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Lik Sprava ; (5-6): 70-2, 1993.
Article in Russian | MEDLINE | ID: mdl-8209504

ABSTRACT

65 patients with acute hepatitis and 116 patients with chronic hepatitis of toxico-allergic nature were examined. 20 patients with acute hepatitis and 40 patients with chronic form of the disease were prescribed in addition to conventional treatment 2-4 ml i.m. of splenin daily, 20 mg of vilosen daily in 3-4 divided doses in the form of 1% solution intranasally and the same quantity--sublingually. The drugs were administered for 10-15 days. Co-administration of splenin and vilosen was established to hasten normalization of clinical indices and immune homeostasis restitution thus advocating the use of the drugs as a part of therapeutic complex in the treatment of acute and chronic toxico-allergic hepatitis.


Subject(s)
Adjuvants, Immunologic/therapeutic use , Autoimmune Diseases/drug therapy , Chemical and Drug Induced Liver Injury/drug therapy , Hepatitis/drug therapy , Thymopoietins/therapeutic use , Thymus Extracts/therapeutic use , Acute Disease , Animals , Autoimmune Diseases/immunology , Carbon Tetrachloride Poisoning/drug therapy , Carbon Tetrachloride Poisoning/immunology , Chemical and Drug Induced Liver Injury/immunology , Chronic Disease , Combined Modality Therapy , Drug Evaluation , Drug Evaluation, Preclinical , Drug Therapy, Combination , Hepatitis/immunology , Humans , Immunity, Cellular/drug effects , Rats
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