ABSTRACT
Renal function (glomerular filtration) and vascular permeability were studied in 89 patients with diabetes mellitus by means of labeled renotropic compounds. There was a direct relationship between the reduced glomerular filtration, severity and duration of the disease, condition of compensation, age and body weight of diabetic patients, and the presence of diabetic vascular lesions. Vascular permeability proved to be increased in the form of diabetes mellitus and in patients with marked renal pathology.
Subject(s)
Capillary Permeability , Diabetes Mellitus/physiopathology , Kidney Glomerulus/physiopathology , Adolescent , Adult , Aged , Glomerular Filtration Rate , Humans , Kidney Glomerulus/blood supply , Middle Aged , Radioisotope Dilution Technique , Radioisotope RenographyABSTRACT
Renal function (glomerular filtration) and vascular permeability under the effect of an angioprotector were studied by means of labeled renotropic compounds in 55 patients with diabetic angiopathies. The patients were divided into 3 groups: the first group comprised 23 patients treated with anginin or prodectin alone; the second one--16 patients given dicinon or docsium, and the third one--16 patient who were given combined treatment. The best effect was noted in the latter group of patients.