local recurrence-free survival rate at 3 years was 96.4% (95% CI 91.9 to 100) for the NSM group and 87.8% (95% CI 71.9 to 100) for PSM group (p=0.02) with no difference in metastasis-free survival. The PSM and pathological high grade (Fuhrman grade III or IV) were independent predictors of local recurrence in the multivariate analysis (HR 12.9, 95%CI 1.8-94, p=0.011 / HR 38.3, 95%CI 3.1-467, p=0.004 respectively). Fuhrman grade proved to be predictor of distant recurrence (HR 8.1, 95%CI 1.6-39.7, p=0.011). CONCLUSIONS: The PSM in pT1 renal tumors showed to have higher risk of local recurrence and thus, worse oncological prognosis.

[Current patterns of presentation of renal tumors]. / Formas actuales de presentación del tumor renal.

The aim of this paper is to describe the epidemiological characteristics, clinical management and pathologic patterns in a population with renal tumors in our institution. Prospective data collection was performed over a period of 4.5 years, from January 2010 to June 2014. A total of 819 cases (796 patients) were treated for renal mass during this period. The mean age was 60.7 years (SD 13.1). There were 553 (69.5%) males (male to female ratio: 2.2: 1). Twenty nine per cent (230 patients) were obese (BMI = 30). The diagnosis was incidental in 653 cases (79.7%), 48.8% presented one or more risk factors, being smoking the most frequent (34%). In 238 patients (29.9%) there was more than one comorbidity; 18% had preoperative creatinine = 1.3 mg/dl. Lesions were = 4 cm (cT1a) in 45% of the patients, and 10.8% (86) had metastases at diagnosis. The lesions were resected in 93.5% and actively monitored in 6.5% (not resected). In surgery treated patients, radical nephrectomy was performed in 51.5% of cases, and nephron sparing surgery in 48.5% of them. The laparoscopic approach was used in 56.2%. The pattern of presentation of renal masses is characterized by incidental diagnosis in early disease stages. Nephron sparing surgery is the first choice in nearly half of patients. Active surveillance has been used in a greater percentage than previously reported.

Formas actuales de presentación del tumor renal

El objetivo del trabajo es describir las características epidemiológicas de la población con tumores renales en nuestra institución, la estrategia de diagnóstico y tratamiento y los hallazgos anatomo-patológicos. Se realizó una recolección prospectiva de datos epidemiológicos, de diagnóstico y tratamiento, así como también de los resultados patológicos en un período de 4.5 años, desde enero de 2010 a junio de 2014. En ese lapso 819 casos (796 pacientes) fueron tratados por masa renal. La edad media: 60.7 años (DE 13.1), 553 (69.5%) fueron hombres. El 29% (230) presentó obesidad (IMC ≥ 30). El diagnóstico fue incidental en 653 casos (79.7%). Un 48.8% (388 pacientes) presentó uno o más factores de riesgo, siendo el tabaquismo el más frecuente (34%). En 238 pacientes (29.9%) se presentó más de una comorbilidad. El 18% presentó creatinina preoperatoria ≥ a 1.3 mg/dl. El 45% de las lesiones fueron ≤ a 4 cm (cT1a). El 10.8% (86) de los pacientes presentaron metástasis al diagnóstico. El 93.5% de las lesiones fueron resecadas y el 6.5% fueron vigiladas activamente (no resecadas). Se utilizó la nefrectomía radical en el 51.5% y cirugía renal conservadora en el 48.5% de los pacientes operados. El abordaje laparoscópico fue utilizado en el 56.2%. El tumor renal se caracteriza en la actualidad por un diagnóstico incidental en estadios patológicos iniciales. La cirugía renal conservadora es la primera opción en casi la mitad de los pacientes. La vigilancia activa ha sido utilizada en un porcentaje mayor a lo comunicado en la literatura.

