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1.
Int J Pediatr ; 20102010.
Article in English | MEDLINE | ID: mdl-20936144

ABSTRACT

We aimed to develop a new scale for evaluating risks and preventive measures for in-hospital falls of newborn infants, from admission to discharge of the expectant mother. Our study was prepared in accordance with Failure Modes and Effects Analysis criteria. The risks and preventive measures for in-hospital falls of newborns were determined. Risk Priority Numbers (RPNs) were determined by multiplication of the scores of severity, probability of occurrence, and probability of detection. Analyses showed that risks having the highest RPNs were the mother with epidural anesthesia (RPN: 350 point), holding of the baby at the moment of delivery (RPN: 240), and transportation of baby right after delivery (RPN: 240). A reduction was detected in all RPNs after the application of preventive measures. Our risk model can function as a guide for obstetric clinics that need to form strategies to prevent newborn falls.

2.
Ann Emerg Med ; 48(4): 448-51, 2006 Oct.
Article in English | MEDLINE | ID: mdl-16997682

ABSTRACT

Methadone overdoses are increasing in parallel with the increased frequency of opiate substitution therapy in adults. Although unintentional methadone intoxication in children is rare, it is becoming more frequently recognized. We report 3 cases of unintentional methadone overdose in toddlers who initially displayed central nervous system depression associated with severe nonketotic hyperglycemia and discuss the possible pathophysiologic mechanisms of an underrecognized symptom of opiate intoxication in young children.


Subject(s)
Accidents, Home , Diagnostic Errors , Hyperglycemic Hyperosmolar Nonketotic Coma/chemically induced , Methadone/poisoning , Animals , Brain Damage, Chronic/etiology , Child, Preschool , Diabetes Mellitus, Type 1/diagnosis , Dobutamine/therapeutic use , Drug Packaging , Epinephrine/therapeutic use , Female , France , Humans , Hyperglycemic Hyperosmolar Nonketotic Coma/complications , Hyperglycemic Hyperosmolar Nonketotic Coma/diagnosis , Hyperglycemic Hyperosmolar Nonketotic Coma/drug therapy , Infant , Insulin/therapeutic use , Islets of Langerhans/drug effects , Islets of Langerhans/physiopathology , Male , Methadone/pharmacology , Mice , Multiple Organ Failure/etiology , Myocardial Infarction/etiology , Naloxone/therapeutic use , Receptor, Insulin/drug effects , Receptors, Opioid, mu/drug effects , Receptors, Opioid, mu/physiology , Shock, Cardiogenic/etiology , Sweetening Agents , Time Factors
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