ABSTRACT
Data supplied by the active influenza surveillance - including clinical, epidemiological and laboratory investigations - allowed the characterization of the particularities of an influenza outbreak caused by A(H3N2) virus in a large town of Romania in March 1983. The epidemiological impact of influenza in 1983 is discussed in the light of the complex relationships between the antigenic structure of circulating influenza strains and the profile of antiinfluenza immunity of the population.
Subject(s)
Influenza, Human/epidemiology , Urban Population , Adolescent , Antibodies, Viral/analysis , Child , Child, Preschool , Disease Outbreaks/epidemiology , Humans , Infant , Influenza A virus/immunology , Influenza B virus/immunology , Influenza, Human/immunology , Paramyxoviridae Infections/epidemiology , Paramyxoviridae Infections/immunology , Respirovirus/immunology , Romania , SeasonsABSTRACT
The particularities of influenza evolution in a large town of Romania during 1982 are outlined on the ground of the data obtained by a complex methodology of active influenza surveillance. The epidemiological features of influenza are discussed within the complex framework of the relationships between the antigenic structure of circulating influenza viruses and the profile of antiinfluenza immunity among the population.
Subject(s)
Influenza, Human/epidemiology , Adolescent , Adult , Age Factors , Aged , Antibodies, Viral/analysis , Child , Child, Preschool , Disease Outbreaks/epidemiology , Humans , Infant , Infant, Newborn , Influenza, Human/immunology , Middle Aged , Orthomyxoviridae/immunology , Romania , SeasonsSubject(s)
Disease Outbreaks/prevention & control , Immunization , Influenza Vaccines/administration & dosage , Influenza, Human/prevention & control , Vaccines, Attenuated/administration & dosage , Antibodies, Viral/analysis , Antigens, Viral/analysis , Child , Child, Preschool , Disease Outbreaks/epidemiology , Fever/etiology , Humans , Infant , Influenza A virus/immunology , Influenza Vaccines/adverse effects , Influenza, Human/epidemiology , Romania , Time Factors , Vaccines, Attenuated/adverse effectsSubject(s)
Influenza, Human/epidemiology , Adolescent , Adult , Age Factors , Aged , Antibodies, Viral/analysis , Child , Child, Preschool , Hemagglutination Inhibition Tests , Humans , Infant , Infant, Newborn , Influenza, Human/diagnosis , Middle Aged , Orthomyxoviridae/isolation & purification , Romania , Seasons , Urban PopulationSubject(s)
Disease Outbreaks/epidemiology , Influenza, Human/epidemiology , Adolescent , Adult , Age Factors , Aged , Antibodies, Viral/analysis , Child , Child, Preschool , Disease Reservoirs , Humans , Infant , Influenza A virus/isolation & purification , Influenza, Human/diagnosis , Middle Aged , Romania , Seasons , Urban PopulationABSTRACT
Seroepidemiological investigations performed with 1,620 serum samples and serodiagnostic tests with 166 paired sera demonstrated that swine influenza virus type A/New Jersey 8/76 (Hsw1N1) played no role in the epidemiology of human influenza in a large town of Romania during 1977.
Subject(s)
Hemagglutinins, Viral/analysis , Influenza A virus/immunology , Influenza, Human/immunology , Adolescent , Adult , Child , Humans , Influenza, Human/etiology , Middle Aged , RomaniaSubject(s)
Disease Outbreaks/epidemiology , Influenza, Human/epidemiology , Adolescent , Adult , Age Factors , Antibodies, Viral/analysis , Child , Child, Preschool , Humans , Infant , Influenza A virus/isolation & purification , Influenza, Human/complications , Influenza, Human/immunology , Romania , Rural Population , Seasons , VaccinationABSTRACT
Results are presented of the complex epidemiological influenza surveillance in a large town of Romania during 1975. The comprehensive and unitary methodology including systematic laboratory, clinical and epidemiological investigations supplied data on the influenza type A outbreak recorded during the first term of 1975. The factors of importance for epidemiological prognosis -- seroepidemiological indicators of the immunological profile of the population according to age groups, serodiagnostic and virological investigation clinically diagnosed influenza cases, complex epidemiological surveys in representative foci, study of the antigenic structure of the influenza strains isolated -- are outlined. The importance of a continuous, complex influenza surveillance for the differential orientation of prophylaxis and control steps is emphasized.