The aim of this paper is to describe the epidemiological characteristics, clinical management and pathologic patterns in a population with renal tumors in our institution. Prospective data collection was performed over a period of 4.5 years, from January 2010 to June 2014. A total of 819 cases (796 patients) were treated for renal mass during this period. The mean age was 60.7 years (SD 13.1). There were 553 (69.5%) males (male to female ratio: 2.2: 1). Twenty nine per cent (230 patients) were obese (BMI ≥ 30). The diagnosis was incidental in 653 cases (79.7%), 48.8% presented one or more risk factors, being smoking the most frequent (34%). In 238 patients (29.9%) there was more than one comorbidity; 18% had preoperative creatinine ≥ 1.3 mg/dl. Lesions were ≤ 4 cm (cT1a) in 45% of the patients, and 10.8% (86) had metastases at diagnosis. The lesions were resected in 93.5% and actively monitored in 6.5% (not resected). In surgery treated patients, radical nephrectomy was performed in 51.5% of cases, and nephron sparing surgery in 48.5% of them. The laparoscopic approach was used in 56.2%. The pattern of presentation of renal masses is characterized by incidental diagnosis in early disease stages. Nephron sparing surgery is the first choice in nearly half of patients. Active surveillance has been used in a greater percentage than previously reported.

Formas actuales de presentación del tumor renal

El objetivo del trabajo es describir las características epidemiológicas de la población con tumores renales en nuestra institución, la estrategia de diagnóstico y tratamiento y los hallazgos anatomo-patológicos. Se realizó una recolección prospectiva de datos epidemiológicos, de diagnóstico y tratamiento, así como también de los resultados patológicos en un período de 4.5 años, desde enero de 2010 a junio de 2014. En ese lapso 819 casos (796 pacientes) fueron tratados por masa renal. La edad media: 60.7 años (DE 13.1), 553 (69.5%) fueron hombres. El 29% (230) presentó obesidad (IMC ≥ 30). El diagnóstico fue incidental en 653 casos (79.7%). Un 48.8% (388 pacientes) presentó uno o más factores de riesgo, siendo el tabaquismo el más frecuente (34%). En 238 pacientes (29.9%) se presentó más de una comorbilidad. El 18% presentó creatinina preoperatoria ≥ a 1.3 mg/dl. El 45% de las lesiones fueron ≤ a 4 cm (cT1a). El 10.8% (86) de los pacientes presentaron metástasis al diagnóstico. El 93.5% de las lesiones fueron resecadas y el 6.5% fueron vigiladas activamente (no resecadas). Se utilizó la nefrectomía radical en el 51.5% y cirugía renal conservadora en el 48.5% de los pacientes operados. El abordaje laparoscópico fue utilizado en el 56.2%. El tumor renal se caracteriza en la actualidad por un diagnóstico incidental en estadios patológicos iniciales. La cirugía renal conservadora es la primera opción en casi la mitad de los pacientes. La vigilancia activa ha sido utilizada en un porcentaje mayor a lo comunicado en la literatura.(AU)

The aim of this paper is to describe the epidemiological characteristics, clinical management and pathologic patterns in a population with renal tumors in our institution. Prospective data collection was performed over a period of 4.5 years, from January 2010 to June 2014. A total of 819 cases (796 patients) were treated for renal mass during this period. The mean age was 60.7 years (SD 13.1). There were 553 (69.5%) males (male to female ratio: 2.2: 1). Twenty nine per cent (230 patients) were obese (BMI ≥ 30). The diagnosis was incidental in 653 cases (79.7%), 48.8% presented one or more risk factors, being smoking the most frequent (34%). In 238 patients (29.9%) there was more than one comorbidity; 18% had preoperative creatinine ≥ 1.3 mg/dl. Lesions were ≤ 4 cm (cT1a) in 45% of the patients, and 10.8% (86) had metastases at diagnosis. The lesions were resected in 93.5% and actively monitored in 6.5% (not resected). In surgery treated patients, radical nephrectomy was performed in 51.5% of cases, and nephron sparing surgery in 48.5% of them. The laparoscopic approach was used in 56.2%. The pattern of presentation of renal masses is characterized by incidental diagnosis in early disease stages. Nephron sparing surgery is the first choice in nearly half of patients. Active surveillance has been used in a greater percentage than previously reported.(AU)