ABSTRACT
Previous reports indicate that In-111 platelet scintigraphy (IPS) is a reliable test for the early diagnosis of acute post-operative renal transplant rejection (TR). However, the recent introduction of cyclosporin for post-transplantation immunosuppression requires that the diagnostic efficacy of IPS once again be established. Therefore, a prospective IPS study of 73 post-operative renal transplant recipients was conducted. Fourty-nine patients received cyclosporin and 24 patients did not receive this drug. Between these two patient groups, there were no significant differences in the diagnostic sensitivities (0.86 vs 0.80) and specificities (0.93 vs 0.84) with which TR was identified. We conclude that during the first two weeks following renal transplantation the cyclosporin treatment regimen used at our institution does not limit the reliability of IPS as a test for TR.
Subject(s)
Cyclosporins/therapeutic use , Graft Rejection/drug effects , Kidney Transplantation , Adult , Blood Platelets , Female , Humans , Indium Radioisotopes , Kidney/diagnostic imaging , Male , Middle Aged , Radionuclide ImagingABSTRACT
Bipartite liver is a rare anomaly that has no apparent phylogenetic significance but does represent a distinct category of congenital liver malformations. Although no associated complications have been known to occur, the potential for internal herniation of the gastrointestinal tract may exist.
Subject(s)
Liver/abnormalities , Adult , Humans , Imino Acids , Liver/diagnostic imaging , Male , Organometallic Compounds , Radionuclide Imaging , Technetium Tc 99m Disofenin , Tomography, X-Ray ComputedABSTRACT
A prospective evaluation of 111In-labeled platelet scintigraphy (IPS) for the early diagnosis of acute postoperative renal transplant rejection (TR) was undertaken. The results of IPS were compared with in vitro biochemical tests, the clinical finding of graft tenderness, and combined [99mTc]DTPA and [131I]orthoiodohippurate scintigraphy. With a sensitivity of 0.93 and a specificity of 0.95, IPS provided otherwise unavailable diagnostic information. Furthermore, postoperative IPS was a good predictor of long-term allograft survival.
Subject(s)
Graft Rejection , Indium , Kidney Transplantation , Radioisotopes , Acute Disease , Adolescent , Adult , Blood Platelets , Female , Humans , Kidney/diagnostic imaging , Male , Middle Aged , Postoperative Period , Prospective Studies , Radionuclide ImagingABSTRACT
While bone metastases producing photon deficient defects on bone scintigraphy have previously been reported, this finding has not been emphasized for hepatocellular carcinoma (HCC). Furthermore, "filling-in" of such photon deficient defects with 67Ga at skeletal sites of metastatic HCC has not been described. In this case report, the combination of a photon deficient defect on bone scintigraphy and avid accumulation of 67Ga in this same area was of value in confirming the diagnosis of metastatic HCC.
Subject(s)
Bone Neoplasms/secondary , Carcinoma, Hepatocellular/secondary , Gallium Radioisotopes , Liver Neoplasms/pathology , Adult , Bone Neoplasms/diagnostic imaging , Carcinoma, Hepatocellular/diagnostic imaging , Humans , Male , Radionuclide ImagingABSTRACT
We report a case of myoglobinuria secondary to prolonged seizures. The child showed "hot kidneys" with bone scintigraphy. The disease entity and etiologies of nontraumatic rhabdomyolysis are discussed.
Subject(s)
Acute Kidney Injury/diagnostic imaging , Diphosphonates , Kidney/diagnostic imaging , Rhabdomyolysis/diagnostic imaging , Technetium , Acute Kidney Injury/etiology , Adolescent , Bone and Bones/diagnostic imaging , Female , Humans , Radionuclide Imaging , Rhabdomyolysis/etiology , Seizures/complications , Technetium Tc 99m MedronateSubject(s)
Arteriovenous Fistula/diagnostic imaging , Pulmonary Artery/diagnostic imaging , Serum Albumin , Technetium , Tricuspid Valve/abnormalities , Vena Cava, Superior/diagnostic imaging , Child , Female , Humans , Lung/diagnostic imaging , Postoperative Complications , Radionuclide Imaging , Technetium Tc 99m Aggregated Albumin , Tricuspid Valve/surgeryABSTRACT
Even though Ga-67 imaging has been used widely in the diagnosis of malignant as well as inflammatory lesions, its uptake in the stomach has been reported in the literature mainly in gastric lymphoma and carcinoma. As shown in this case, intense gastric uptake of the radionuclide may be seen in common gastritis without malignancy. Perhaps the benign gastric uptake of Ga-67 deserves more emphasis.
