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1.
Hum Hered ; 45(6): 351-4, 1995.
Article in English | MEDLINE | ID: mdl-8537083

ABSTRACT

Alpha-1-antitrypsin phenotypes of umbilical cord serum from 741 Polish newborns were studied by isoelectric focusing. The frequencies of the PI alleles were: PI*M1 = 0.7199, PI*M2 = 0.1613, PI*M3 = 0.0965, PI*S = 0.0094, PI*Z = 0.0067, and PI*Var(F,I,L) = 0.0060. The data obtained for Poland were compared to those for other European populations.


Subject(s)
Infant, Newborn/metabolism , alpha 1-Antitrypsin/genetics , Fetal Blood/chemistry , Humans , Isoelectric Focusing , Phenotype , Poland
2.
Hum Hered ; 42(6): 384-6, 1992.
Article in English | MEDLINE | ID: mdl-1493917

ABSTRACT

alpha-1-antitrypsin (PI) subtypes were studied in Poles and Russians. The frequencies of the PI alleles were similar in the two populations, with the exception of the Z allele, whose frequency was significantly lower in Poles. The M3 allele frequency, which is highly heterogeneous in European populations, has medium frequencies in Poles and Russians.


Subject(s)
Alleles , alpha 1-Antitrypsin/genetics , Adult , Gene Frequency , Humans , Poland , Polymorphism, Genetic , Russia
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