Subject(s)
Cardiac Output, Low/genetics , Cardiac Output, Low/therapy , Climate , Health Resorts , Polymorphism, Genetic , Calcium-Binding Proteins/genetics , Calcium-Transporting ATPases/genetics , Chronic Disease , Humans , Insulin-Like Growth Factor I/genetics , Sarcoplasmic Reticulum Calcium-Transporting ATPases , Treatment OutcomeSubject(s)
Balneology/methods , Cardiac Output, Low/therapy , Climate , Aged , Baths , Cardiac Output, Low/physiopathology , Chronic Disease , Female , Health Resorts , Hemodynamics , Humans , Male , Middle AgedABSTRACT
The aim of our study was to estimate clinical effects of spa therapy (ST) at Sochi-Macesta resort in patients with heart failure (HF). Spa therapy was given to 116 patients with HF functional class (FC) 0-II by NYHA classification. It is shown that ST leads to improvement of the patients' clinical status, reduction of HF FC (from 1.32 +/- 0.09 to 0.66 +/- 0.01, p < 0.001), to increased exercise tolerance (p < 0.05) and better 6-minute walk test results (from 460.3 +/- 11.4 m to 511.2 +/- 11.8 m, p < 0.01), higher myocardial coronary reserve, favourable shifts in blood pressure. ST also has a cardiotonic effect and corrects vegetative status, there was also antiatherogenic effect and an increase in blood coagulation potential. The received data allow us to conclude that ST can be an effective tool of medical rehabilitation in patients with initial stages of heart failure.