Subject(s)
Influenza, Human/epidemiology , Adolescent , Adult , Age Factors , Aged , Antibodies, Viral/analysis , Child , Child, Preschool , Disease Outbreaks , Humans , Infant , Influenza A virus/isolation & purification , Middle Aged , Romania , SeasonsABSTRACT
The present paper reports on the results of a complex epidemiologic survey of the epidemiologic potential of influenza in Bucharest in 1974, conducted on the basis of a complete, unitary methodology including; (a) Dynamic survey of the morbidity and mortality from influenza, with statistical-mathematical processing of the data per age group and total population; (b) Monthly sero-epidemiologic survey of the antiinfluenza immunologic profile of the population, determined in lots of 540 sera (annual total 7020 serum samples), with statistical-mathematical processing of the serograms; (c) Serodynamic determinations of 67 paired serum smaples collected from patients presenting influenza syndromes during ascension of the epidemic morbidity from influenza; (d) Complex epidemiologic surveys in representative influenza foci in children, adolescent and adult communities. Based upon the result obtained the authors discuss the evolutive particularities of the epidemiologic process in Bucharest, particularly during the epidemic ascension of the first trimester of 1974, caused by the intensified circulation of influenza virus type B. The orientative value of certain elements for the epidemiologic prognosis is emphasized, such as: the immunologic profile of the population per age group with regard to the circulating influenza virus strains (autochtonous or imported strains), active control of the incidence of influenza in communities (technical schools etc.) or enterprises with a large number of employees, laboratory etiologic determinations in cases of a clinical diagnosis of influenza in a preepidemic season. The authors' ten years experience in the active survey of the active epidemiologic potential of influenza in the town of Bucharest shows that the methodology applied was efficient both for scientific assessing of the epidemiologic situation and for an orientation in the choice of preventive and control measures.
Subject(s)
Influenza, Human/epidemiology , Adolescent , Adult , Age Factors , Child , Child, Preschool , Epidemiologic Methods , Humans , Infant , Romania , Urban PopulationABSTRACT
Active survey of the epidemiologic potential of cerebrospinal meningitis, in Bucharest, starting in 1967, made it possible to carry out a complex study of the last epidemic wave in 1968-1972. Details are given concerning the results of the complex epidemiologic, clinical and laboratory investigations, which revealed the particularities of this epidemic episode, including the frequency and gravity of the cases, territorial distribution, prevalent affection of certain age groups and children's communities, the prevalence of certain clinical forms, antigenic structure of the pathogenic agent and its sensitivity to antibiotics, comparative efficiency of the different methods of laboratory diagnosis, real and apparent contagiousness, etc. The authors discuss the efficiency of present methods applied in the prevention and control of meningococcal infections in general and of epidemic cerebrospinal meningitis in particular.
Subject(s)
Meningitis, Meningococcal/epidemiology , Adolescent , Adult , Age Factors , Child , Child, Preschool , Humans , Infant , Meningitis, Meningococcal/complications , Meningitis, Meningococcal/mortality , Romania , Seasons , Urban PopulationABSTRACT
Analysis of the evolution of the main epidemiologic indices showed that epidemic cerebrospinal meningitis evolved during the last two decades in our country according to the general evolution of this disease in most of the developed countries in the temperate zone, however with certain particular elements revealed by the data obtained in the country and in Bucharest. Details are given for the town in Bucharest, during the 1951-1973 period, concerning the general trends of the frequency and gravity indices of the cases, the structure per age groups of the morbidity, the forms of manifestation of the epidemiologic process. Stress is laid on the seasonal character (winter-spring) of the increase in the number of cases and the periodicity of the epidemic waves.
