[A research into the possibility of the application of new peroxosolvate-based compounds as chemical disinfectants].

A newly synthesized peroxosolvate, ammonium sulphate peroxosolvate, can be used in disinfectology and other areas along with other hard forms of hydrogen. Optimal conditions for ammonium sulphate peroxosolvate synthesis were determined by this study. It was established that (NH4)2SO4 . H2O2 stabilized with carboxylic acids did not lose active oxygen when stored in dry atmosphere. The sporocidal activity of the compound against the suspension of B. cereus var. anthracoides 250 was studied. The results demonstrate that thanks to the high decontaminating activity of the solvate its solutions can be used to produce disinfecting preparations.

[Chemicals for disinfection and decontamination used and being designed for eliminating the aftermaths of biological contamination]. / Khimicheskie sredstva dezinfektsii i dekontaminatsii, primeniaemye i razrabatyvaemye dlia likvidatsii posledstvii biologicheskogo zarazheniia.

The efficiency of the key classes of disinfecting and decontaminating chemicals, used to eliminate a biological contamination of the human habitat, was analyzed in the paper. It is underlined that, should any biological agents with unknown properties (biological terror, military threat) be detected, it is advisable to choose the ecologically less hazardous disinfectants based on hydrogen peroxide, aldehydes and chlorine-containing compounds.

[The sporicidal activity of disinfectants based on hydrogen peroxide]. / Sporotsidnaia aktivnost' dezinfitsiruiushchikh sredstv na osnove peroksida vodoroda.

The authors analyzed the experience of disinfection experts related with the designing of new disinfection chemicals and of their composition variations. The key regularities were defined, which are important for the designing of effective disinfectants with preset properties capable of rapidly and safely inactivating a microbe contamination of different objects in the human habitat. A high antimicrobial activity and good outlooks are demonstrated for disinfectants made on the basis of hydrogen peroxide.

[Problems of disinfection and decontamination in the biological protection and prevention of contagious diseases]. / Problemy dezinfektsii i dekontaminatsii v sisteme biologicheskoi zashchity i profilaktiki infektsionnykh zabolevanii.

The problems of biological protection of the general population and military staff against biological hazard sources, primarily against biological terrorism and military threat underlie works on the design of new disinfectants having a universal spectrum of antimicrobial action and less ecological hazard than currently available ones. Elimination of biological hazard require effective chemical disinfectants that can completely inactivate microbes of unknown etiology as rapidly as possible and that cause the minimum damage to environmental objects. The disinfectant PFK of various modifications is evaluated in terms of the requirements of that ecological and chemical concept aimed at testing chemicals entering the environment.

[The development of a technology for producing a new disinfecting agent with a universal spectrum of antimicrobial action]. / Razrabotka tekhnologii polucheniia novogo dezinfektsionnogo sredstva s univeral'nym spektrom antimikrobnogo deistviia.

The paper summarizes the findings of the physicochemical and potency of potassium fluoride peroxohydrate (PFP-1), a new Russian disinfecting agent having a universal spectrum of antimicrobial effects. It also summarizes the results of long-term practical use for the routine and final disinfection of rooms, sanitary engineering equipment, glassware, medical instruments against both sanitary indicative microorganisms, and actual pathogens of disease in infective and somatic hospitals, tuberculous dispensaries, sanatoria, schools, kindergartens, military hospitals, maternity houses of Russian different cities, towns, and localities. The paper presents comparative data on the mechanism of action of various modifications of PFP on microbial spores, on the stability of agents and their solutions during storage, on the damaging activity on the materials of the processed objects, on toxicological and ecological risks. The results of comparative studies of the bactericidal and sporicidal activities of the modifications PFP-1, PFP-2, PFP-3 confirmed that it is necessary to develop a procedure for preparing modifications containing high levels of hydrogen peroxide in the dry preparation and that they can be obtained at the pilot unit developed to prepare PFP-1 modifications.